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  1. #1
    Matrix78's Avatar
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    16wk cycle Test E & Deca, should i get HCG?

    so they title about says it all, i'm goign to be running this:

    wk 1-4 Dbol 40mg
    wk 1-4 Prop 100mg ed
    wk 1-16 Test E 500mg /wk
    wk 1-16 Deca 400mg /wk
    wk 17-19 Prop 100mg ed
    Letro throughout it all
    Nolva though out it all
    B6 though out it all

    now i've been reading on here that HCG should probably be used in longer cycles and should also be used if Deca is in the cycle.. so is this considered a long cycle i'm presuming so...

    how should the HCG be run as i have no on hand experiance with it

    thanx for the help

  2. #2
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    ur cycle needs work bro
    jumpstart with either prop or dbol
    run deca til week 15 so pct lines up
    y 16 weeks of test e and deca
    how about clomid

  3. #3
    juiceinthehood's Avatar
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    whats ur experience with cycles what r ur stats whats ur goal

  4. #4
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    Quote Originally Posted by juiceinthehood
    ur cycle needs work bro
    jumpstart with either prop or dbol
    run deca til week 15 so pct lines up
    y 16 weeks of test e and deca
    how about clomid
    prop and dbol was the idea cause i just ahd another thread in here asking which on to use and i got 3 answers.. just prop, jsut dbol, and both so i figured if i got both why not use both?
    they are both 16 weeks cause its a custom blend, thats why i have prop at the end for a few more weeks
    i didnt bother writing that i was doing clomid.. i consider it a no brainer but i guess if i'm asking for help i should include everything

  5. #5
    juiceinthehood's Avatar
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    drop either the dbol or prop to start
    remember deca take 3 weeks to clear test e 2 weeks

  6. #6
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    1 gram of test a wk. is alot imo

  7. #7
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    this looks a bulker
    dbol deca test e
    why even take the prop

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    Quote Originally Posted by juiceinthehood
    this looks a bulker
    dbol deca test e
    why even take the prop
    That's a good quesion.

    I wouldn't even use the prop at all until 17-19.

  9. #9
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    Quote Originally Posted by juiceinthehood
    whats ur experience with cycles what r ur stats whats ur goal
    i've dont 2 past cycles first being a test only with dbol and winny, the second was test, eq, and tren but it just stopped mid way though due to some medical BS thats all been resolved now but it did force me to stop gym activity and protien intake for a few months and i lost anything i had ever gaind out of it so i focused on getting BF down for the past 6 months, now my goal is to pack on some serious weight and muscle and keep the BF low

  10. #10
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    use prop to finish to drop b/f get some clen

  11. #11
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    Quote Originally Posted by Matrix78
    so they title about says it all, i'm goign to be running this:

    wk 1-4 Dbol 40mg
    wk 1-4 Prop 100mg ed
    wk 1-16 Test E 500mg /wk
    wk 1-16 Deca 400mg /wk
    wk 17-19 Prop 100mg ed
    Letro throughout it all
    Nolva though out it all
    B6 though out it all

    now i've been reading on here that HCG should probably be used in longer cycles and should also be used if Deca is in the cycle.. so is this considered a long cycle i'm presuming so...

    how should the HCG be run as i have no on hand experiance with it

    thanx for the help
    What is your cycle experience? I don't think you need to jump start with both d-bol and prop. I would go with prop and drop the dbol.
    I would shoot 500iu of hcg 1x a week for weeks 2-15. Weeks 15-17 I would run hcg at 500iu eod. Make sure you stop hcg 2 weeks pior to pct.

    I just ran a similar cycle with hcg and I will start my pct in 2 weeks.

