Explanation of HPTA / Endocrine System & How Steroids Affect You

**oxfordbeta** · 07-12-2014, 12:03 AM

Always have very educational posts, thanks. Just one question about HCG , Is it used to basically keep your "system" from ever completely shutting down? Thanks again.

**davesah1** · 07-12-2014, 12:06 AM

random question, what about corticosteroids? I was prescribed these multiple times as a teen.

**austinite** · 07-12-2014, 05:20 AM

Originally Posted by oxfordbeta

Always have very educational posts, thanks. Just one question about HCG, Is it used to basically keep your "system" from ever completely shutting down? Thanks again.

No. The following thread will answer all your questions with respect to hCG :

HCG: Why you should use it on-cycle only & how to prepare your hCG for injections

**austinite** · 07-12-2014, 05:21 AM

Originally Posted by davesah1

random question, what about corticosteroids? I was prescribed these multiple times as a teen.

What's the question, dave?

**jsam** · 07-12-2014, 07:32 AM

Austinite would like your opinion on my situation I posted about above.

Thanks

**davesah1** · 07-12-2014, 06:29 PM

Originally Posted by austinite

What's the question, dave?

Do they effect the HPTA or pituitary, my knowledge on them is very limited. All I recall is they cause the adrenal glands to secrete more and have anti inflammatory properties. But I was always weened off them and was never allowed to take them for more than 2 weeks. So I was just curious.

**austinite** · 07-12-2014, 08:13 PM

Originally Posted by davesah1

Do they effect the HPTA or pituitary, my knowledge on them is very limited. All I recall is they cause the adrenal glands to secrete more and have anti inflammatory properties. But I was always weened off them and was never allowed to take them for more than 2 weeks. So I was just curious.

Corticosteroids are mild on HPTA, but they are suppressive to a degree. I recall a study stating that testosterone , LH and FSH were all reduced by around 20%. But HPAA (hypohalmaic, pituitary adrenal axis) is heavily suppressed.

I think the main concern is with longterm use. Impact can be permanent and in some cases, can cause hypogonadism. But I think it's fair to say that hypogonadism would be rare.

**Back In Black** · 08-16-2014, 01:57 AM

Bump, for all you kids who think you are mature enough.

**EquilibriumZ** · 08-16-2014, 01:05 PM

Originally Posted by austinite

Corticosteroids are mild on HPTA, but they are suppressive to a degree. I recall a study stating that testosterone , LH and FSH were all reduced by around 20%. But HPAA (hypohalmaic, pituitary adrenal axis) is heavily suppressed.

I think the main concern is with longterm use. Impact can be permanent and in some cases, can cause hypogonadism. But I think it's fair to say that hypogonadism would be rare.

Fak, i was injected twice in the past year and i m 21..
Goodbye Sweet HPTA

**jazzy91** · 08-23-2014, 11:41 PM

great info thanks for taking the time, looking to educate myself so i can cycle safely!

**poppz** · 08-24-2014, 12:28 AM

Very good info for me. Thnx

**ronoznofing** · 09-18-2014, 11:26 AM

I read through the comments and didnt find an answer to this... and there is a lot of conflicting info on the forum about this so I wanted to ask you, Austinite, my new favorite body chemistry teacher. How would you calculate Clomid and Nolva dosing for PCT?

I've read almost all of your articles on here. Thanks for sharing your knowledge.

**kelkel** · 09-18-2014, 12:13 PM

Originally Posted by EquilibriumZ

Fak, i was injected twice in the past year and i m 21..
Goodbye Sweet HPTA

No worries with two injections. Austin's response was spot on, as usual. This will seal the deal.

Testosterone levels during systemic and inhaled c... [Respir Med. 1994] - PubMed - NCBI

**jdc91gt** · 09-18-2014, 12:19 PM

Thanks! Well done.

**Mr.BB** · 09-18-2014, 02:45 PM

Originally Posted by ronoznofing

I read through the comments and didnt find an answer to this... and there is a lot of conflicting info on the forum about this so I wanted to ask you, Austinite, my new favorite body chemistry teacher. How would you calculate Clomid and Nolva dosing for PCT?

I've read almost all of your articles on here. Thanks for sharing your knowledge.

Your answer is here: My First Cycle: Planning and Executing a Successful First Cycle

**poizonn** · 11-16-2014, 06:32 AM

I can't thank you enough for all the time and effort you spend on helping us, thank you!

