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  1. #1
    MotoLifter's Avatar
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    New Clomid Profile for Our Site, Please comment!

    The structural diagram didnt come out. I dont think it was imperative to the profile. Spelling will be done w/ other corrections as advised. Thanks.

    Clomiphene Citrate better known as Clomid, has been used by males and females although for differing purposes for many years. Clomid is the brand name patented by Merell Dow Research Institute. Clomid was originally developed for use in women who desired to become pregnant. It is a non anabolic steroid , however does require a prescription. Clinically speaking Clomid opposes the negative feedback of estrogens on the HPOA (hypothalamic-pituitary-ovarian axis), which in turn enhances the release of FSH (follicle stimulating hormone) and LH (Luteinizing hormone) helping to facilitate pregnancy. Dosing will vary from person to person. The average dose for treating infertility is 50mg a day for five days of a menstrual cycle, typically started on the fifth day. If pregnancy is not achieved the dosage may be increased slowly up to 250mg a day.

    Clomiphene Citrate is designated chemically as:
    2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]triethylamine citrate(1:1)

    Clomiphene Citrate is a mixture of two geometric isomers: [cis(zuclomiphene) and trans(enclomiphene)] usually containing between 30% and 50% of the cis-isomer. Each 50mg tablet also contains the following inactive ingredients: corn starch, lactose, magnesium stearate, pregelatinized corn starch, and sucrose.

    It is represented structurally as:


    Its molecular formula is: C26 H28 CINO ( C 5 H 8 O 7

    With a molecular weight of 598.09.

    Clomiphene Citrate is freely soluble in ethanol, methanol, slightly soluble in acetone, water, and chloroform, and is insoluble in ether.


    For athletic purposes Clomid is used to elevate natural testosterone production by increasing the bodies levels of both FSH and LH. Clomid seems to be most beneficial to a male athlete at the conclusion of a steroid cycle, when endogenous testosterone levels are significantly decreased. Should the body’s natural testosterone not be aided in returning to normal levels a major loss in size and strength will almost certainly occur after the anabolics have been stopped. The cause of these loses in size and strength is do to the catabolic hormone cortisol, which becomes the overwhelming hormone affecting muscle protein synthesis, at the time when endogenous testosterone levels are depressed. This catabolic state is known as the “post-cycle crash”, and can quickly eat away much of your hard earned muscle. Clomid plays a crucial role in preventing this “crash”. There is a small but loyal following of people who use small doses of Clomid during anabolic steroid cycles in the hopes of keeping endogenous testosterone levels from falling to far of the spectrum. Studies have, as of yet not determined a benefit or detriment regarding these practices. Many people also use HCG in conjunction with Clomid. This practice is not recommended and can lead to the desensatizing if the testes, and in some cases semi permanent shut down of the testes. As far as females are concerned Clomid’s only real use is for pre-contest control of endogenous estrogen levels. This type of administration can increase muscularity and fat loss especially in female trouble areas (hips, thighs).
    Since Clomid is a synthetic estrogen but with only mild estogenic properties, it binds to receptor sites inhibiting the ability of stronger estrogens such as those that form from the aromatization of steroids from binding to those same sites. A common misconception is that Clomid prevents steroids from aromatizing, this idea is false it simply deactivates stronger estrogens by blocking receptor sites.

    Common Clomid post cycle therapy (PCT) courses are as follows:
    Day 1 300mg
    Day 2-11 100mg/day
    Day 12-21 50mg/day

    Pheedno’s PCT, courtesy of Anabolic Review: Post Cycle Therapy Forum

    PCT for cycles 8-16wks:
    Day 1-30- .25mg L-dex + 100mg Clomid + 20mg Nolva

    Extended protocol sample for a 12+ month cycle:
    Day 1-15_ .25mg L-dex + 100mg Clomid + 20mg Nolva
    Day 16-45_.25mg L-dex + 75mg Clomid + 20mg Nolva
    Day 46-65_.25mg L-dex + 20mg Nolva
    Day 66-80_.25mg L-dex

    Clomid is only beneficial if it is used after the active life of the compounds you have taken have your the system. This is critical to restoring normal testosterone levels. PCT start times are as follows:

