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Thread: Is heart hypertrophy reversible? -Serious question-

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    matri.x's Avatar
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    Is heart hypertrophy reversible? -Serious question-

    With many autopsy reports coming (Dalas, Rich...) all had an Enlarged hearts and Im sure some of us have heart hypertrophy already.

    Is it reversible? Our muscles shrink back to normal size after we stop using steroids right? So why don't the heart just get back to normal size too?

    any links? threads? Ideas?

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    my opinion, NO its not reversible . Cardiac muscle is much different then skeletal muscle. the enlargement of cardiac muscle is the enlargement of the actual tissue , where skeletal muscle can be filled with glycogen and water and increase its size significantly (but take away the water and glycogen and it shrinks back down) , this is why you see former pro bodybuilders that used to weigh 300 pounds now only weighing 200 pounds

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    also keep in mind that it was NOT enlarged heart that killed either of those guys . you can live a long life with an enlarged heart, plenty of athletes (ex football , basketball players etc) have enlarged hearts.

    Dallas' heart had a blockage at the left ventricle , this is a genetic misfortune that lead to his heart attack/heart failure.
    Rich's heart was enlarged, but had no other issues (small amount of plaque build up which is normal for someone 50 years old). His heart went into arrhythmia and stopped beating more then likely from a drug induced cardiac event.

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    https://www.ncbi.nlm.nih.gov/pubmed/28512310

    Google "pubmed LVH reversable" to read more.
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    It’s reversible but only in certain conditions. LVH when induced as a normal adaptation to an athletic lifestyle will reduce with detraining. Pathological or congenitally induced LVH doesn’t seem to reduce in any meaningful fashion.
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    Quote Originally Posted by MuscleScience View Post
    It’s reversible but only in certain conditions. LVH when induced as a normal adaptation to an athletic lifestyle will reduce with detraining. Pathological or congenitally induced LVH doesn’t seem to reduce in any meaningful fashion.
    Pathologically it can, but it required a certain beta blocker (carvedilol) in conjunction with a biventricular pacemaker to remodel the heart in my case.
    Congenitally induced, I've heard of limited success with left ventricle sleeve gastrectomy, but I don't think it is very common yet?
    As far as I know( I'm no expert, lol) if no surgical or medical intervention is done, then it typically stays the same or worsens?

    Edit: Of course, if cardiac output/ejection fraction is somewhere close to normal 40%+, neither of the procedures above are necessary and they seem to write it off as an athletic heart/lvh.
    Last edited by almostgone; 12-03-2017 at 02:59 PM.
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    Quote Originally Posted by almostgone View Post
    [

    Pathologically it can, but it required a certain beta blocker (carvedilol) in conjunction with a biventricular pacemaker to remodel the heart in my case.
    Congenitally induced, I've heard of limited success with left ventricle sleeve gastrectomy, but I don't think it is very common yet?
    As far as I know( I'm no expert, lol) if no surgical or medical intervention is done, then it typically stays the same or worsens?

    Edit: Of course, if cardiac output/ejection fraction is somewhere close to normal 40%+, neither of the procedures above are necessary and they seem to write it off as an athletic heart/lvh.
    I should have qualified that as saying without medical or surgical intervention. The remodeling aspect is actually what is important. As long as the heart isn’t irritating or compressing the pericardial sac and function can be somewhat restored to the heart. Reduction in size is not really and end game or issue.

    The stuff I worked on and was privy too was basically all about how you got the heart to remodel in a positive manner. If you could somehow restore flexibility to the heart wall along with blood supply to the functioning part of the heart. The body would remodel the dead or necrotic parts of the heart with connective tissues to help augment the healthy parts.
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    Now that is the really cool stuff. Always amazes me at how the heart can correct some defects on its own. People with blockages that grow new collateral blood vessels as a backup supply to improve bloodflow, function, etc.
    Interesting, waaay over my head in many aspects, but fascinating as hell!
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    Quote Originally Posted by kelkel View Post
    Thanks for the link, that's a very new and promising study. just to be sure, do IGF-1 and HGH the only ones that stimulates FGF23?

    Or all gear do it?

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    I've experienced some health issues over the last year and half which also uncovered some secondary concerns. I've got an enlarged heart LV, Kidneys, Spleen, bladder and prostate. All these have been related to my extensive AAS and GH use over the last 32 years. The main concern of the enlarged organs is the heart and I've asked this exact question regarding is it reversible and I've had two different professional opinions. I've been doing some research myself over the last few weeks on this subject because there seems to be very little when you throw AAS and GH in the mix. My priority at this stage is to reduce my weight which was such a struggle to come to terms with when I've trained all my life to be this freak but health is priority for me over anything.
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    Quote Originally Posted by marcus300 View Post
    I've experienced some health issues over the last year and half which also uncovered some secondary concerns. I've got an enlarged heart LV, Kidneys, Spleen, bladder and prostate. All these have been related to my extensive AAS and GH use over the last 32 years. The main concern of the enlarged organs is the heart and I've asked this exact question regarding is it reversible and I've had two different professional opinions. I've been doing some research myself over the last few weeks on this subject because there seems to be very little when you throw AAS and GH in the mix. My priority at this stage is to reduce my weight which was such a struggle to come to terms with when I've trained all my life to be this freak but health is priority for me over anything.
    Wish you the best there Marcus.

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