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  1. #1
    Flash is offline New Member
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    Are winny and tren synergistic or is that just myth?

    I get some progesterogenic sides from tren (acne, depression, swollen nips) and have read conflicting theories on Winstrols ability to act at the progesterone receptor, but not cause transcription.

    I loved the way tren got my strength up and improved my recovery, but the depression and acne sucked. In my next cycle I want to run test/tren/winny, but I'd like to get an expert opinion the likelyhood of winny cancelling out the negative sides i get from tren.

    Is the acne from tren because of its strong androgen affinity or because Im getting a lot of progesterone conversion?

    Any opinions?

  2. #2
    XBiker's Avatar
    XBiker is offline Retired Vet
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    Re: Are winny and tren synergistic or is that just myth?

    Originally posted by Flash
    I get some progesterogenic sides from tren (acne, depression, swollen nips) and have read conflicting theories on Winstrols ability to act at the progesterone receptor, but not cause transcription.

    I loved the way tren got my strength up and improved my recovery, but the depression and acne sucked. In my next cycle I want to run test/tren/winny, but I'd like to get an expert opinion the likelyhood of winny cancelling out the negative sides i get from tren.

    Is the acne from tren because of its strong androgen affinity or because Im getting a lot of progesterone conversion?

    Any opinions?
    It could be either. Your body may be reacting in a negative manner to the tren and that is why you are getting the sides.

    I would definitely run Winny with it, 50 MG / EOD at the minimum. I am personally runnning 75 MG / ED with mine.

  3. #3
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    Winstrol and Tren probably have some synergy, yes. One is a 19-nor steroid with strong receptor binding (Tren), and one is a DHT steroid with weak receptor binding (winstrol). Thus, since they both act on your body in vastly different ways, they probably produce a synergistic effect (1+1=3) rather than simply an additive one (1+1=2).

  4. #4
    odrorir's Avatar
    odrorir is offline Associate Member
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    Use HCG with a suppressive compound like Tren ...
    Should really help you out.

    Winny's affinity for the progesterone receptor is not known, so it may be too weak to do much... Or the other way around.

    Quote Originally Posted by Flash
    I get some progesterogenic sides from tren (acne, depression, swollen nips) and have read conflicting theories on Winstrols ability to act at the progesterone receptor, but not cause transcription.

    I loved the way tren got my strength up and improved my recovery, but the depression and acne sucked. In my next cycle I want to run test/tren/winny, but I'd like to get an expert opinion the likelyhood of winny cancelling out the negative sides i get from tren.

    Is the acne from tren because of its strong androgen affinity or because Im getting a lot of progesterone conversion?

    Any opinions?

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