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#2
11-05-2009, 10:37 PM
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Definitely better to go with GHRP-2 at Minimum !! I will never use IGF.. I find it as useless as creatine, but that's my own opinion..
Some of my friends run CJC/GHRP-2 + hgh... Others like just going the GHRP-2 route.. and others prefer the ghrp-6... I know I will be going with the GHRP-2 about the 2 month mark in on my GH cycle.. and using about 400mcgs per day.. but a GREAT FRIEND TOLD ME THIS INFO... "GHRP-2 at 100mcg - 250mcg. Wait 10 minutes later and dose 1-4iu of the synthetic GH of your choice. This pulse lasts an hour. Give yourself 2 hours off and do it again. This can be done multiple times a day." And trust me, this man is a genius and knows more about Peps and GH and things of that nature then people know about anything really... So go that route and I bet you a million bucks you will NOT BE DISAPPOINTED... Go the IGF route and you might as well just Western union me your money, because it's that much of a waste.. In my own opinion of course.... 
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#3
11-07-2009, 06:45 PM
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[Well first off for Vic's question, once you get up above 4iu of synthetic GH a day I think that the negative feeback will inhibit GH induced release at the pituitary by CJC-1295/GHRP-6. What do we mean by that? GH in circulation can feedback on the Hypothalamus and the Pituitary. Since we don't need the hypothalamus to give us GHRH (because we supply that with the CJC-1295) we are less concerned with THAT particular inhibition. We can still maintain a concern because GHRP-6 acts in part to also induce further release of GHRH from the hypothalamus but for the most part we have in our syringe THE hypothalamic hormone responsible for GH release so when we inject it, it travels directly to the pituitary and exerts it's effect. The problem though is GH inhibition at the pituitary. The somatotrophs (i.e. cells in the pituitary that release GH from internal stores) have many types of receptors on the cell membrane. Among those types is the growth hormone receptor (GHR). So GH in circulation can bind to a receptor on the very cells that secrete it in the first place. When this occurs it invokes certain mechanisms that result in the somatotroph ceasing GH release. There is nothing about our CJC-1295/GHRP-6 protocol that bypasses the negative feedback mechanisms at the pituitary. If a decent amount of synthetic GH is in our system some of it will bind to a receptor on the somatotroph in the pituitary and any subsequent administration of GHRH (in the form of CJC-1295) will be without influence or effect. So if you are at a bodybuilding dose level in your cycle it is wise to not use both CJC-1295 and GH at least in the same 24 hours. How about if you run synthetic GH every other day can CJC-1295 be used in those off days? We can't rely on the studies that spell out inhibition for us because they don't apply to us, because with CJC-1295 we don't need the hypothalamus to get things going...we just need the pituitary to no longer be under the influence of synthetic GH. I believe (as of today 11/1/08) until I see evidence to the contrary that CJC-1295 will have some effect if used on days when synthetic GH is not used. It may prove to be not as potent as it would be if you waited 2-3 days for the GH "hang over" to clear but IMHO it should still be effective.] It does point out 4iu's or above would be needed to inhibit GH induced release at the pituitary by CJC-1295/GHRP-6 so I guess if you were below this amount and you seperated the two you could stack with decent results, but you say to stack the two within a short period of time which is in total contrast of this opinion. What are your thoughts ?
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#5
11-11-2009, 05:41 PM
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Now what to do with my years supply of HGH 
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#6
11-11-2009, 10:09 PM
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Deuce & Scotchguard,
Looks like my response saying combining HGH & GHRP in short succession may have been premature and not neccesarily correct. The first 40 or so pages of Dat's thread IMO supported my original thought, but looks like he has changed gears a bit. Here is what he posted: Although the first 90% of my thread doesn't reflect it ...my current thinking is that both the GHRP/GHRH can be run with synthetic GH at low dose. Experiments so far with 100mcg GHRP-6 + 100mcg GHRH wait 20 minutes and administer 1iu of GH has demonstrated that GH used this way does not hinder a later pulse created with just the GHRP-6/GHRH alone. Current experiments are identical to the above w/ 2iu instead of 1iu. I suspect that will be okay as well. I suspect also that this can be done multiple times a day if one chose, maybe even every 3 hours around the clock. It is the beginning of something I feel could be a beneficial option for bodybuilders & bodysculpters but also an adjunct therapy for the GH deficient (who respond to the GHRH/GHRPs) and also for those that want higher GH levels w/ some of a blend of natural GH. Remember natural GH release is made up of about 10% of a variety known as 20kda. This GH is just as anabolic w/o the ability to interact w/ the prolactin receptor. In some reports natural GH has less of a negative impact on fasted morning blood glucose readings then does the synthetic 22kda form. So for some they may desire a blend. Lucian reported last year that using 2iu of GH per day w/ two 250mcg dosings of GHRP-6 per day and 1mg of CJC-1295 (split into 2 dosings) felt like around 8 to 12iu of GH. See: cjc/ghrp6 So it may be possible to do more by expending less financial resources across the trilogy. Disclaimer - this was posted 4-25-2009 and is on page 48 of 96 pages.
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#7
11-11-2009, 10:13 PM
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