  12. #12
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    Quote Originally Posted by juiceinthehood
    this looks a bulker
    dbol deca test e
    why even take the prop
    yes its a bulker... and i dont have a problem dropping the prop at the start and jsut using it at the end thats fine, like i said it was suggested by a few to just use both so thats what i wrote out.

    but i still have the question of should i use HCG in this and if so how

  13. #13
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    Quote Originally Posted by juiceinthehood
    use prop to finish to drop b/f get some clen
    i have clen .. dont really like it, i've jsut finished 2 DNP cycles to loos BF so i'm not to concernd about gaining some back during this cycle

  14. #14
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    Yup you should. Use 500iu E3D from week 7 or 8. You could run it all the way thru as well if you wanna. Be sure to stop it before PCT. Good luck!

  15. #15
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    eat clean bro

  16. #16
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    Quote Originally Posted by fitnessNY
    What is your cycle experience? I don't think you need to jump start with both d-bol and prop. I would go with prop and drop the dbol .
    I would shoot 500iu of hcg 1x a week for weeks 2-15. Weeks 15-17 I would run hcg at 500iu eod. Make sure you stop hcg 2 weeks pior to pct.

    I just ran a similar cycle with hcg and I will start my pct in 2 weeks.
    thanx for the info on the HCG thats what i'm looking for, and now you can see why i'm confused as far as a jump start i have one side saying dbol the other saying prop... i just dont knwo which side to take

  17. #17
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    Quote Originally Posted by juiceinthehood
    eat clean bro
    i am now, my diet had always sucked in the past and now i'm planning all my food out ahead of time jsut like my cycle so i can keep on track pre buying anything i can to ensue i always have everything i need on hand for my diet.. i wana eat like a one man army jsut eat all the right stuff

  18. #18
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    I disagree with fitnessNY...
    And oh...be sure to have some bromo at hand as well when running deca ...

  19. #19
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    Quote Originally Posted by youknowme
    I disagree with fitnessNY...
    And oh...be sure to have some bromo at hand as well when running deca...
    yes bromo is a must for deca good call bro
    take a look at swales hcg protocal do a search on it

  20. #20
    Matrix78's Avatar
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    thanx for the info all

  21. #21
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    Quote Originally Posted by juiceinthehood
    yes bromo is a must for deca good call bro
    take a look at swales hcg protocal do a search on it
    thanx i found that thread alot of good info in there

  22. #22
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    Quote Originally Posted by Matrix78
    thanx i found that thread alot of good info in there
    good luck bro

  23. #23
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    Quote Originally Posted by Swale's PCT protocol
    I advise my AAS patients to use small amounts of HCG (250IU to 500IU) two days each week, right from the beginning of the cycle. This serves to maintain testicular form and function. It makes more sense to me to keep the horse in the barn, so to speak, then to have to chase it across three counties later on. I am also a big fan of maintaining estrogen within physiological ranges. Both therapies have been shown to hasten recovery.
    so will most people around here agree with the 500iu 2x per week throught the entier cycle would be best when using Deca and havign a longer cycle? thats what i got from reading this write up on HCG or did i get it wrong?

  24. #24
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    bump just for good measure and to make sure I just got everything right

    from what i've found my best bet would be something around 500iu 2x per week,
    so 1000iu per week...
    at 16 weeks and, if i start HCG on week 2, i'll need a total of...
    15,000iu which would be one full "box" (3 5000iu amps)

    yes / no?

  25. #25
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    Yeah I'm running the same cycle also..15 weeks with a jump of prop.......shiaat I never thought about running hcg .....is it a must

  26. #26
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    The Axis



    The Hypothalamic-Pituitary-Testicular Axis, or HPTA for short, is the thermostat for your body’s natural production of testosterone . Too much testosterone and the furnace will shut off. Not enough, and the heat is turned up, to put it very simply. For the purposes of our discussion here we can look at this regulating process as having three levels. At the top is the hypothalamic region of the brain, which releases the hormone GnRH (Gonadotropin-Releasing Hormone) when it senses a need for more testosterone. GnRH sends a signal to the second level of the axis, the pituitary, which releases Luteinizing Hormone in response. LH for short, this hormone stimulates the testes (level three) to secrete testosterone. The same sex steroids (testosterone, estrogen) that are produced serve to counter-balance things, by providing negative feedback signals (primarily to the hypothalamus and pituitary) to lower the secretion of testosterone when too much of this hormone is sensed. Synthetic steroids, of course, suppress testosterone the same way. This quick background of the testosterone-regulating axis is necessary to furthering our discussion, as we need to first look at the underlying mechanisms involved before we can understand why natural recovery of the HPTA post-cycle is a slow process. Only then can we implement an ancillary drug program to effectively deal with it.



