Top 100 Selling Drugs in 2013

[kelkel]

Interesting:

http://www.medscape.com/viewarticle/820011

[austinite]

Crazy list. Cialis has actually gone up since the last time I saw a list (few years ago). It was 90-something.

I can see how year after year anti-psychotics are at the top of the board. Doctors seem to prescribe them for anything and everything, unfortunately.

Crestor is off the charts! Expensive drug.

[trikydik]

I can see how year after year anti-psychotics are at the top of the board. Doctors seem to prescribe them for anything and everything, unfortunately.

I think that's because year after year there are more psychos in the world... at least that's what the voices in my head tell me.... some of them...

[austinite]

I think that's because year after year there are more psychos in the world... at least that's what the voices in my head tell me.... some of them...

lol. Maybe. But really, GP's are out of control with these drugs. I fired the first few doctors I saw because without blood work/enough history, they offered such drugs.

[MuscleInk]

lol. Maybe. But really, GP's are out of control with these drugs. I fired the first few doctors I saw because without blood work/enough history, they offered such drugs.

That's because of larger reimbursements with pharmaceuticals.

WRT psychiatric drugs, the sad reality is the same MOAs being targeted haven't changes in the past 40+ years in part due to schedule I restrictions.

[austinite]

That's because of larger reimbursements with pharmaceuticals.

WRT psychiatric drugs, the sad reality is the same MOAs being targeted haven't changes in the past 40+ years in part due to schedule I restrictions.

exactly. Rx'ing like there's no tomorrow.

[MuscleInk]

exactly. Rx'ing like there's no tomorrow.

"A pill for every ill". I agree that many/most docs are quick to grab a prescription pad. I had this same conversation with a group of doctors last week in Boston. It's not just the MDs but a society as a whole that has come to rely on a pill to fix every problem. People generally know our diets are poor and exercise nearly nonexistent for many people. Report after report has shown that increased mental and physical exercise combined with cleaner, healthier nutrition would reduce risks for many major diseases (CVD, T2DM, obesity, cancer, AD) yet people would rather eat crap, sit on their rear ends and wait for doctors to give them a magic pill to fix everything.

I'm not saying doctors don't contribute to the problem. Clearly they do but the health care system has always reinforced treatment, not prevention, and until that changes, we will remain a pill-popping society.

[Hazard]

"A pill for every ill". I agree that many/most docs are quick to grab a prescription pad. I had this same conversation with a group of doctors last week in Boston. It's not just the MDs but a society as a whole that has come to rely on a pill to fix every problem. People generally know our diets are poor and exercise nearly nonexistent for many people. Report after report has shown that increased mental and physical exercise combined with cleaner, healthier nutrition would reduce risks for many major diseases (CVD, T2DM, obesity, cancer, AD) yet people would rather eat crap, sit on their rear ends and wait for doctors to give them a magic pill to fix everything.

I'm not saying doctors don't contribute to the problem. Clearly they do but the health care system has always reinforced treatment, not prevention, and until that changes, we will remain a pill-popping society.

Sooooo true.....

[Hazard]

There's no money in "prevention" - it costs pharmaceutical companies a TON of money to develop a drug. More money than most people probably think.....

They have to conduct research, develope the drug, study it, go through trials, FDA approval, marketing..... Etc. so of coarse they're going to milk it for every cent they can.

[MuscleInk]

There's no money in "prevention" - it costs pharmaceutical companies a TON of money to develop a drug. More money than most people probably think.....

They have to conduct research, develope the drug, study it, go through trials, FDA approval, marketing..... Etc. so of coarse they're going to milk it for every cent they can.

Approximately 10,000 new drugs annually.

5,000 make it to an IND

50-100 make it past pivotal trials (phase II)

5-10 get approved

Average R&D costs: 1.8BN

[Hazard]

Approximately 10,000 new drugs annually.

