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  1. #1
    Unity66 is offline Associate Member
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    Oct 2001

    Your heart and AS.........everyone should read

    this is an interesting abstract.........enjoy the read!!

    taken without permission:

    I used to think that steroids would cause an enlarged heart also....but after doing some research I say it does not.
    Read this article:

    The Positive Effects of Testosterone on the Heart
    by Doug Kalman MS, RD

    Steroids will cause your kidneys to implode, your heart to blow a ventricle, and your liver to squirt out of your arse, fly across the room, and knock the cat off the futon. We read it on the Internet and saw an after school special about it, so it must be true, right?
    Actually, the more you learn about steroids, the more you come to realize that, like all drugs, there's a difference between their intelligent use and outright abuse. In this article, Doug Kalman takes a look at the effects of Testosterone on the heart. What he found may surprise you.

    Over the years we've all heard the repeated mantra that anabolic steroids are bad for the heart. Some physicians will tell you that gear raises your risk of heart disease by lowering your good cholesterol (HDL) and raising your bad cholesterol (LDL). In fact, as some docs will tell you, steroids are known to even induce cardiac hypertrophy (enlargement of the heart). And since you can't flex your heart in an effort to woo women, who'd want that?
    But, as in every story, there's more than one side. In fact, let it be said, the dangers of steroids are overstated and, hold onto your seats, may even be good for the heart. Let's examine some of the scientific studies on the positive effects of Testosterone on the heart.

    What are the cardiovascular effects of steroids ?
    Cardiologists at the Royal Prince Alfred Hospital in Australia recruited both juicing and non-juicing bodybuilders for a study. Each bodybuilder had various aspects of the heart measured (carotid intima-media thickness, arterial reactivity, left ventricular dimensions, etc.). These measurements indicate whether bodybuilding, steroid usage or both affect the function, size, shape and activity of the heart.
    The doctors found some obvious and not so obvious results. Predictably, those bodybuilders who used steroids were physically stronger than those who didn't. What was surprising was that the use of steroids was not found to cause any significant changes or abnormalities of arterial structure or function.
    In essence, when the bodybuilders (both groups) were compared with sedentary controls, any changes in heart function were common to bodybuilders. The take home message from this study is that bodybuilding itself can alter (not impair) arterial structure/function and that steroids do not appear to impair cardiac function. (1)

    Does MRFIT need a T boost?
    A famous cardiac study was published about 10 years ago. It soon became on ongoing study known as the Multiple Risk Factor Intervention Trial (MRFIT). The present study examined changes in Testosterone over 13 years in 66 men aged 41 to 61 years. The researchers determined if changes in total Testosterone are related to cardiovascular disease risk factors.
    The average Testosterone levels at the beginning of the study were 751 ng/dl and decreased by 41 ng/dl. Men who smoked or exhibited Type A behavior were found to have even greater decreases in T levels. The change in Testosterone was also associated with an increase in triglyceride levels and a decrease in the good cholesterol (HDL).
    The authors concluded that decreases in Testosterone levels as observed in men over time are associated with unfavorable heart disease risk. (2) Sounds to me like a good reason to get T support/replacement therapy in the middle age years!
    In a similar study, researchers in Poland examined if Testosterone replacement therapy in aging men positively effected heart disease risk factors. Twenty-two men with low T levels received 200 mg of Testosterone enanthate every other week for one year. Throughout treatment, Testosterone, estradiol, total cholesterol, HDL and LDL were measured.
    The researchers determined that T replacement returned both Testosterone and estradiol levels back to normal and acceptable levels. They also found that T replacement lowered cholesterol and LDL (the bad cholesterol) without altering HDL (the good cholesterol). Furthermore, there was no change in prostate function or size.
    The take home message from this study is that T replacement doesn't appear to raise heart disease risk and it may actually lower your risk. (3) It appears that more physicians should be prescribing low dose Testosterone to middle age and aging men for both libido, muscle tone and for cardiac reasons.