    Testicular Desensitization


    Although steroids suppress testosterone production primarily by lowering the level of gonadotropic hormones discussed above, the big roadblock to a restored HPTA after we come off the drugs is surprisingly not the level of LH itself. This problem is made clearly evident in a study published in Acta Endocrinologica back in 1975(1). Here blood parameters, including testosterone and LH levels, were monitored in male subjects whom were given testosterone enanthate injections of 250mg weekly for 21 weeks. Subjects remained under investigation for an additional 18 weeks after the drug was discontinued. At the start of the study, LH levels became suppressed in direct relation to the rise in testosterone, which is to be expected. Things looked very different, however, once the steroids had been withdrawn (see Figure I). LH levels went on the rise quickly (by the 3rd week), while testosterone barely budged for quite some time. In fact, on average it was more than 10 weeks before any noticeable movement started. This lack of correlation makes clear that the problem in getting androgen levels restored is not the level of LH, but in fact testicular atrophy and desensitization to this hormone. After a period of inactivation the testes have apparently lost mass (atrophied), making them unable to perform the workload required by heightened levels of LH.


    Post-Cycle LH Levels


    Post Cycle Testosterone Levels



    Figure I. LH and Testosterone measurements starting 1 week after the last injection of 250mg of testosterone enanthate (pretreated measures were 5 mU/ml and 4.5 ng/ml respectively). Note that between weeks 1 and 5, as testosterone levels are declining due to the cessation of exogenous androgen administration, LH levels are already rebounding. From weeks 5 to 10 testosterone levels are at or very near baseline, to spite the substantial LH levels by this point. No significant increase in testosterone is noted until after the 10-week mark.



    The Role of Anti-estrogens


    It is important to understand that anti-estrogens alone do not do much to restore endogenous testosterone release after a cycle. Normally they only foster LH by blocking the negative feedback of estrogens, and we now see that LH rebounds quickly without help anyway. Plus, post cycle there is not an elevated level of estrogen for anti-estrogens to block, as testosterone (now suppressed) is a major substrate used for the synthesis of estrogens in men. Serum estrogen levels will actually be lower here as a result, not higher. Any estrogen rebound that occurs post-cycle likewise happens concurrently with a rebound in testosterone levels, not prior to it (note there is an imbalance in the ratio post cycle, but this is another topic altogether). We are seeing no mechanism in which anti-estrogenic drugs can really help here. We can see why this fact would not be difficult to overlook, however. The medical literature is filled with references showing anti-estrogenic drugs like Clomid and Nolvadex to increase LH and testosterone levels, and in normal situations these drugs do indeed increase endogenous androgen production by blocking the negative feedback of estrogens. Combine this with the fact that just as many studies can be found to show that steroid use lowers LH levels when suppressing testosterone, and we can see how easy it would be to jump to the conclusion that post-cycle we need to focus on restoring LH. We would miss the true problem of testicular desensitization unless we were really looking into the actual recovery rates of the hormones involved. When we do, we immediately see little value in using anti-estrogenic drugs.