    Pheedno’s PCT start times, courtesy of Anabolic Review: Post Cycle Therapy Forum

    Anadrol /Anapolan: 24 hours after last administration
    Deca : 21 days after last injection
    Dianabol : 24 hours after last administration
    Equipoise : 21 days after last injection
    Fina: 3 days after last injection
    Primobolan depot: 14 days after last injection
    Sustanon : 18 days after last injection
    Testosterone Cypionate : 18 days after last injection
    Testosterone Enanthate : 14 days after last injection
    Testosterone Propionate : 3 days after last injection
    Testosterone Suspension : 24 hours after last administration
    Winstrol : 24 hours after last administration





    Clomid is not detected though conventional drug tests due to the fact that it is neither a narcotic nor a steroid. However its affects are readily apparent when having blood analyzed for testosterone production, or normal testes function.
    There are no known drug interactions with clomiphene citrate. Clomid is considered a very safe drug as far as toxicity and side effects are concerned. Weightlifters rarely report any problems but possible side effects include; hot flashes, dizziness, headaches and temporary blurred vision. Females are the overwhelming majority demographic who report these symptoms, most likely do to the fact that the feel the effects of estrogen manipulation in a much more pronounced fashion than males. Prolonged use results in elevated serum levels of desmosterol, most likely due to the interferance of Clomid with cholesterol synthesis.


    Incidence of Adverse Events In Clinical Studies
    (Events greater than 1%)
    (n=8029*) Adverse Event %
    Vasomotor flush 13.6
    Abdominal-Pelvic
    Discomfort/
    Bloating/Distention 5.5
    Nausea/Vomiting 2.2
    Breast Discomfort 2.1
    Visual Symptoms
    Blurred vision,
    Lights, Floaters,
    Waves, Photophobia 1.5
    Headache 1.3
    *Includes 498 patients whose reports may have been duplicated in the event totals and could not be determined as such. Also, exclude 47 patients who did not report symptom data.

    Less than 1% reported:

    Dermatologic reactions; acne, allergic reaction
    Central Nervous System; migraines, seizure, stroke
    Psychiatric; anxiety, irritability, mood changes, psychosis
    Visual; abnormal accomidation, cataract, eye pain, retinal hemorrhage, retinal vascular spasm, temporary loss of vision
    Cardiovascular; chest pain, palpitation, shortness of breath
    Body as a Whole; fever, tinnitus, weakness


    Tolerance, abuse or dependence with Clomid has not been reported. Toxic affects with acute overdosing of Clomid have not been reported. Symptoms of overdosing during Clomid therapy include but are not limited to: nausea, vomiting, visual blurring, and abdominal pain.



    Manufacturers include:
    Substance: clomiphene citrate
    Trade Names: Error! Hyperlink reference not valid.Error! Hyperlink reference not valid.
    Ardomon 50 mg tab.; Med-Hel GR
    Clom 50 (o.c) 50 mg tab.; Salutas G
    Clomid 50 mg tab.; Merell Dow B,CH,U.S.; Merell FR,GB;Lepetit I; Haus
    Clomifen 25 mg cap.; Lab Casen ES
    Clomifen 50 mg tab.; Leiras F1
    C.-ratioph. (o.c) 50 mg tab.; Ratiopharm G
    Clomiphen Citrate 50 mg tab.; Anfarm GR
    Clomiphen-Merck 50 mg tab.; Merck A
    Clomipheni citras 50 mg tab.; Centrafarm NL
    Clomivid 50 mg tab.; Draco DK, 5
    Clostilbegyt 50 mg tab.; Egis HU, Bulgaria
    Clostilbegyt 50 mg tab.; Medphano G
    Clostilbegyt (o.0 G 50 mg tab.; Med Pharm G, Thiemann
    Dufine 50 mg tab.; Inibsa PT
    Dyneric 50 mg tab.; Marion Merrell Dow G
    Gravosan 50 mg tab.; Leciva CZ
    Indovar 50 mg tab.; Jaba PT
    Klomifen 50 mg tab.; Belupo YU; Mulda TK; Yurtoglu TK
    Kyliformon 50 mg tab.; Kylifor GR
    Omifin 50 mg tab.; Merrell ES, Mexico
    Pergotime 50 mg tab.; Icapharm S; Serono G, DK, F9, Serono/Zyma-Golen Be
    Pioner 50 mg tab.; Remedina GR
    Prolifen 50 mg tab.; Chiesi I
    Serofene 50 mg tab.; Serono Argentina, Mexico
    Serophene 50 mg tab.; Interlabo CH; Pharma-Im- port NL; Serono GB, U.S.,
    Serpafar 50 mg tab.; Faran GR, BG
    Tokormon 50 mg tab.; Genepharm GR

