Anabolics
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  1. #1
    aljordan45's Avatar
    aljordan45 is offline New Member
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    Question Anavar ? Need Help!!!!!!!!

    Hey everyone, I posted about a week ago about a Anavar and Winny cycle and really didn't get the help I needed! I got a lot of people telling me to take Test and Fina, that really isn't the route I wanted to head down right now! I guess I am too chicken being totally new to a steroid cycle! So my main ? is, am I wasting my time taking ANAVAR and maybe Winny to get some good strength gains and maybe a lil size with MINIMAL SIDE EFFECTS? I posted my pic so you guys can see how I look, I ain't a Novice at lifting by no means! I just wanna break through that wall I hit naturally and keep moving foward! Thanks a lot everyone and hope I can get some good responses!
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  2. #2
    LAWNSAVER's Avatar
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    How much Var??

    How Long?

    Winny can cause big problems with your joints without an androgen that causes water retention.

    Anavar can be very productive, especially with creatine.

  3. #3
    aljordan45's Avatar
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    Quote Originally Posted by LAWNSAVER
    How much Var??

    How Long?

    Winny can cause big problems with your joints without an androgen that causes water retention.

    Anavar can be very productive, especially with creatine.

    I ain't really sure how much to take right yet, I am trying to get some responses on what I should do overall! Any ideas let me know!

  4. #4
    JohnnyB's Avatar
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    Here's a couple of studies that might help.

    Short-term oxandrolone administration stimulates net muscle protein synthesis in young men.

    Sheffield-Moore M, Urban RJ, Wolf SE, Jiang J, Catlin DH, Herndon DN, Wolfe RR, Ferrando AA.

    Department of Surgery, University of Texas Medical Branch, and Shriners Burn Hospital for Children, Galveston 77550, USA. melmoore@utmb.edu

    Short term administration of testosterone stimulates net protein synthesis in healthy men. We investigated whether oxandrolone [Oxandrin (OX)], a synthetic analog of testosterone, would improve net muscle protein synthesis and transport of amino acids across the leg. Six healthy men [22+/-1 (+/-SE) yr] were studied in the postabsorptive state before and after 5 days of oral OX (15 mg/day). Muscle protein synthesis and breakdown were determined by a three-compartment model using stable isotopic data obtained from femoral arterio-venous sampling and muscle biopsy. The precursor-product method was used to determine muscle protein fractional synthetic rates. Fractional breakdown rates were also directly calculated. Total messenger ribonucleic acid (mRNA) concentrations of skeletal muscle insulin -like growth factor I and androgen receptor (AR) were determined using RT-PCR. Model-derived muscle protein synthesis increased from 53.5+/-3 to 68.3+/-5 (mean+/-SE) nmol/min.100 mL/leg (P < 0.05), whereas protein breakdown was unchanged. Inward transport of amino acids remained unchanged with OX, whereas outward transport decreased (P < 0.05). The fractional synthetic rate increased 44% (P < 0.05) after OX administration, with no change in fractional breakdown rate. Therefore, the net balance between synthesis and breakdown became more positive with both methodologies (P < 0.05) and was not different from zero. Further, RT-PCR showed that OX administration significantly increased mRNA concentrations of skeletal muscle AR without changing insulin-like growth factor I mRNA concentrations. We conclude that short term OX administration stimulated an increase in skeletal muscle protein synthesis and improved intracellular reutilization of amino acids. The mechanism for this stimulation may be related to an OX-induced increase in AR expression in skeletal muscle.

    JohnnyB

  5. #5
    JohnnyB's Avatar
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    Anavar at 15mg with high protien diet.

    Combined effects of hyperaminoacidemia and oxandrolone on skeletal muscle protein synthesis.

    Sheffield-Moore M, Wolfe RR, Gore DC, Wolf SE, Ferrer DM, Ferrando AA.

    Department of Surgery, University of Texas Medical Branch, Galveston 77550, USA. melmoore@utmb.edu

    We investigated whether the normal anabolic effects of acute hyperaminoacidemia were maintained after 5 days of oxandrolone (Oxandrin, Ox)-induced anabolism. Five healthy men [22 +/- 3 (SD) yr] were studied before and after 5 days of oral Ox (15 mg/day). In each study, a 5-h basal period was followed by a 3-h primed-continuous infusion of a commercial amino acid mixture (10% Travasol). Stable isotopic data from blood and muscle sampling were analyzed using a three-compartment model to calculate muscle protein synthesis and breakdown. Model-derived muscle protein synthesis increased after amino acid infusion in both the control [basal control (BC) vs. control + amino acids (C+AA); P < 0.001] and Ox study [basal Ox (BOx) vs. Ox + amino acids (Ox+AA); P < 0.01], whereas protein breakdown was unchanged. Fractional synthetic rates of muscle protein increased 94% (BC vs. C+AA; P = 0.01) and 53% (BOx vs. Ox+AA; P < 0.01), respectively. We conclude that the normal anabolic effects of acute hyperaminoacidemia are maintained in skeletal muscle undergoing oxandrolone-induced anabolism.

    JohnnyB

  6. #6
    Da Bull's Avatar
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    Nice post Johnny.


    DB

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