    What about younger men?
    It's been long established that men have a higher risk of heart disease. One of the risk factors implicated is Testosterone. Reportedly, the recreational use of Testosterone can alter lipoprotein levels and, in fact, case reports exist describing bodybuilders who've abused steroids and have experienced heart disease or even sudden death. But the question remains, is the causal association one of truth or just an association?
    To answer this, researchers at the University of North Texas recruited twelve competitive bodybuilders for a comprehensive evaluation of the cardiovascular effects of steroids. Six heavyweight steroid-using bodybuilders were compared with six heavyweight drug-free bodybuilders.
    As expected, the heavy steroid users had lower total cholesterol and HDL levels as compared to the drug-free athletes. What was unexpected was that the steroid users also had significantly lower LDL (the bad cholesterol) and triglyceride levels as compared to the non-steroid users. In addition, the juicers also had lower apolipoprotein B levels (a marker for heart disease risk). Thus, the authors concluded that androgens do not appear to raise the risk of cardiovascular disease. (4) The take home message from this study is that the negative cardiac side effects of steroids are most likely overstated.
    In a little more progressive study, researchers at the Albert Einstein College of Medicine in the Boogie Down Bronx (the BDB to those in the know) examined Testosterone as a possible therapy for cardiovascular disease. (5) The researchers note that T can be given in oral, injectable, pellet and transdermal delivery forms. It's noted that injections of Testosterone (100 to 200 mg every two weeks) in men with low levels of T will decrease total cholesterol and LDL while raising the HDL.
    In fact, Testosterone therapy has been found to have antianginal effects (reduces chest pain). Low levels of Testosterone are also correlated with high blood pressure, specifically high systolic pressure. The researchers determined that returning T levels back to normal and even high-normal levels have positive cardiovascular effects and should be considered as an adjunctive treatment for maintaining muscle mass when someone has congestive heart failure.

    Putting it all together
    Strong research demonstrates that the risks of negative cardiovascular effects of steroids are overstated. In fact, a recent paper published in the Canadian Journal of Applied Physiology questioned the whole risk of using steroids. (6) Joey Antonio, Ph.D. and Chris Street MS, CSCS published strong data showing that the risks of steroid use are largely exaggerated, much like scare tactics used by your parents while you were a kid. Of course, it goes unsaid that abuse of anything will lead to unwanted consequences.
    We know that as we age, circulating Testosterone levels naturally decrease. For most people the Testosterone decrease goes from high-normal to mid to low normal. Data shows that there's an inverse relationship between T levels and blood pressure as well as abdominal obesity (that paunch we see on so many middle age males).
    Testosterone replacement lowers abdominal obesity and restores Testosterone back to normal levels. Restored Testosterone is correlated with better mood, better muscle tone, stronger sex drive, lower cardiovascular disease risks, stronger bones and better memory. It's important to note that while conservative use gives a pronounced positive health benefit, higher doses may not necessarily lead to further health benefits.

    What to do
    If you see your body composition changing (your gut starts looking like your Uncle Lester's), your strength or muscle tone diminishing despite your hard training and good diet, and your sex drive not matching up to TC's columns, have your Testosterone levels checked. The acceptable normal range for Testosterone to physicians is 300 mg/dl to 1100 mg/dl. Yes, that's a pretty wide range.
    In the clinic, we see people with the complaints consistent with "andropause " (a term for male menopause) and/or increased cardiovascular risk having Testosterone levels between 300 mg/dl and 550 mg/dl. Bringing it up to the mid to high-normal level is what gives the health and "youthful" benefits. Traditionally 200 mg/dl of supplemental Testosterone given every one to two weeks improves body composition, lowers total cholesterol and LDL, while raising HDL.
    It appears that supplemental T is a healthier and safer way to go than many of the drugs used to treat poor lipid profiles. The data presented in this article applies for males over 35, not those who are 18. If you think that you can benefit from Testosterone therapy look for physicians who market themselves as "anti-aging" or "longevity physicians" as well as the more progressive endocrinologists or cardiologists.
    Long story short, used intelligently, Testosterone is good medicine!

    About the author: Douglas S. Kalman MS, RD is a Director for Miami Research Associates ( a leading pharmaceutical and nutrition research organization in Miami, Florida. Doug is also a national spokesperson for the American College of Sports Medicine and according to his latest test has high T levels. Doug can be reached at

    1) Sader MA, Griffiths KA, McCredie RJ, et al. Androgenic anabolic steroids and arterial structure and function in male bodybuilders. J Am Coll Cardiol 2001;37(1):224-230.
    2) Zmuda JM, Cauley JA, Kriska A, et al. Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle aged men. A 13 year follow-up of former Multiple Risk Factor Intervention Trial participants. Am J Epidemiol 1997;146(8):609-617.
    3) Zgliczynski S, Ossowski M, Slowinska-Srednicka J, et al. Effect of testosterone replacement therapy on lipids and lipoproteins in hypogonadal and elderly men. Atherosclerosis 1996;121(1):35-43.
    4) Diekerman RD, McConathy WJ, Zachariah NY. Testosterone, sex hormone-binding globulin, lipoproteins and vascular disease risk. J Cardiovasc Risk 1997;4(5-6):363-366.
    5) Shapiro J, Christiana J, Frishman WH. Testosterone and other anabolic steroids as cardiovascular drugs. Am J Ther 1999;6(3):167-174.

  2. #2
    atwa is offline Associate Member
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    Oct 2001
    good read.........thank you bro!!!

  3. #3
    TNT's Avatar
    TNT is offline Retired Moderator
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    Nov 2001
    Mid-Atlantic U.S.

    Cool If A=B and B=C, then A=C, but NOT necessarily D . . .

