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Thread: question

  1. #1
    jkarcs055 is offline New Member
    Join Date
    Nov 2004
    Posts
    7

    question

    I have slight tissue formation under my nipple. Pretty small prob from a m1t cycle but anyways what should i use to hopefully rid my self of the tissue

  2. #2
    Join Date
    Sep 2004
    Posts
    10,925
    M1t wouldn't cause gyno it doesn't aromatize...you got methyl test mixed with m1t .....if it caused gyno. A few less reputable companys did this. A Kilo of M1t costs $3500- $6500 a kilo of methyl test costs $200. Sorry to hear your having problems letrozole will fix them . It maytake 2-10 week to see a difference do a search on" letrozole reversed gyno "


    J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):27-34. Aromatase overexpression transgenic mice model: cell type specific expression and use of letrozole to abrogate mammary hyperplasia without affecting normal physiology.

    Mandava U, Kirma N, Tekmal RR.

    Department of Gynecology and Obstetrics, Emory University, 4217 Woodruff Memorial Building, 1639 Pierce Drive, Atlanta, GA 30322-4710, USA.

    Our recent studies have shown thatoverexpression of aromatase results in increased tissue estrogenic activity and induction of hyperplastic and dysplastic lesions in female mammary glands and gynecomastia and testicular cancer in male aromatase transgenic mice. Both aromatase mRNA and protein are overexpressed in transgenic mammary glands and its expression is not limited to epithelial cells. However, it is more in epithelial than in stromal cells.Our results also indicate aromatase overexpression-induced changes in mammary glands can be abrogated [destroyed] with very low concentrations of the aromatase inhibitor, letrozole. Low concentration of letrozole had no effect on normal physiology as indicated by no significant change in the circulating levels of estradiol and follicle stimulating hormone as well as no change in estrogen responsive genes such as the progesterone receptor and lactoferrin in the uterine tissue. These observations indicate that the expression of aromatase in both epithelial and stromal cells can influence the complex interactions of biochemical pathways leading to mammary carcinogenesis and that the aromatase inhibitor, letrozole can be used as chemopreventive agents without affecting normal physiology.

  3. #3
    jkarcs055 is offline New Member
    Join Date
    Nov 2004
    Posts
    7
    werd thank you my order is underway

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