Thread: IGF-1 genetics
02-18-2004, 11:36 AM #1
I have heard that one can use IGF-1 to change their genetics. Now I am wondering if this means that if I have short biceps and I site inject IGF-1 into them that over time I can change the shape of my biceps? Or does it simply mean that you can increase the number of muscle cells in your body with little effect on the overall shape of your muscle.
02-18-2004, 12:07 PM #2
I think it means increase number of cells (hyperplasia)
02-18-2004, 01:23 PM #3
It depends on how localized the expression would be. If you injected something like a plasmid expressing IGF-1 right into the bicep peak, the expression of IGF-1 would be concentrated, but not limited to, the injection site, and the recruitment of satellite cells would mainly occur at that site. I.e. you'd get more growth at that site.
The studies you're alluding to are using viral-mediated delivery, which will give a more diffuse/expansive expression of IGF-1 well beyond the site of injection. Using this method, the growth would be much more uniform.
02-18-2004, 02:11 PM #4
So could IGF be used for a lagging muscle? I have heard that anything it touches grows, so could you in theory use it for site injections? hmmm....
02-18-2004, 08:32 PM #5Originally Posted by Mr. Sparkle
It's thought that GH's effect on muscle growth is the GH binding to GH receptors on muscle and inducing local expression of IGF-1 within the muscles.
02-18-2004, 08:34 PM #6
they pretty much mean if you have bad genetics when it comes to putting on mass this can help you.
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