    I'm glad that Unity66 posted this article, but I think it's important to attribute it to its source, which is Tstosterone magazine. Source information is always important in case one wants to read the original and to indicate any bias or conflict of interest that the publisher may have (like selling supplements, for example).

    Douglas Kalman, the author of the article, has a solid reputation in nutrition research. However, we should keep in mind that he is a registered dietician, not an endocrinologist or cardiologist, thus his conclusions do not hold the same weight as a physician who was actually involved in the study.

    More important, however, is that we not engage in a logical fallacy as far as concluding that all AS are "heart-healthy," and even Kalman is guilty of this in the first paragraph of his own article. He makes a blanket statement about anabolic steroids in general, then goes on to discuss testosterone in specific. What we have is the old adage about comparing apples with moon rocks. Just because the use of testosterone can improve cardiac health does not mean that the same thing applies to winny, deca , D-Bol, EQ, ad infinitum. Therefore, we can not make a blanket statement about AS based solely on a study that involved testosterone supplementation.

    (That doesn't mean that other AS do not have a positive impact on health, nor that they do not have a negative impact on health. It means that, based on the evidence provided, there is not enough information to draw a conclusion one way or the other.)

    Additionally, Kalman's focus, as with most studies involving test, specifically addresses testosterone supplementation (or, as it's known in the medical arena, androgen replacement therapy). And studies universally agree that low testosterone levels can have a negative impact on cardiac health (as well as creatring a higher risk of osteoporosis in men), and that testosterone supplementation can have a positive impact in ameliorating the risk. Kalman does not provide sufficient informtion on the Australian study he referenced to allow a conclusion to be drawn, since he did not elaborate on the specific AS the bodybuilders in the study used. (And, as we all know, everyone tends to do his or her own thing with regard to using AS for BB - there is no one standard cycle for all of us.)

    Finally, we have to be careful when we cite studies supporting androgen replacement therapy as a justification for using AS for BB purposes. Again, apples and moon rocks. Bodybuilders who use test are injecting anywhere from 500 to 1000 (or more) mg. of test per week for a finite number of weeks, usually doing so in combination with other AS, after which the cycle ends. They are also using many types of test which are not normally prescribed for androgen replacement. (The standard for androgen replacement therapy is injectable enanthate or cyp, as well as alternative delivery methods such as patches or gel; only BB's use sust, prop, etc.) On the other hand, patients who inject test for the purpose of androgen replacement generally use, on avverage, 200 mg. every two weeks, with a maximum recommended dosage of 800 mg. per month in divided doses; and they use it on a permanent, ongoing basis, not as part of a finite cycle.

    So what does all this mean? In light of Kalman's reputation and credentials (notwithstanding that he is not in a relevant specialty), his article is interesting reading. But we should not draw conclusions that are not there.

    Thus ends today's lesson in critical thinking.

  4. #4
    G Child's Avatar
    G Child is offline Anabolic Member
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    Nov 2001
    Some kind of padded room...wearing some kinda white jacket...can't!
    Now why can't critical thinking in school be so interesting? Hey TNT, you almost sound as if you've been through Law School!

  5. #5
    ittybittymass's Avatar
    ittybittymass is offline New Member
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    Jul 2003
    hey i just found this by accident. i just thought id say that my mom is an ultrasound tech, she was trying to do an ultrasound on a guy in his young 20s who was obviously juicing, his heart was so enlarged that she couldnt even see anything!

  6. #6
    BUYLONGTERM's Avatar
    BUYLONGTERM is offline Anabolic Member
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    Feb 2003
    Quote Originally Posted by ittybittymass
    hey i just found this by accident. i just thought id say that my mom is an ultrasound tech, she was trying to do an ultrasound on a guy in his young 20s who was obviously juicing, his heart was so enlarged that she couldnt even see anything!
    Bro, no flame but seriously, who knows if it has to do with AS. Your mom as a tech, cant make that determination. Lets just say it does..We don't know how much the guy is taking/or took. We don't know his medical backround. We know NOTHING about him. Trust me, it only takes a few idiots doing shit, to tarnish an image.

  7. #7
    zmatalucci's Avatar
    zmatalucci is offline Associate Member
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    Dec 2002
    good read,,,thanks for the post!

  8. #8
    ittybittymass's Avatar
    ittybittymass is offline New Member
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    Jul 2003
    Bro, if you dont believe large amounts of AS will enlarge your heart, surely you believe large amounts of GH will. dont be a dickhead

  9. #9
    FRANK WHITE's Avatar
    FRANK WHITE is offline Senior Member
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    Nov 2001
    On a beach in California
    Great read bro. Now I don't feel so bad about my long test cycles.

  10. #10
    Terinox's Avatar
    Terinox is offline The One & Only
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    Nov 2001
    Damn that was posted in 2001.

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