r-ALA and biotin

**Geebee** · 02-06-2005, 07:11 AM

I'm having 100 mgX3 a day r-ALA. How much biotin (vitamin H) should I take ?

**prolangtum** · 02-06-2005, 09:23 AM

1mg 3 x per day.

**nsa** · 02-06-2005, 11:14 AM

As a general rule, use 1 mg of biotin for every 100 mg of r-ala. Or use glucophase, it has both in the same capsule.

**Geebee** · 02-06-2005, 01:56 PM

Thanks a lot

**Angelis** · 02-06-2005, 02:18 PM

y use Biotin with Alpha Lipoic Acid

**prolangtum** · 02-06-2005, 04:04 PM

Taken from an article on Bulnutrition by David Tolson:
http://www.*************.com/?ingredients_id=31
Although clinical deficiency is rare, subclinical biotin deficiency may be quite common. Studies in animals are finding that the optimal amount for health may be well above that needed to just alleviate classical deficiency symptoms [1]. Suboptimal biotin intake or a marginal deficiency may impair leucine metabolism, affect insulin sensitivity, and increase the risk of birth defects [1, 2, 5-6]. It is also important to note that two common supplements, alpha lipoic acid (ALA) and pantothenic acid (vitamin B5), may both compete with biotin. Specifically, ALA administration to rats results in decreased activity of the biotin-dependent carboxylases, presumably due to structural similarity [7].