Please educate me on some bloodwork

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Questions:
How does SHBG relate to free test and total?

I would just google it but I have a reading disability where long technical explanations are hard to digest. I was hoping asking here would help me understand it better....

The equation is:

Total testosterone = Free testosterone + Albumin bound testosterone + SHBG bound testosterone

If your SHBG is low then you have less of that binding to testosterone. Total test remains the same, so you get more free testosterone.

Free testosterone is what counts really because the other ones don't bind to the androgen receptor.

Quote:

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Originally Posted by cousinmuscles

The equation is:

Total testosterone = Free testosterone + Albumin bound testosterone + SHBG bound testosterone

If your SHBG is low then you have less of that binding to testosterone. Total test remains the same, so you get more free testosterone.

Free testosterone is what counts really because the other ones don't bind to the androgen receptor.

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Thank you!