Lion! 2 low of a dose to see AI properties?

Here is the situtaion. I am currently conducting some research using letrozole. I have been giving my test subjects .5mg of letro EOD for a total of 2mg/wk. I have noticed the subjects have had a great reduction in libido as well as having dry eyes. I was thinking about reducing the dosage of letro to 3x a week at .25mg on Mon .5mg on Thurs and .25mg on Sun for a total of 1mg/wk. Another varible to consider is that the test subjects have also been getting 10mg of tamox ED and will continue to do so along with the new dosing.

---> Here is the question. Do you think this dosage is going to be to low to see any type of AI properties?

I was thinking about switching to liquidex, however I have had great sucess in my experiments with letro in the past, and I come from the thought if it is not broken why fix it. The problem is I have not seen these sides at the .5mg EOD in subjects in previous experiments. So i'm not exactly sure whats going on here.

if your subjects are dry you can lower the dose. don't space it farther out. just lower the dose. Drop the tamox altogether till PCt........Letro is very strong. L-dex doesn't compare ...stay with letro....I switched 1 time and got gyno.. ..