nolvadex question

[pestis]

My understanding is that nolvadex attatches to estrogen receptor sites, thereby blocking those sites from increased levels of estrogens to attach to. What I dont understand is what happens to all that free estrogen after pct is discontinued? Can side effects of AAS use still kick in after nolva use is stopped?

[macrophage69alpha]

estrogen, at least test based estrogen metabolites, are excreted rather quickly.

dbol estrogenic metabolites hand around for a while (how long has not been thoroughly tested)- though likely not more than 3-4 days.


nolva has a half life of 7-10 days, apprx 14 days with extended use (3-4wks).

nolva is an estrogen , it is a mixed agonist/antagonist of the receptor (SERM).

many of the mood issues that occur after cessation of PCT are likely due to high blood levels of the SERM used (clomid has a half life of 5 days, which also extends with use)

[pestis]

estrogen, at least test based estrogen metabolites, are excreted rather quickly.

dbol estrogenic metabolites hand around for a while (how long has not been thoroughly tested)- though likely not more than 3-4 days.


nolva has a half life of 7-10 days, apprx 14 days with extended use (3-4wks).

nolva is an estrogen , it is a mixed agonist/antagonist of the receptor (SERM).

many of the mood issues that occur after cessation of PCT are likely due to high blood levels of the SERM used (clomid has a half life of 5 days, which also extends with use)

Excellent, thanks for the clarity.
hailz,
Pestis

[macrophage69alpha]

as a note- this means that nolva, after the last tab, will have effects for up to a month

also for those that use letro
Tamoxifen reduced the plasma concentration of letrozole by 37% when these drugs were co-administered.

nolva should be used with caution in conjunction with oral steroids as they are both metabolized by cyp3a4. nolva does alter liver test results and may have negative impact on liver function.

[powerlifter]

macro thanks for the info on Nolva and orals