First of all, i would like to say even though this is my first post on this site that I have been coming here for about a two years nowjust never really bothered to become a member... Anyway, I had a lil gyno after a cycle so I got some letro(for my rat). Now some says it works while others don't so i decided to seek the help of my uncle who is a Dr. He manages a Medical Lab center as well (does research/experiments ..etc) After our talk, I began with the letro. Started w/ two or three pumps a day for 4 days. then took my uncles advice and APPLIED THE LETRO DIRECTLY ON THE SKIN TO and AROUND THE NIPPLE. The skin absorbed it well and now within an week and a 1/2 the gyno is a whole lot smaller and is not as solid! NOT as sensitive either... and I still basically have a whole bottle left... All I am sayin is that if you are undecided on using Letro, IT WORKED for me! and that if it stopped today i am still satisfied w/ the results it has given. Also I am also workin my chest out hard to though...but i will continue to update the process on my rat.