    (the above was the table that is currently in the Clomid profile)


    Clomiphene Citrate is widely available on today’s black market, in a wide variety of brand names and often generic verions as well. The brand name varieties can be very expensive running as high as 2$-4$ per 50mg tablet. Generics such as those made by Anafarm in Greece are easily obtained and sell for much less. In the U.S. Omifin from Mexico seem to be growing in popularity. Due to the lack of counterfeits Clomid has been and most likely will continue to be a safe buy on the black market.


    References:
    www.drugs.com/PDR/Clomid_Tablets.html
    www.anabolicreview.com
    www.pubmed.com
    A well respected Harvard Med. School Grad, who wishes to remain nameless.
    Last edited by MotoLifter; 10-01-2004 at 01:16 PM.

  2. #2
    moush's Avatar
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    great job bro i hope i can do as well as your profile...

  3. #3
    system admin is offline Owner
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  4. #4
    MotoLifter's Avatar
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    hey bumpbump, not too much info here.

  5. #5
    bd50's Avatar
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    great post,, thanks bro

  6. #6
    MotoLifter's Avatar
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    anyone else???????

  7. #7
    MaNofSteeL is offline Associate Member
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    good but not enough info.

  8. #8
    BigGenes's Avatar
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    Looks good bro.

  9. #9
    MotoLifter's Avatar
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    Bump for more opinions...

  10. #10
    KGBnine is offline Anabolic Member
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    looks good. not exhaustingly long. I think it has all the important info and no BS.Good job.

  11. #11
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    Kinky post!!!!!! two thumbs up

  12. #12
    wired-up's Avatar
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    great info.

  13. #13
    MotoLifter's Avatar
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    thanks everyone. worked pretty hard on this, didnt wanna let everyone down. Any other ideas, opinions, comments, questions........?

  14. #14
    Unknown$$ is offline Associate Member
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    bump for more input

  15. #15
    MotoLifter's Avatar
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    Annnnnnndddddd up we go!!!!

  16. #16
    MotoLifter's Avatar
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    bump

  17. #17
    MotoLifter's Avatar
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    Again for more info. (Admin request)

  18. #18
    dellrugby is offline Junior Member
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    I am just on my first week of Sust and EQ, and have tender nips. so I am taking 50 MG a day to see if that goes away. Will let you know how that goes..

  19. #19
    50%Natural's Avatar
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    Quote Originally Posted by dellrugby
    I am just on my first week of Sust and EQ, and have tender nips. so I am taking 50 MG a day to see if that goes away. Will let you know how that goes..
    why?

  20. #20
    seanw's Avatar
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    50 mg of what, not clomid I hope. You should be taking Nolvadex

  21. #21
    tycin's Avatar
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    Quote Originally Posted by dellrugby
    I am just on my first week of Sust and EQ, and have tender nips. so I am taking 50 MG a day to see if that goes away. Will let you know how that goes..
    that wont fix the problem bro! try 40mg of nolva.

  22. #22
    meat is offline Associate Member
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    i dont get it,i dont get it,......JK bro good work

  23. #23
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    GREENMACHINE is offline Are you green enough?
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    Awesome post brutha very informative but not clinically so. Nice job.

  24. #24
    RockStar69 is offline New Member
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    What is L-dex??

  25. #25
    wired-up's Avatar
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    Quote Originally Posted by RockStar69
    What is L-dex??
    here's some good info on it

  26. #26
    Swifto's Avatar
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    Some good info, an educational thread

  27. #27
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    great job Moto

  28. #28
    SS1476's Avatar
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    Well...as a "newbie", I like to read and read (only here)...
    and for me, its a good read, and further expanded
    my knowledge on Clomid.

    Thanks

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