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  1. #1
    bignatt's Avatar
    bignatt is offline Anabolic Member
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    Anavar and its effect on HPTA if it exists

    This is an article from Muscular Development from the Building The Perfect Beast Column

    Q: In your books Chemical Muscle Enhancement and building the perfect beast you say anavar doesn't negativley effect the HPTA i heard about a study that proves it does in olnly a few days is this something you disagree with?

    A: Hmmm, so you feel that oxandrolone (anavar) is inhibitive to the HPTA itself? interesting. Or may it may be a matter of matter of not understating what the HPTA refers to.

    Why would anyone care if the HPTA did anything?
    The HPTA is the group of glands that directly regulates the amount of androgens and sperm the male produce The hypothalamus secretes GnRH When GnRH meets up with the pituirtary gland it tells it to release LH and FSH Then LH and FSH act as chemical messengers that tell the testes to produce androgens and sperm if we do not have androgens or sperm we do not have muscle or sex

    What directly regulates the hpta?
    For the most part we are aware that the HPTA is regulated to the greatest extent by estrogen levels in the bodys blood circulatory system and we know most anabolic androgenic steroids aromatize to estrogens to some degree or have some estrogenic nature themselves thus we use the specific degree of aromatization and the prime deciding factor in regard to HPTA supressing potential for any AAS in short more estrogen means less natural testosterone and sperm production
    Oxandrolone does not aromatize to estrogens and is therefore not directly inhibitive or suppresive to HPTA function I have monitored many hrt recipients who only used oxandrolone for prolonged periods with few exceptions these individuals maintained 60% or more normal HPTA activity since weekly LH and FSH fluctuations can sometimes be 50% +or- normal for any individual this is not a true sign of direct HPTA suppresion these individuals also have lower than normal estrogen levels due to no accumalative estrogen from aromatization with post oxandrolone use the return of normal LH and FSH is fairly quick
    LH levels decrease with non aromatizing AAS due to increased neuronet activity this is a common effect of dht and its derivatives such as oxandrolone this is not HPTA suppresion due to a true negative feedback loop but rather neuronet overload in short the HPTA stands for Hypothalamus Pituitary Testes Axis. Not to be a smart ass but there is no N for neuro-net in HPTA

  2. #2
    MMC78's Avatar
    MMC78 is offline Senior Member
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    Quote Originally Posted by bignatt
    LH levels decrease with non aromatizing AAS due to increased neuronet activity this is a common effect of dht and its derivatives such as oxandrolone this is not HPTA suppresion due to a true negative feedback loop but rather neuronet overload in short the HPTA stands for Hypothalamus Pituitary Testes Axis. Not to be a smart ass but there is no N for neuro-net in HPTA
    Wow what a smartass. In short Anavar /DHT deriviatives doesn't disrupt the HPTA in a traditional mechanism but the suppressive tendencies of these drugs remains the same.

  3. #3
    spooledup's Avatar
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    I don't feel nearly as bad when coming off a var only as I do coming off some other injectable(s). The recovery is quicker from var also.

  4. #4
    Drummerboy's Avatar
    Drummerboy is offline Anabolic Member
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    just got some var... Dragon... any opinions on dose for 200 pd male? (5mg pills, orange octagons) and 115 pd female...

  5. #5
    bignatt's Avatar
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    I just posted it because i thought it was pretty interesting

  6. #6
    Theedge's Avatar
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    30-50mg/day for Men and 5-10mg/day for women

  7. #7
    bignatt's Avatar
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    bump for jackman

  8. #8
    Drummerboy's Avatar
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    Quote Originally Posted by Theedge
    30-50mg/day for Men and 5-10mg/day for women
    thnx for the info...

  9. #9
    bignatt's Avatar
    bignatt is offline Anabolic Member
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    no problem

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