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  1. #1
    dogfight's Avatar
    dogfight is offline Associate Member
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    what can supress igf-1 during pct (letro)

    do you know if letro will supress your igf-1 levels? of any other anti -estrogens can any thing elese?

  2. #2
    JohnnyB's Avatar
    JohnnyB is offline AR-Hall of Famer / Retired
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    Yes it will as with all drugs that are made for breat cancer

    JohnnyB

  3. #3
    Slic4788 is offline Associate Member
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    Not letro but nolva, yes.

  4. #4
    HumanPerfection1 is offline Associate Member
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    nolva deff

  5. #5
    rodge's Avatar
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    letro and aromasin are actually raising igf-1 levels.

    -rodge

  6. #6
    dogfight's Avatar
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    ok so thats the good thing about it but i dont understand if letro is a anti-aromatise why is there a rebound affect? an if i take Ldex to fight the rebound will that lower my igf-1 or just not affect it??
    thanx all!!

  7. #7
    reveremuscle's Avatar
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    Going to start IGF tuesday, last dose of 50mg clomid was friday, should I be all set?

  8. #8
    Slic4788 is offline Associate Member
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    Quote Originally Posted by dogfight
    ok so thats the good thing about it but i dont understand if letro is a anti-aromatise why is there a rebound affect? an if i take Ldex to fight the rebound will that lower my igf-1 or just not affect it??
    thanx all!!
    taper off the letro slowly to avoid the rebound effect.

  9. #9
    supersteve Guest
    There's really no consensus either way.
    In one study letro raised igf-1 (older women) and in another (teenage boys) it was lowered slightly.
    Arimidex also shows conflicting results.

    Tamoxifen certainly seems to lower igf-1. But it does this by suppressing your endogenous GH release. So if you're injecting GH this really isn't of any concern.

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