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  1. #1
    Cuttup's Avatar
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    BEST way to do T4 Synthroid while on Test E

    Vets and those of experience,

    Im sitting on a sh@t load of T4. Im in the 5th week of my cycle and would like to throw this in. I know t3 is better(i have that too for next cycle) but since this is my first go around using a thyroid suppplement...t4 is ideal. what is the suggested dose,..how long can i stay on it,..dosings all at once or broken up through out the day? Thanks.

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    bump

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    search for a thread from mallet on this
    i believe its 7days on 5days off

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    a post from mallet at our site

    T4 is a little trickier to dose..the rule of thumb is four times as much t4 to t3, basically your body produces about 75mcg a day of t4 and roughly one third of that is converted to t3 (25mcg). t3 is four times more active than t4 at the target cells. The main difference between taking t4 and taking t3 is you have no control of the conversion rate of t4 to t3, so it's imparitive that your diet be high in Selenium (200mcg) and zinc (50mg) without selenium and zinc, the enzyme iodothyronine deiodinase cannot do its job of converting t4 to t3. One enzyme that is particularily of interest is adenylate cyclase, this enzyme activates the molecule cyclic adenosine monophosphate (cAMP)supplementing with Coleus Forskolii will help with cAMP. T4 has a slower onset of endogeous shutdown, therefore cycling can be slightly longer without breaking. The answer still lies in monitoring your basal body temp every morning to see how your metabolism is responding to the supplementing of thyroid hormones. The half life of t4 is shorter as well due to the fact that a percentage of t4 is readily converted to t3, so splitting up your dose throughout the day is recommended!

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    Quote Originally Posted by juiceinthehood
    a post from mallet at our site

    T4 is a little trickier to dose..the rule of thumb is four times as much t4 to t3, basically your body produces about 75mcg a day of t4 and roughly one third of that is converted to t3 (25mcg). t3 is four times more active than t4 at the target cells. The main difference between taking t4 and taking t3 is you have no control of the conversion rate of t4 to t3, so it's imparitive that your diet be high in Selenium (200mcg) and zinc (50mg) without selenium and zinc, the enzyme iodothyronine deiodinase cannot do its job of converting t4 to t3. One enzyme that is particularily of interest is adenylate cyclase, this enzyme activates the molecule cyclic adenosine monophosphate (cAMP)supplementing with Coleus Forskolii will help with cAMP. T4 has a slower onset of endogeous shutdown, therefore cycling can be slightly longer without breaking. The answer still lies in monitoring your basal body temp every morning to see how your metabolism is responding to the supplementing of thyroid hormones. The half life of t4 is shorter as well due to the fact that a percentage of t4 is readily converted to t3, so splitting up your dose throughout the day is recommended!
    wow,..thanks alot....hats pretty deep...

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    Quote Originally Posted by juiceinthehood
    a post from mallet at our site

    T4 is a little trickier to dose..the rule of thumb is four times as much t4 to t3, basically your body produces about 75mcg a day of t4 and roughly one third of that is converted to t3 (25mcg). t3 is four times more active than t4 at the target cells. The main difference between taking t4 and taking t3 is you have no control of the conversion rate of t4 to t3, so it's imparitive that your diet be high in Selenium (200mcg) and zinc (50mg) without selenium and zinc, the enzyme iodothyronine deiodinase cannot do its job of converting t4 to t3. One enzyme that is particularily of interest is adenylate cyclase, this enzyme activates the molecule cyclic adenosine monophosphate (cAMP)supplementing with Coleus Forskolii will help with cAMP. T4 has a slower onset of endogeous shutdown, therefore cycling can be slightly longer without breaking. The answer still lies in monitoring your basal body temp every morning to see how your metabolism is responding to the supplementing of thyroid hormones. The half life of t4 is shorter as well due to the fact that a percentage of t4 is readily converted to t3, so splitting up your dose throughout the day is recommended!
    wow,..thanks alot....thats pretty deep...

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