DNP has been around since the turn of the century. Although not used as a diet aid or weight loss supplement to begin with, it was eventually found to be a very effective weight loss drug. It is an industrial chemical first being used to ignite TNT in the 1900's. It has also been used as a bug pesticide (melting the bug from the inside out), fabric dye and then a Stanford University study showed that it caused significant weight loss and has been used for that purpose since the 1930's. Hitler used it in the concentration camps during World War 2 to keep prisoners warm during the winter without the need for heating the buildings.
DNP is a mitochondrial uncoupler of oxidative phosphorylation, boosting the metabolism up to 50% by inhibition of the FOF1 ATP synthesis molecule located in the inner wall of mitochondria. As a result, ATP production is dramatically reduced and the energy is turned into heat. A 30- 50% increase in metabolic rate makes this the 'mother' of all fat burners. Compared to other thermogenic compounds such as ephedrine/aspirin/caffeine (ECA) which has a boost of about 3% and clenbuterol /cytomel which has a boost of about 10%.
Unlike clen/t3 and ECA, DNP won't boost body temperature to the same degree. DNP will only cause an increase of 1-1.5 degree Celsius. DNP competes with the thyroid for carrier proteins. Even though Thyroid Stimulating Hormone (STH) and free thyroid levels maybe normal, they are being excreted instead of being used. To extend the length of a DNP cycle, T3 could be added, but most people don't absorb T3 very well, which causes levels of T3 to become way too high. Therefore, it is ill advised and not recommended. It is better to use it on a rotating 8-day cycle with a 7 day off period. During this 2 week period you will look best on the 14th day after the water being retained is dropped. T3 in the amount of 25-50 mcg per day during the off week will also help restore normal thyroid levels.
The main problem with DNP use is the severity of side effects. Since there are no negative feedback loops to deal with possible overdose, there is no limit to how hot you can make your body. Death is a definite possibility if too much is used. The "more is better"rule does not pertain to this drug. Side effects include insomnia, yellow body fluids (urine, sweat, sperm etc.), muscle soreness (reps during workouts will need to be kept light with at least 15 reps), overheating, carcinogenesis, (although DNP has never been associated with cancer) discomfort, lethargy, sweating, carb cravings, stroke, kidney damage, brain damage, and DEATH. These are all very possible as the lethal dose is only four times that of the normal dose.
This drug is not anorectic so you will be hungry on DNP. Ten percent of some users experience allergic reactions (hives, blisters, rashes etc.) and a .1% of users get cataracts. DNP users will also feel lethargic due to the glucose being transferred into the cells without the use of insulin.
Dosages were put after the side effects because this is a chemical that is not forgiving and it is more important that everyone understands what the side effects are before trying to acquire DNP and use it. Doses range between 2-8mgs/kg of body weight, NOT lean body mass. It's best dosed at 200mgs/d for someone in an active type job (landscaper, construction worker etc.), 400-600mgs/d for most others and only 800mgs/d for the morbidly obese. Although doses at 1gm/d have been used they are not recommend. DNP has an accumulative affect due to its 36-hour half-life. When users don?t feel their body temperature rise, DO NOT INCREASE DOSAGE. 30mg/kg are the lethal dose and are very possible if the dose is above 800mgs/d.
Here are some ideas to try to help users deal with their DNP use. DNP is known to cause an increase of free radicals in the body. To try an combat this effect certain supplements can be used.
Vitamin C: 3000mgs in d/d
Vitamin E: 1200iu in d/d
Magnesium: 1500mgs/d
Dexatrim (or any appetite suppressant)
Glycerol 3tbsp d/d/d
