TRT Problems

**timovie** · 04-28-2010, 05:08 PM

I have a history of moderate to severe depression for the last 10 years or so ( i am now 39). I also have had many of the symptoms of low T throughout my adult life such as low energy levels, obesity, low sex drive etc etc. During my latest bout of depression, my GP did a testosterone level check and found my levels to be 4.9 then 3.2 on a second test. I have been diagnosed with hypogonadotropic hypogonadism and about 5-6 weeks ago I started on TRT, using 1 x 5g sachet of Testogel (Androgel ) per day. My initial response was dramatic, my energy levels went through the roof, and I just felt generally great. Unfortunately at the end of that first week, I was asked to take a week off work as they were concerned that I may become physically violent ( I think this was an over reaction on their part, however I do admit I was a bit agressive and confrontational, where I am normally very mild, to the point of being timid). I took a week off and felt better than I have ever felt during my adult life. I was just loving being alive, and finding enjoyment everywhere. I also had great energy levels. This response seemed to fade over the following three weeks or so and when I went to see my endocrinologist, sure enough my T level was higher at 7.2 but still not in the normal range ( lower limit of 8 I believe). I was put on two sachets of testogel per day, and ever since ( about two weeks) I have not experienced any of the great mood or energy levels, in fact I feel really rubbish. I am also having terrible mood swings, ranging from feeling quite seriously depressed one hour to being very angry/confrontational then next hour.

I am starting to think that I have only two options. 1. I can stop the TRT and be depressed but mild mannered or 2. I can carry on and feel generally less depressed, but angry and not very nice to be around ( i am already losing friends).

Can anyone offer any advice ? Do you think I am converting the T to estrogen? I believe this can happen. Would this cause the mood swings i am experiencing? Do I just need to give it more time for things to stabilise ? ( I think people at work are beginning to lose patience with me ) or do I need to try a different delivery method ( I have read that injections/implants are even more likely to give me mood swings).

Any advice would be VERY gratefuly received.

**cjw2021** · 07-05-2010, 06:58 PM

I'd recommend trying 100mg or ml? test cypionate injected twice per week. I tried 200 once per week and I witnessed the same wildness you mentioned.

**n00bs** · 07-05-2010, 07:11 PM

We cant tell anything without TEst results.

I will tame a stab and say you have hypothyroidism people with hypo thyroid do not absorb gel at all as the skin becomes too think. Where are you located?

When I am at a computer and not on phone I will post as much info that i can for you. There is hope my friend so do not worry yourself

I'm guessing you are in Australia please add my men [email protected] so I can give you the details of a professional in this matter.. As your current health care professionals have displayed their lack of knowledge with their continual failed treatment without looking at why.

Do you know your e2?
Shbg
Other tests?

Havethey even tested these? If not run!

**Vettester** · 07-05-2010, 09:06 PM

Like nOObs mentioned, we can't offer too much at this point without some real lab work results. I suggest running a complete hormone panel along with lipids, CBC w/diff, Comp metabolic, thyroid, & PSA, and anything else you can get from DHEA to B12.

It doesn't sound like your doctor has really done much for you. I can tell you from my own experience with AndroGel that I started to experience some unstable results after 5 or 6 months of starting it. I have also read a lot of similar stories from other members that claim the same thing with AndroGel.

No problems what so ever with the injections. It takes a little time to get it dialed-in and optimized, but that's where BW comes in, and hopefully a decent doctor.

**n00bs** · 07-05-2010, 09:11 PM

Originally Posted by vetteman08

Like nOObs mentioned, we can't offer too much at this point without some real lab work results. I suggest running a complete hormone panel along with lipids, CBC w/diff, Comp metabolic, thyroid, & PSA, and anything else you can get from DHEA to B12.

It doesn't sound like your doctor has really done much for you. I can tell you from my own experience with AndroGel that I started to experience some unstable results after 5 or 6 months of starting it. I have also read a lot of similar stories from other members that claim the same thing with AndroGel.

No problems what so ever with the injections. It takes a little time to get it dialed-in and optimized, but that's where BW comes in, and hopefully a decent doctor.

Correct it depends on YOU,

Some people respond to gel (those with low DHT) some respond betetr to dao;y shots (thyroid problems) some respond better to 1 10 week shot...

It needs to be designed for you and your problems... 10g of andro gel is alot of androgel.. A compounding cream would be better if u needed that much through gel. The higher the area of applicaiton the higher the exposure to aromatase and DHT enzymes that will quickly convert your testosterone ...

Testogel is an australian product so if you are here i can reccomend good dr's for you who will investigate properly.