So just trawling the net for info and stumbled upon this summary of andarine (SARM s4) check out the last few lines of text.
Andarine (S-4) is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy,[1] using the non-steroidal androgen antagonist bicalutamide as a lead compound.[2] Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.[3] This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.[4] Clinical development of Andarine has been abandoned, given in humans it results in a series specific toxic metabolite [5].
here's a link to the site if you want to check it out yourselves.
http://www.selleckchem.com/products/Andarine.html
Also found info on a more promising sounding SARM called Ostarine and they had this to say about it:
Ostarine (GTx-024, MK-2866), a non-steroidal agent, is selective androgen receptor modulator (SARM) with anabolic activity. This agent is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostate growth, and muscle growth and strength. Mimicking testosterone's action, this agent may increase lean body mass, thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia. Ostarine has demonstrated promising results in Phase I and II clinical trials .
It's on the same site but here's the link anyway
http://www.selleckchem.com/products/...(MK-2866).html
Hope that was all helpful. SMJ
