Anabolics
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  1. #1
    bex's Avatar
    bex
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    Please Read do steroids cause muscle and body growth?

    Do steroids cause muscle and body growth?

    There is no evidence that ultra-high doses of steroids alone
    will cause muscle growth through a chemical effect. In many animal
    species, high doses of anabolic steroids produce no more muscle
    growth than the normal dose would However, there
    is evidence that steroids enhance muscle growth if taken along with
    rigorous physical training and a high protein diet.This
    exercise program must be in place before and during anabolic
    steroid administration.

    Anabolic steroids act on the balance between anabolic and
    catabolic processes within the body. Anabolism is the constructive
    process by which simple substances are converted to more complex
    compounds, such as bone and muscle tissue. Catabolism is the
    corresponding destructive process which breaks down these complex
    compounds for removal from the body. The normal body will attempt
    to maintain a balance between these two processes as they carry out
    tissue renewal and replacement. The state of anabolism
    and catabolism may be measured by evaluating the body's nitrogen



    balance.

    As Stedman's Medical Dictionary puts it:

    [Nitrogen balance is] the difference between total nitrogen
    ingested and the total nitrogen excreted by an organism. In
    an adult, presumably not growing, this should be zero at a
    given intake or above.

    Anabolic steroids reverse the catabolic effect by increasing
    protein synthesis in skeletal muscle.They are
    believed to diffuse into the cellular cytosol and bind to the
    androgen receptor. The newly formed receptor-steroid complex
    migrates to the nucleus, interacts with the DNA and initiates
    transcription. The production of RNA is then increased, causing an
    increased rate of protein synthesis. In this way, the use of these
    agents increases muscle size and strength.

    In order for the athlete to accumulate extra muscle mass, his
    or her body must temporarily be in a state of positive nitrogen
    balance: More nitrogen (as muscle mass) must come into the body
    than is lost. During strenuous exercise, the release of
    glucocorticosteroids throws the body into a negative nitrogen
    balance. After exercise, the body experiences a temporary state
    of positive nitrogen balance, during which new proteins are added
    to muscle tissue. Unless there is further exercise, the nitrogen
    balance returns to zero.

    Without the use of anabolic steroids, muscle mass is built up
    very slowly after long periods of rigorous training. Anabolic
    steroids can reverse the short-term catabolic effect, leading to
    positive nitrogen balance and faster gains in muscle mass.
    However, maintenance of a positive nitrogen balance is short lived
    (1 - 2 months) unless the steroid dose is continually increased.
    Rapid tolerance (tachyphylaxis) to steroids occurs in muscle tissue
    as the body attempts to maintain homeostasis.One
    homeostatic mechanism may be a rise in serum cortisol during
    steroid treatment. This may counteract the anabolic effect while
    potentiating the catabolic.The risk of serious side
    effects is increased as the athlete takes higher and higher doses
    of anabolics to maintain a positive nitrogen balance.

    There is some evidence that anabolic steroids cause the
    athlete to feel like working out more often and more
    vigorously.This psychological effect may be more
    important than any direct chemical effect.Frequent and
    more vigorous workouts may be a reason for the increased incidence
    of connective tissue injuries associated with steroid
    abuse.

    REFERENCES

    1. Wilson JD. Androgen abuse by athletes. Endocrine Reviews
    1988;9(2):181-99.

    2. Strauss RH. Anabolic steroids. In: ed. Drugs and performance
    in sports. Philadelphia: WB Saunders, 1987:5, 59-67.

    3. Wagner JC. Abuse of drugs used to enhance athletic
    performance. American Journal Of Hospital Pharmacy 1989
    Oct;46:2059-67.

    4. Kibble MW, Ross MB. Adverse effects of anabolic steroids in
    athletes. Clinical Pharmacy 1987 Sep;6:686-92.

    5. Kleiner SM. Performance-enhancing aids in sport - health
    consequences and nutritional alternatives. J Amer Coll Nutr
    1991 Apr;10(2):163-76.

    6. Daigle RD. Anabolic steroids. J Psychoactive Drugs 1990 Jan-
    Mar;22(1):77-80.

    7. Smith DA, Perry PJ. The efficacy of ergogenic agents in
    athletic competition. part 1: androgenic -anabolic steroids.
    Annals Pharmacother 1992 Apr;26:520-8.

    8. Stedman TL. Stedman's Medical Dictionary. Baltimore: Williams
    & Wilkins, 1976.

    9. Windsor R, Dumitru D. Prevalence of anabolic steroid use by
    male and female adolescents. Med Sci Sports Exercise 1989
    Oct;21(5):494-7.

    10. Yesalis CE, Wright JE, Bahrke MS. Epidemiological and policy
    issues in the measurement of the long term health effects of
    anabolic-androgenic steroids. Sports Medicine 1989
    Sep;8(3):129-38.
    Last edited by bex; 05-12-2002 at 04:51 PM.

  2. #2
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    good read...

  3. #3
    Wimmpy is offline Associate Member
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    Interesting

  4. #4
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    bump, good post bex!

  5. #5
    Ajax's Avatar
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    Originally posted by bex
    There is some evidence that anabolic steroids cause the
    athlete to feel like working out more often and more
    vigorously.This psychological effect may be more
    important than any direct chemical effect.Frequent and
    more vigorous workouts may be a reason for the increased incidence
    of connective tissue injuries associated with steroid
    abuse.
    Ummm, sounds like they had somebody with no knowledge of steroids write up a few quick paragraphs for a magazine on Men's Lifestyles. The last paragraph is so obviously bullsh*t it makes the rest of the article suspect as well.

    By the way Bex: "Read This" is really a poor subject line for a post--please be more specific if you can! Not a slam--just helpful advice!

    Ajax: member of the subject line enforcement squad!
    Last edited by Ajax; 05-12-2002 at 03:42 PM.

  6. #6
    Microbrew's Avatar
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    Agree with ajax!!

  7. #7
    bex's Avatar
    bex
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    Originally posted by Ajax

    Ummm, sounds like they had somebody with no knowledge of steroids write up a few quick paragraphs for a magazine on Men's Lifestyles. The last paragraph is so obviously bullsh*t it makes the rest of the article suspect as well.

    By the way Bex: "Read This" is really a poor subject line for a post--please be more specific if you can! Not a slam--just helpful advice!

    Ajax: member of the subject line enforcement squad!
    What is this Mr ajax i hope it is not a flame Now that would offend me..
    Of course i nearly forgot you must be the only one that has so much knowlage that there is no need for me to post anythink else on the board
    because we only need you..MEET AJAX THE NEW MOD......................
    (Iam in a bad mood as it is so i will say good bye)

  8. #8
    bex's Avatar
    bex
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    I have put the references on for you which i forgot in the original post...

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