Thread: Cutting supplements
07-11-2005, 04:29 PM #1
I just finished up a bulk and I didn't do it as clean as I should have and am learning the hard way (packed on a little too much fat). I'm starting a very strick cutting diet now. Ive started taking a ephedra stack but instead of caffeine I'm using green tea extract. I'm doing this because caffeine makes me too hyper, is green tea a good thing to substitute the caffeine in the stack? Each serving has 300mg green tea leaf extract and 150mg polyphenols, how much do I need? Also are there any other supplements worth while for cutting? L-carntine? Thanks guys.
07-11-2005, 05:44 PM #2
get acetyl-l-carnitine far more effective andgreen tea should be fine.
07-11-2005, 05:48 PM #3King of Supplements
Originally Posted by StoneGRMI
- Join Date
- Mar 2004
- east coast
07-11-2005, 05:57 PM #4
Okay cool, I'll up the green tea. As for the L-Carnitine and acetyl L-Carnitine, whats the difference? I only say that because I just picked up some L-Carnitine for real cheap but havent cracked the seals on it yet.
07-11-2005, 09:21 PM #5
Anyone know the difference between L-Carnitine and acetyl L-Carnitine? Just want to know if its worth returning the L-Carnitine I already bought. Thanks!
07-11-2005, 10:21 PM #6
from an article by david tolson on 1 f ast400.com:
"What form is best?
Pharmacologically speaking, there is little difference between supplementing with L-carnitine and supplementing with ALCAR. This is because ALCAR is deacetylated during or immediately after intestinal cell uptake, and then a certain amount of free carnitine is later reacetylated (1, 2). Similarly, it has been shown that supplementation with both L-carnitine and ALCAR increase tissue levels of both substances, and that the intestine creates significant amounts of ALCAR from carnitine (2, 3). "
07-12-2005, 01:21 AM #7VET
Originally Posted by prolangtum
- Join Date
- Nov 2001
these claims are accurate.
Acetyl-l-carnitine sigificantly raises plasma acetyl-l-carnitine levels (see below)
acetyl-l-carnitine has significant effects not seen with carnitine supplementation. (see pubmed)
Ann N Y Acad Sci. 2004 Nov;1033:30-41. Related Articles, Links
Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism.
Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA. email@example.com
In mammals, the carnitine pool consists of nonesterified L-carnitine and many acylcarnitine esters. Of these esters, acetyl-L-carnitine is quantitatively and functionally the most significant. Carnitine homeostasis is maintained by absorption from diet, a modest rate of synthesis, and efficient renal reabsorption. Dietary L-carnitine is absorbed by active and passive transfer across enterocyte membranes. Bioavailability of dietary L-carnitine is 54-87% and is dependent on the amount of L-carnitine in the meal. Absorption of L-carnitine dietary supplements (0.5-6 g) is primarily passive; bioavailability is 14-18% of dose. Unabsorbed L-carnitine is mostly degraded by microorganisms in the large intestine. Circulating L-carnitine is distributed to two kinetically defined compartments: one large and slow-turnover (presumably muscle), and another relatively small and rapid-turnover (presumably liver, kidney, and other tissues). At normal dietary L-carnitine intake, whole-body turnover time in humans is 38-119 h. In vitro experiments suggest that acetyl-L-carnitine is partially hydrolyzed in enterocytes during absorption. In vivo, circulating acetyl-L-carnitine concentration was increased 43% after oral acetyl-L-carnitine supplements of 2 g/day, indicating that acetyl-L-carnitine is absorbed at least partially without hydrolysis. After single-dose intravenous administration (0.5 g), acetyl-L-carnitine is rapidly, but not completely hydrolyzed, and acetyl-L-carnitine and L-carnitine concentrations return to baseline within 12 h. At normal circulating l-carnitine concentrations, renal l-carnitine reabsorption is highly efficient (90-99% of filtered load; clearance, 1-3 mL/min), but displays saturation kinetics. Thus, as circulating L-carnitine concentration increases (as after high-dose intravenous or oral administration of L-carnitine), efficiency of reabsorption decreases and clearance increases, resulting in rapid decline of circulating L-carnitine concentration to baseline. Elimination kinetics for acetyl-L-carnitine are similar to those for L-carnitine. There is evidence for renal tubular secretion of both L-carnitine and acetyl-L-carnitine. Future research should address the correlation of supplement dosage, changes and maintenance of tissue L-carnitine and acetyl-L-carnitine concentrations, and metabolic and functional changes and outcomes.
07-12-2005, 12:59 PM #8King of Supplements
Originally Posted by macrophage69alpha
- Join Date
- Mar 2004
- east coast
07-12-2005, 03:56 PM #9
Thanks a lot guys, helped a lot
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