Results 1 to 17 of 17
Thread: PT-141 Nasal Spray - 20mg
-
03-16-2011, 10:36 AM #1
PT-141 Nasal Spray - 20mg
Anyone ever try this? Claim: Couple squirts up yours or your womans nose, wait 5 minutes, and bingo! Supposed to turbo charge your Libido, similar to the way Melanotan2 works. The claim continues that, unlike Cialis, there is a very high incidence of "double dipping" in a very short period of time, especially with middle aged people (where I aspire to be someday)
Thinking about getting some for my vacation this May, but wanted to hear what you horndawgs thought from personal experience.
So I kept reading on the internet, and I've read you can stack PT-141 Nasal Spray with Cialis, and evidently, they work together very well...
Additionally, I read that for post menopausal women with zero libido, there is a dramatic effect on libido and sexual activity.
The proof seems to be that almost all inventory on the internet is "temporarily out of stock"
-
03-16-2011, 02:45 PM #2
??????????????????????????????????????????????????
-
03-16-2011, 02:50 PM #3
Never heard of it. Sounds interesting tho.
-
03-16-2011, 04:08 PM #4Associate Member
- Join Date
- Aug 2010
- Posts
- 311
tried researching this product a while back. had a hard time finding credible information or sellers...
-
03-17-2011, 02:29 AM #5
we know melanotan, and malanotan2. Melanotan2 has the unusual side effect of increasing the libido (so i've heard). This is a spin off of that. I've read about 30 minutes on the internet, and all in agreement, this stuff is supposed to work.
BremelanotideFrom Wikipedia, the free encyclopedia (Redirected from PT-141)
Bremelanotide (pronounced /ˌbrɛmɨˈlænətaɪd/ ( listen)) (formerly PT-141) is a compound under drug development by Palatin Technologies as a treatment for hemorrhagic shock and reperfusion injury. It functions by activating the melanocortin receptors MC1R and MC4R, to modulate inflammation and limiting ischemia.[1] It was originally developed for use in treating sexual dysfunction but this application was temporarily discontinued in 2008, after concerns were raised over adverse side effects of increased blood pressure. Currently, Palatin is in negotiations with the FDA to resume Human Phase 2 studies using a new subcutaneous drug delivery system that appears to have little effect on blood pressure.
DevelopmentBremelanotide was developed from the peptide Melanotan II which underwent testing as a sunless tanning agent. In initial testing, Melanotan II did induce tanning but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects.[2]
In studies, bremelanotide was shown to induce lordosis in an animal model[3] and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications, it does not act upon the vascular system, but directly increases sexual desire via the nervous system.[4]A Phase III clinical trial was scheduled to begin in the first half of 2007, but was delayed until August 2007. On August 30, Palatin announced that the U.S. Food and Drug Administration had expressed serious concerns regarding the risk/benefit ratio of bremelanotide with regards to the side effect of increased blood pressure. The FDA stated that they would consider alternate uses for bremelanotide, including as a treatment for individuals who do not respond to more established ED treatments. However, On May 13, 2008, Palatin Technologies announced it had "discontinued development of Bremelanotide for the treatment of male and female sexual dysfunction" while concurrently announcing plans to develop it as a treatment for hemorrhagic shock instead.[5] The company additionally announced intentions to focus its attention on another compound, PL-6983, that causes lower blood pressure in animal models.[6] Palatin has since re-initiated Bremelanotide studies for ED and FSD using a subcutaneous delivery method. On August 12, 2009, the company announced that in a double-blind study of 54 volunteers bremelanotide failed to evoke the hypertensive side effects seen with the nasal delivery system used in prior studies, concluding that "variability of uptake" inherent in intranasal administration of the drug resulted in "increases in blood pressure and gastrointestinal events...primarily related to high plasma levels in [only] a subset of patients" and that subcutaneous administration of the drug circumvented the potential for this side effect. It is now in discussions with the FDA to resume Human Phase 2 studies utilizing subcutaneous administration.[6]
-
03-17-2011, 09:42 AM #6
Seriously... no one's tried this?
-
03-17-2011, 12:02 PM #7
bumpx2
one of you blokes must have tried this?
Cal... yer always out for the easy one... what about you?
-
03-17-2011, 12:06 PM #8
Never heard of it either.
-
03-17-2011, 12:23 PM #9
ok then. Anyone try melanotan2? does it make you h0rny???
-
03-17-2011, 12:28 PM #10
YES AND YES!
Be careful with the dose though. Took a full insulin syringe first time and had an erection that lasted almost 5 hours! Fiance was loving it though
-
03-17-2011, 12:32 PM #11
ok.. this product is derived from that, minus the darker skin. AND it is supposed to work on the ladies big time.
I'll probably go ahead and get some.... cheepest I found was $60
-
03-17-2011, 12:39 PM #12
PMing you now TR.
-
03-17-2011, 12:47 PM #13AR-Elite Hall of Famer
- Join Date
- Mar 2003
- Location
- United States
- Posts
- 10,533
- Blog Entries
- 1
PT-141 Nasal spray is a pipe dream. Out of stock as it doesnt exist, lol. Melanotan peptides are injected subq...the rest is hype.
Bremelanotide (PT-141) is a synthetic aphrodisiac that targets a couple melanocortin receptors in the brain. After subq injection users generally feel ill, depending on dosage. Sensitivity and usage of these peptides is complicated. Best to become an expert before any personal trial. Only a couple hours after a PT-141 injection do you feel anything...the window of opportunity is unique. Look out for the clinical study of subcutaneously administered bremelanotide PT-141, as a monotherapy and as a combination therapy with a PDE-5 inhibitor...believe this is currently underway.
PT-141 Doses and Experiences
Some good journalism on PT-141 in Men's Journal: http://www.mensjournal.com/the-libido-drug
500mcg-1mg PT-141 w/ 5-10mg cialis => champ
-
03-17-2011, 12:48 PM #14
i want to know more about this!!
-
03-17-2011, 01:43 PM #15
The injection is the way to go.
-
03-17-2011, 09:46 PM #16
fuk it! i ordered the nasal spray for when i go back home on vacation... my woman won't pin, but may dose nasally
-
03-17-2011, 09:49 PM #17
after reading the literature, keep in mind you have to double the dose if administering nasally.
Thread Information
Users Browsing this Thread
There are currently 1 users browsing this thread. (0 members and 1 guests)
Zebol 50 - deca?
12-10-2024, 07:18 PM in ANABOLIC STEROIDS - QUESTIONS & ANSWERS