    HCG


    So we now see, contrary to the dominating opinion of the times, that anti-estrogens alone will do little to raise testosterone levels in the early weeks of the post-cycle window. This leaves us to focus on a very different level of the HPTA in order to hasten recovery: the testes. For this we will need the injectable drug HCG. If you are not familiar with it, HCG, or Human Chorionic Gonadotropin , is a prescription fertility agent that mimics the bodies own natural LH. Although the testes are equally desensitized to this drug as LH (they both work through the same mechanism), we are administering it as a measured drug and are therefore not constrained by the limits of our own LH production. We similarly can use HCG to provide a bolus dose of LH (of our choosing), which works only to augment the recovering LH levels we already have in the body. In essence we are looking to shock them with an overwhelmingly high level of LH activity, coming from both endogenous and exogenous sources. We want it to reach a level far above what our body, even when supported by anti-estrogens, could possibly do on its own. The result can be a rapid restoration of original testicular mass and functioning, which would allow normal levels of testosterone to be output much sooner than without such an ancillary program. What we are looking at now is HCG actually being the pivotal post-cycle drug, while anti-estrogens are relegated to a supportive role at best.



    Finalizing the Program


    An ideal post-cycle recovery program will focus on two things really. The first is hitting the testes hard with HCG. It is important, however, not to overuse this drug. Taken for too long, or at too high a dosage, the LH receptor will actually become desensitized to LH(2) , which may further exacerbate our post-cycle problem instead of helping it (this is why I am not in favor of regular HCG use on-cycle). My experience with HCG has led me to feel comfortable using it for a course of three weeks, at a dosage of maybe 5000-7500IU weekly. Often the last week I limit the dose to 2,500IU, unless the cycle has been particularly long or potent. This is timed so at least half of the total administered drug dosage will be given when there is still exogenous steroid in the body. On our graph above this would be at about the 3-week mark after the last injection of testosterone. This will give the testes some time to get back into shape before the baseline is actually hit with T levels. Secondly, Anti-estrogens are used to play a supportive role at the same time, so 20mg of Nolvadex or 50-100mg of Clomid would typically be added ( my last article for Mind and Muscle discusses the comparative differences with these two agents). This is to combat the suppressive effects of estrogen as testosterone levels start to go back up, as well as potential side effects (HCG has been shown to increase testicular aromatase activity as well (3)). Although in the first couple of weeks the anti-estrogen does little, it may indeed be helpful when testosterone levels actually start to get back up near normal. To further stimulate the HPTA, and support continuingly high LH levels, the anti-estrogen remains to be used for 2 to 3 weeks after the HCG therapy has been stopped. A sample program, as it would be instituted in our sample post-cycle window, is provided below.



    Sample Post-cycle Plan:


    Week 3: 5000IU HCG total + 20mg Nolvadex daily
    Week 4: 5000IU HCG total + 20mg Nolvadex daily
    Week 5: 2500IU HCG total + 20mg Nolvadex daily
    Week 6: 20mg Nolvadex daily
    Week 7: 20mg Nolvadex daily
    Week 8: 20mg Nolvadex daily



    In Closing


    I hope this article provided a well-needed new look at the mechanisms involved in post-cycle testosterone recovery. Indeed I believe it should debunk a commonly held belief these days, as we seen now that those advocating the sole use of Clomid post cycle are sorely missing the mark. The problem goes much deeper than just getting LH levels back. In fact, we see that LH doesn’t even need much help kicking back into gear, and a drug like Clomid will do very little to help this anyway in the absence of significant estrogen levels anyway. HCG is a drug with undeniable usefulness during the post-cycle window, and many bodybuilders have been much too quick to abandon it. It is truly fundamental to an effective recovery program, and would not consider any dose or combination of anti-estrogens or aromatase inhibitors capable of doing the job without it.


    References:

    1. Effect of long-term testosterone oenanthate administration on male reproductive function: Clinical evaluation, serum FSH, LH, Testosterone and seminal fluid analysis in normal men. J. Mauss, G. Borsch et al. Acta Endocrinol 78 (1975) 373-84

    2. Desensitization to gonadotropins in cultured Leydig tumor cells involves loss of gonadotropin receptors and decreased capacity for steroidogenesis. Freeman DA, Ascoli M Proc Natl Acad Sci U S A 1981 Oct;78(10):6309-13

    3. Acute stimulation of aromatization in Leydig Cells by Human Chorionic Gonadotropin In-vitro. PrBy William Llewellyn

  27. #27
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    Thank you Bignatt!!

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    no problem man

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