Roaccutane (Accutane) has shown to alter brain function in all teenagers that were scanned after exposure to the toxin. Roaccutane also is found to lower the levels of several hormones such as thyroid hormone, growth hormone and dihydrotestosterone, which is likely to give problems later in life, because the hormonal levels fall naturally. Roaccutane is an irreversible antiandrogen substance. Roaccutane is taken in a 100 times daily overdose of vitamin A – for several months. Because it is so toxic, it is used in cancer patients against tumours. One type of cancer where it is used is glioblastoma, a type of brain cancer.

For further information:

Picture 1. Bremner JD et al. Functional brain imaging alterations in acne patients treated with isotretinoin. (2005) Am J Psychiatry. May;162(5):983-91.

Roaccutane is found to have at least around 50 known side-effects including severe eye related disorders.

Picture 2. Lissamine green corneal staining of a dry eye patient taking isotretinoin. Photo courtesy of Eric Donnenfeld, M.D.

Whatever you take - do not take Accutane!