Thread: huIgf1 and IGFBP-3 = ???
01-18-2006, 08:03 PM #1
huIgf1 and IGFBP-3 = ???
Ok maybe I am a bit behind on this one, (but what else is new?)
Apparently the guys at a certain lab are combining huIGF (not lr3) and IGFBP-3.
IGFBP-3 was the binding protien that cause huIGF to have such a short half life, which brought LR3-IGF to be produced.
Now by combining huIGF and IGFBP-3 it s supposed o somehow increase the effectiveness and half life of huIFG well over 12hours. could it be????
Cmon goose, pinnicle I know you smart ass mofo's are reading this chime on in...
01-18-2006, 09:06 PM #2
I'd like to see the reasoning behind that, binding shortens the half life
01-18-2006, 09:11 PM #3
I actually saw it on another board where OL said they would be working on this prodect and have it sometime after the new year
01-18-2006, 09:23 PM #4
OL sells LR3 IGF-1, but what was the reasoning for using it, cause extending the half-life if rhIGF-1 can't be it and if it is, could you cut and paste the reply so I can read it
01-18-2006, 09:38 PM #5
Sorry guys, I havent been over here in a min... Please forgive my slauthfulness...
The new igf would be the igfbp-3, I think you all will love what it provide for you all, thing is its going to be much more then the lr3igf-1, so im trying to figure out if you guys really want to pay for the new stuff?
Originally posted by *************
igfbp-3 is a binding protein which which will extend the half life to 12 hours!!
Longer than that.... Ive been studing and were looking at a 24 hr life spand. So you would have to use less igf-1, and with the igfbp-3
This was in the one thread I'm gonna take a look around and see if I can find something on it. YgPM johnny
01-18-2006, 09:48 PM #6
yea they have just revamped that entire board so I can't find the post I emailed the lab about it so I'll have something for you on it soon.
01-18-2006, 09:50 PM #7
Extend the half life of what? LR3 IGF-1 of rhIGF-1?
01-18-2006, 09:55 PM #8
Im guessing huIGF cause lr3 was designed to basically work around igfbp-3?!?!
I know its so confusing, thats why I want to find out what they're up to.
01-19-2006, 09:06 AM #9Associate Member
- Join Date
- Mar 2004
yeha , u acan do a pub med search on it, this is going to be th enext weapon in the arsenlaof todays medicine.
IGFBP-3 binds to rh-IGF-1 and prolongues its activity and will release it, when it´s needed, or will slow down metabolic rate of IGF, meaning it will be protected from metabolism by the BP.
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