Originally Posted by hooker
Here's the highlights of the studies:
Dowsett M., Pfister C., Johnson S. R. D., Miles D. W., Houston S. J., Verbeek J. A. Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer. Clin. Cancer Res., 5: 2338-2343, 1999.
The ATAC Trialists’ Group. Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the "Arimidex and Tamoxifen Alone or in Combination" (ATAC) trial. Br. J. Cancer, 85: 317-324, 2001
Clinical Cancer Research Vol. 10, 372S-379S, January 2004