Hmb ?

[NJTGG]

Is there anyone out there that can explain to me the good and bad qualities of HMB. Is there anyplace that i can get a good deal for this stuff cause it seems like its exspensive everyplace i look, and how much of this stuff should i take each day and for how long?

[KeyMastur]

Yeah, it's expensive. It's basically creatine and something else in it right ?? I think I took that back in the day before I learned about the good ole stuff called juice. Are you looking to add it to a cycle or take it alone ??? I'm sure if you plan on taking it alone there's a cheaper alternative....

[Scorpion]

Save your money. HMB = Horse Manure Bullcrap. I can't believe how expensive it is and how Bill Phillips of EAS once said that taken over a year the results and gains are better than that of some steroids .
Yeah okay, Bill.

[jbrand]

Originally posted by Scorpion
Save your money. HMB = Horse Manure Bullcrap. I can't believe how expensive it is and how Bill Phillips of EAS once said that taken over a year the results and gains are better than that of some steroids .
Yeah okay, Bill.

But Bill told me "it feels like deca !".

I'll never forget that article

[dr_ma]

I've taken it and I got gains that I would say were equivalant to a mild cycle of steroids . However, I took more than the required dose and I took it for about 3 monthes. I do think it is a good supplement but it take a while before it really starts to work and you need a little more than the suggested dosage. I was taking about 1.5 g 3x daily. I also was taking creatine which I think is also a must while taking this.

[RP7]

The new issue of Men's Health (I know this isn't the best source) said HMB and creatine were essentially the only supplements that work. I think I might give'r a shot, once I get some cash that is...

[DBarcelo]

HMB is kinda expensive, but not really. Not like it's $50 a bottle.

It's not something that's meant to help build muscle, it's supposed to help keep you from losing muscle. You also have to take it three times per day. At least 3 grams per day.

I don't know of any negative effects.

And, no, there isn't any creatine in it. It's basically a type of calcium called B-Hydroxy-B-Methylbutyrate-Monohydrate.

[sinista63]

It's basically a type of calcium called B-Hydroxy-B-Methylbutyrate-Monohydrate.

Its not a type of calcium. Its a derivative of leucine, an amino acid, and alpha-ketoisocaproate, the keto acid of leucine. Some of the latest research involving the use of HMB for strength training has been less than impressive. The way its supposed to work is by reducing protein degradation. It may also increase recovery of damaged muscle cells. I haven't had a chance to actually read through some of these trials so I don't know if they just weren't designed properly. The trials that have shown the most promise are ones involving cancer and HIV patients. Some of the trials have combined HMB with glutamine and arginine with great results in slowing muscle wasting. I'm actually currently involved in a study evaluating the effects of HMB in combination with other amino acids when added to the diet of trauma patients. I have no idea where we currently stand but with a few more patients we'll be able to do one of our first preliminary analyses.

I've actually used HMB in the past, but it was always in combination with glutamine, creatine, protein shakes, a religious diet, and god knows what else. So, how much gain I can actually attribute to HMB is unknown.

[DBarcelo]

It is a derivative of calcium, which is why I say it's basically a type of calcium. The entire chemicle compound is "calcium Beta-Hydroxy-Beta-Methylbutyrate-Monohydrate". When the human body makes HMB, it is done by metabolizing leucine. The metabolite produced is called ketoisocaproate. When HMB is man-made, it is produced by Methylbutyrate, found in calcium. Grapefruit also contains a natural HMB.

To be perfectly honest, it sounds like your info came from some Australian research done in the late 90's.

I'm not aware of any real scientific studies on HMB besides the ones done to get it passed by the FDA as safe for human consumption.

It is supposed to help keep muscle from breaking down by inhibiting the breakdown of protein. I don't know anything about it helping the recovery of muscle cell, besides some claims made by the manufacturers (which I don't trust at all).

I've also not heard of any research done on Cancer or HIV patients. There could be, but I don't see why they would, when there are so many meds already proven to work on both of these groups. They work so well, that a lot of bodybuilders actually seek out HIV and Cancer patients for their meds. There is also little to no side effects involved with these meds that are already in place. I don't think HMB could ever compete with these other meds.

I have heard of people mixing HMB with an electrolyte like potasium, but not glutamine, nor argonine. I will admit that just because I've never heard of it doesn't mean that it doesn't exist.

I also can't help but wonder, what kind of trauma patients would be helped by HMB? And why would a hospital deal with an OTC nutritional suppliment, when it can get paid by a pharmacutical company to do the same research? Unfortunately, that's just how things work in the medical field.

I've never used HMB personally, but I do plan on doing it when I go on a prohormone cycle within the next month or two.

[dr_ma]

Since some of the people here seem to be experts on HIV research and treatment I thought they would want to know about this new product produced by Abbott Labs(thats a big pharm co). http://www.prosure.com/Juven/ Here is some news about this treatment http://www.aegis.com/news/pr/1998/PR980626.html .

[DBarcelo]

Like I wrote before, "I will admit that just because I've never heard of it doesn't mean that it doesn't exist."

Thanks for the info. I haven't gotten any word about this product yet. It's an OTC, no need for a prescription. It does look interesting though.

I should also add, I'm no expert on AIDS treatments. I just know the basics. People think that they teach you everything in great detail in med. school, but they just go into the basic things involved in all of the fields. That's why there are so many specialists out there.

It seems like a good product and I doubt it'll actually be used by many HIV or cancer patients because of it being and OTC suppliment. Most of the population get there meds through Medicaid and Medicare, they don't pay for OTC products unless they come in prescription strength.

But once again, thanks for the info.

[sinista63]

sorry for the delay in response... its been a long week and then some... haven't had much time but to work, sleep, and study.

i believe that HMB is actually produced through an oxidative process using sodium hypochlorite and diacetone alcohol. HMB is then turned into a calcium salt for stability purposes.

i remember stumbling upon this a while back when i was just doing some general HMB research. the journal article was free so i printed it up and put it away in my files. it was an investigation into high yield HMB production using microbioligical means. i did a quick (not even remotely extensive) search, just now, to see if newer methods have been developed and utilized but i was unable to find anything.

as far as the use of HMB in cancer, HIV, trauma patients, and all the other stuff, I'll give you some more info on that in the next couple of days when i have more time at my disposal.

[DBarcelo]

I was actually ablt to find a little bit about it. They are in the process of trying to get insurance companies to pay for it as a medical suppliment. Ross does a lot of work with suppliments, I use their Nepro personally.