Thread: AA-17 question
11-08-2001, 04:58 PM #1
Does anyone have any clue as to whether or not this compound has any effects itself on the body as a negetive or is it just the agents carried by this component .... ?
11-08-2001, 05:25 PM #2Mike Guest
17aa is not a "compound" per se......tricky answer really - but steroids that have been structurally changed molecularly to become active when taken orally are, in the end, 17aa's - it is that molecular change that makes them hepatically toxic - so yes if it is a 17aa it is harsh on your liver - that goes for things outside of juice as well - does that answer your question or did I confuse you more?
11-14-2001, 01:42 PM #3
Gee this board moves fast .... I had to look for mee post ...
Yeh to some degree Mike ... So whatever agent , this molecular change to AA-17 is what makes it more toxic than if the compound was left alone to travel thru unchanged ?
11-14-2001, 02:31 PM #4Mike Guest
EXACTLY - it is the process of molecularly changing a compound to become active orally that makes it a 17aa and thus heptically toxic
11-14-2001, 03:10 PM #5Ranger Guest
Quite simply put...Most injectables make one pass through the liver...17AA's make several passes thus becoming harsh on the liver....
Hope this answers in a round about way....
11-14-2001, 04:47 PM #6Mike Guest
Ranger is right - I guess probably easier to understand too
here's a little background:
Naturally-occuring anabolic steroids are synthesised in the testis, ovary and adrenal gland from cholesterol via pregnenolone. Synthetic anabolic steroids are based on the principal male hormone testosterone , modified in one of three ways:
alkylation of the 17-carbon
esterification of the 17-OH group
modification of the steroid nucleus
Oral steroids being examples of the first of those three routes. The substitution of that 17-alpha carbon is what makes these steroids toxic to the liver. This makes these steroids pass through the liver multiple times. As Ranger said.
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