5,000 make it to an IND

50-100 make it past pivotal trials (phase II)

5-10 get approved

Average R&D costs: 1.8BN

There you go.....

Plus if they change anything on the label they have to pay a ton of money also right?

[MuscleInk]

There you go.....

Plus if they change anything on the label they have to pay a ton of money also right?

Yes, less than the 1.8BN but any unapproved indication requires approval and labeling changes - and more money.

[Black]

Kind of related. So biological gurus, how does a virus strain actually start? We know how the flu/cold/virus gets passed around, but where the hell does it start?

I just got sick and I'm developing a conspiracy theory that pharmaceutical companies are behind it. They have a team that develops the virus and then another team that releases it into the population. Think of the billions of dollars that are made during cold/flu season.

[BG]

Clearly they do but the health care system has always reinforced treatment, not prevention, and until that changes, we will remain a pill-popping society.

Truth !!!

[MuscleInk]

Kind of related. So biological gurus, how does a virus strain actually start? We know how the flu/cold/virus gets passed around, but where the hell does it start?

I just got sick and I'm developing a conspiracy theory that pharmaceutical companies are behind it. They have a team that develops the virus and then another team that releases it into the population. Think of the billions of dollars that are made during cold/flu season.

Identifying the pedigree of a virus is difficult because viruses don't leave fossil records and use various proliferating strategies to make copies of themselves within the cells they've invaded.

Some viruses even stitch their own genes into DNA of the cells they infect, making it nearly impossible to trace back the "viral ancestry". an even greater barrier to viral finger printing is that viruses don't just infect humans; they can infect basically any organism. Many viruses (influenza being one) will also mutate rapidly changing to new variants - which is why many vaccinations only work for certain strains and others are resistant.

I've had people propose the same possibilities about cancer. Some believe with all the research conducted and money spent, a cure may already exist but that there is more money in treating than healing a disease.

[Hazard]

Kind of related. So biological gurus, how does a virus strain actually start? We know how the flu/cold/virus gets passed around, but where the hell does it start?

I just got sick and I'm developing a conspiracy theory that pharmaceutical companies are behind it. They have a team that develops the virus and then another team that releases it into the population. Think of the billions of dollars that are made during cold/flu season.

http://www.nature.com/scitable/topic...ruses-14398218

[lovbyts]

Crazy list. Cialis has actually gone up since the last time I saw a list (few years ago). It was 90-something.

I can see how year after year anti-psychotics are at the top of the board. Doctors seem to prescribe them for anything and everything, unfortunately.

Crestor is off the charts! Expensive drug.

I think that's because year after year there are more psychos in the world... at least that's what the voices in my head tell me.... some of them...

lol. Maybe. But really, GP's are out of control with these drugs. I fired the first few doctors I saw because without blood work/enough history, they offered such drugs.

I did the same thing with a couple and my GP I told them to NEVER prescribe me any phyc meds, I dont care if it is also used for migraines, sleep or back/nerve issues. I made them write it in my chart.

Yeah they try to prescribe them for everything. I believe one reason is because they (government) are trying to pass laws that anyone who is prescribed phyc meds (for any reason) will be denied or have they concealed weapon permit revoked.

[Black]

Identifying the pedigree of a virus is difficult because viruses don't leave fossil records and use various proliferating strategies to make copies of themselves within the cells they've invaded.

Some viruses even stitch their own genes into DNA of the cells they infect, making it nearly impossible to trace back the "viral ancestry". an even greater barrier to viral finger printing is that viruses don't just infect humans; they can infect basically any organism. Many viruses (influenza being one) will also mutate rapidly changing to new variants - which is why many vaccinations only work for certain strains and others are resistant.

I've had people propose the same possibilities about cancer. Some believe with all the research conducted and money spent, a cure may already exist but that there is more money in treating than healing a disease.

Very informative, thanks MI.

[Black]

http://www.nature.com/scitable/topic...ruses-14398218

Good read, thanks Haz.