**austinite** · 11-16-2014, 09:57 AM

Thank you for reading.

**BigRig916** · 11-16-2014, 04:30 PM

This was a great read for a new member to the forum such as myself. Hope all of us newbies are reading this type of important information. Thanks for sharing.

**Bobby B** · 12-15-2014, 06:23 AM

Wow, what an informative post. Definitely learned something new. Thanks.

**austinite** · 01-16-2015, 06:06 AM

New year bump to welcome all the new members. Understand your HPTA!

**kelkel** · 01-16-2015, 07:36 AM

Originally Posted by austinite

New year bump to welcome all the new members. Understand your HPTA!

I'd give you a new years bump looking all hot in your avi.

**austinite** · 01-16-2015, 07:37 AM

Originally Posted by kelkel

I'd give you a new years bump looking all hot in your avi.

hey now!

**NACH3** · 01-16-2015, 08:00 AM

Perfect!

**ahmadyar** · 01-16-2015, 08:11 AM

Thank you so much ! One question I have sometimes heard that some men have received infertility I mean that men can not get a woman pregnant ?? Will This Happen when the human HPTA is shut downed?? IF yes ! So there is one way to fix it !?

**austinite** · 01-16-2015, 08:23 AM

Originally Posted by ahmadyar

Thank you so much ! One question I have sometimes heard that some men have received infertility I mean that men can not get a woman pregnant ?? Will This Happen when the human HPTA is shut downed?? IF yes ! So there is one way to fix it !?

as stated in the article, either way is possible. You can most certainly get a female pregnant.

**NACH3** · 01-16-2015, 08:27 AM

double post...

**ahmadyar** · 01-16-2015, 08:57 AM

Originally Posted by austinite

as stated in the article, either way is possible. You can most certainly get a female pregnant.

ohh Nice to hear that! I am Too young now But I'm trying to get information and I want to try a Anabolic Steroid when im older!

As you've said Proper cycling and pct will better for chances of recovery. How i can know what is the right Cycle and Pct For me ? because I do not want to make any mistakes

**austinite** · 01-16-2015, 09:35 AM

Originally Posted by ahmadyar

ohh Nice to hear that! I am Too young now But I'm trying to get information and I want to try a Anabolic Steroid when im older! As you've said Proper cycling and pct will better for chances of recovery. How i can know what is the right Cycle and Pct For me ? because I do not want to make any mistakes

best to read the "my first cycle" sticky thread. It has all your answers.

**Tactmed** · 02-21-2015, 02:18 PM

There is an article written on this site titled "How to come off steroids ". In that article it states that for PCT to only choose one SERM. Choose either Clomid or Nolvadex , and that both taken together is not needed. Can you clarify this please.

**austinite** · 02-21-2015, 10:27 PM

Originally Posted by Tactmed

There is an article written on this site titled "How to come off steroids". In that article it states that for PCT to only choose one SERM. Choose either Clomid or Nolvadex, and that both taken together is not needed. Can you clarify this please.

Sure. Here you go.

**razman** · 03-01-2015, 05:15 PM

Originally Posted by austinite

Introduction

This competitiveness will ONLY happen with the presence of BOTH compounds and will inevitably resolve the issue of excess estrogen in the Hypothalamus. This will trigger both LH and FSH to crank UP, as the high estrogen in this cluster is suppressive. You need the synergy so don't take chances.

Can someone please elaborate what is meant by this? What is this excess estrogen in the hypothalamus?

**austinite** · 03-01-2015, 05:21 PM

Estrogen in your hypothalamus will suppress gnrh. Therefore; your natural LH/FSH will not be produced. Removing the excess estrogen will bring production back to life, thus; recovery.

**blakegains** · 03-06-2015, 10:01 PM

Awesome, thanks!

**MSphysique** · 03-30-2016, 08:26 AM

Great post thank you!

**PrimoCyp25** · 11-09-2018, 12:26 PM

I've learned so much from you, I was brought up on old school gearing, with all the wrong ideas we use to have about properly doing things to minimize negative effects of our actions, after 12 years my 1st cycle and running just test, I'm getting great results, with 250 hcg and Arimidex , have Nolva and clomid waiting, looking for not crashing like I use to, Thanks for sharing.