pseudoephedrine HCl is it the same as ephedrine???

[lethalppl]

i was wondering if pseudoephedrine the same as ephedrine? if not whats different. I know they use this in E and meth. I just wondering if it the same.

[lethalppl]

u have limit of how much u can buy at once too lol

[tanto]

i never used pseudoe,i stick with ephedrine hcl.yes it's used in meth if eph is not available but there is procedure how to get rid of pseudo,and so on.dont take that as a gospel but i read somwhere that pseudoe is only 1/3 or 1/4 as potent as ephedrine hcl ,mg/mg comparison ,anyway why not go with ephedrine hcl?

[tryingtogetbig]

I believe pseudophedrine is what I take for my allergies sometimes. Loosens up my sinuses!! Makes me drowsy too. Might not do what you are wanting it to do bro!!

peace,

ttgb

[Nate_Dog]

pseudoephedrine is also used to make meth.

THey made ephedrine prescription.

Now they ID you when you want pseudoephedrine tabs from the chemist.

THIS IS IN AUSTRALIA.

[n4529359]

yeah im from australia as well we can't get ephedrine.

as a substitute ?
is pseudoepherdrine or synephrine ( citrus aurantium)
the best for wait loss??????

[Sir Savage]

Psuedoephedrine is an analog of ephedrine that is more selective in the receptors it activates. This means that it does not typically product the side-effects of ephedrine: increase in heart rate and blood pressure, etc.

It's main purpose is for allergy relief.

[Bryan2]

not as effective

[fishorcutbait]

not even close, not worth the time/conversion process

[macrophage69alpha]

Biochem Pharmacol. 1999 Sep 1;58(5):807-10. Related Articles, Links


Direct effects of ephedrine isomers on human beta-adrenergic receptor subtypes.

Vansal SS, Feller DR.

Department of Pharmacology, School of Pharmacy and National Center for the Development of Natural Products, University of Mississippi, University 38677, USA.

Ephedrine and its alkaloids are used for the treatment of asthma, nasal congestion, and obesity. Ephedrine, with two chiral centers, exists as four isomers that exhibit direct and indirect effects on both alpha- and beta-adrenergic receptors (AR). Our main goal was to study the direct effects of the ephedrine isomers on human beta1-, beta2-, and beta3-AR expressed in Chinese hamster ovary cells. Previous work indicated that the ephedrine isomers are inactive as agonists and that 1R,2S-ephedrine is more potent than the 1S,2R-isomer as an antagonist of catecholamine-induced lipolysis in rat adipose tissue (Lee et al., J Pharmacol Exp Ther 190: 249-259, 1974). Stimulation of adenylyl cyclase, associated with cyclic AMP accumulations, was measured by a luciferase reporter gene assay. On human beta1-AR, the rank order of potency (EC50 values, maximal response relative to isoproterenol = 100%) was 1R,2S-ephedrine (0.5 microM, 68%) > 1S,2R-ephedrine (72 microM, 66%) > 1S,2S-pseudoephedrine (309 microM, 53%) = 1R,2R-pseudoephedrine (1122 microM, 53%). On human beta2-AR, the rank order of potency was 1R,2S-ephedrine (0.36 microM, 78%) > 1R,2R-pseudoephedrine (7 microM, 50%) > or = 1S,2S-pseudoephedrine (10 microM, 47%) > 1S,2R-ephedrine (106 microM, 22%). Only 1R,2S-ephedrine showed significant agonist activity on human beta3-AR with an EC50 = 45 betaM and a maximal response of 31%. Our studies demonstrated that (a) stereoselective and rank order differences exist among the direct effects of ephedrine isomers; (b) 1R,2S-ephedrine is the most potent of the four ephedrine isomers on all three human beta-AR; and (c) 1R,2S- ephedrine was nearly equipotent as a beta1-/beta2-AR agonist and the only isomer possessing weak partial agonist activity on beta3-AR.

[n4529359]

what the hell does that mean