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  1. #1
    powerliftmike's Avatar
    powerliftmike is offline AR-Hall of Famer
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    Difference in progesterone and estrogen?

    I have read about Deca and Anadrol converting to progesterone, while Test and Dianabol reduce to estrogen. What are the differences in these hormones and their effects?

  2. #2
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    Quote Originally Posted by powerliftmike
    I have read about Deca and Anadrol converting to progesterone, while Test and Dianabol reduce to estrogen. What are the differences in these hormones and their effects?
    nothing can convert to progesterone. they can however activate the progesterone receptor (ie deca and tren ) drol "supposedly" activates estrogen receptors.

  3. #3
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    Wolfy is correct re: Deca and Tren . They are progestins, meaning they stimulate the PgR.

    Drol actually inhibits progesterone secretion, and we don't know that it converts to estrogen at all, since it is derived from DHT, and DHT is structurally incapable of aromatization. There is, however this (bizarre and unique) alteration at the second position, that would appear to give 'drol the ability to stimulate the estrogen receptor (?)...maybe....possibly....even be removed eventually to go back to being DHT?

    I can't really comment fully on the 2-hydroxymethylene group, and I really doubt anyone can, to be honest....with any real hard facts, anyway....

  4. #4
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    Institut fur Pharmazeutische Chemie, Technischen Universitat Braunschweig.

    A-ring annulated heterocycles, the isoxazole 6, the pyrazoles 8 and the pyrimidines 9 are prepared starting from 2-hydroxymethylene canrenone 1. Binding studies were carried out with the compounds 1 and 6-8 using estrogen, progesterone, androgen, gluco- and mineralocorticoid receptors as well as the serum proteins SHBG and CBG: the substances were inactive on the receptor level. 1, 7 and 8a show weak binding affinity to CBG.

    an article I saw

  5. #5
    J.S.N.'s Avatar
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    basically the layman's skinny is:

    progresterine problems are alot harder to clear up.
    Last edited by Prince Myshkin; 08-31-2005 at 03:08 PM.

  6. #6
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    Quote Originally Posted by Prince Myshkin
    basically the layman's skinny is:

    progresterine problems are alot hardest to clear up.
    Yea, what the prince said.. LOL. Thanks Prince

  7. #7
    J.S.N.'s Avatar
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    Wink

    Quote Originally Posted by big_C
    Yea, what the prince said.. LOL. Thanks Prince

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