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  1. #1
    Iron horse's Avatar
    Iron horse is offline Anabolic Member
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    anyone with IGF-1r3 experience please post

    please post if you have any experience with this, want to hear the good/bad reviews.

  2. #2
    painintheazz's Avatar
    painintheazz is offline Anabolic Member
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    Bump.

    Pain

  3. #3
    PERSIANBOLIC's Avatar
    PERSIANBOLIC is offline Junior Member
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    I havenít done that one but I did do IGF Long R-3, and I didnít think much of it. But then again I was trying it by it self and not mixing it with GH and slin.

  4. #4
    Iron horse's Avatar
    Iron horse is offline Anabolic Member
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    what were your dosages?

  5. #5
    Iron horse's Avatar
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    bump

  6. #6
    Ghoust is offline New Member
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    IGF-1
    "To understand how IGF-1 works you have to understand how muscles grow. The ability of muscle tissue to constantly regenerate in response to activity makes it unique. Itís ability to respond to physical/mechanical stimuli depends greatly on what are called satellite cells. Satellite cells are muscle precursor cells. You might think of them as "pro-muscle" cells. They are cells that reside on and around muscle cells. These cells sit dormant until called upon by growth factors such as IGF-1. Once this happens these cells divide and genetically change into cells that have nuclei identical to those of muscle cells. These new satellite cells with muscle nuclei are critical if not mandatory to muscle growth.

    Without the ability to increase the number of nuclei, a muscle cell will not grow larger and its ability to repair itself is limited. The explanation for this is quite simple. The nucleus of the cell is where all of the blue prints for new muscle come from. The larger the muscle, the more nuclei you need to maintain it. In fact there is a "nuclear to volume" ratio that cannot be overridden. Whenever a muscle grows in response to functional overload there is a positive correlation between the increase in the number of myonuclei and the increase in fiber cross sectional area (CSA). When satellite cells are prohibited from donating new nuclei, overloaded muscle will not grow (Rosenblatt,1992 & 1994; Phelan,1997). So you see, one important key to unnatural muscle growth is the activation of satellite cells by growth factors such as IGF-1.

    IGF-1 stimulates both proliferation (an increase in cell number) and differentiation (a conversion to muscle specific nuclei) in an autocrine-paracrine manner, although it induces differentiation to a much greater degree. This is in agreement with the Dual Effector theory. In fact, you can inject a muscle with IGF-1 and it will grow! "

  7. #7
    Iron horse's Avatar
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    cool

  8. #8
    Ghoust is offline New Member
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    here is an interesting read on the product.
    http://www.anabolicscience.com/forum...threadid=10122

    posted by DrJMW

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