CBD (cannabidiol) therapeutic uses ONLY for exercise, fitness & well being.

[Sh0tsf1red]

My personal opinion on it being as honest and polite as I can be:

Cbd is just like any substance put in the body. There is an appropriate stasis amount to be administedered on an individual basis. The variance will be great and that is probably why so little is known about it.

I need to say things I cant on this thread. All I can say is that the people I know that recieve dosages all love its administration. I want to see it just the way they do but something in my chemical makeup makes me feel absolutely terrible. I have tried every possible way and always get the same result.
How many others are like me? Not many.
The use of cbd is not readily able to be narrowed down to a specific purpose dosage. Maybe more study in its reaction with other chemicals in the body will indeed reveal a specific dosage, per bloodwork, to treat/enhance a specific problem/condition.

Pehaps I could be entirely wrong and another chemical in my dosage administration was to blame for my negative reaction....

Sleep is one thing it gives me. It gives me a terrible horrible ride, straight to sleep.

I would bet your experience was based on your dose being too high

[Sh0tsf1red]

Mmmmm:

It sounds like a cure for many things. Soooo......
If I take a specific dosage to treat a specific ailment, what other ailments or non-ailments will be treated or overdosed. Such is medicine in general. "Fuck"(i have never used that word) with one chemical balance and toss around thirty others. There are zero cure-alls.

The biggest thing I see about any talk of it is that it is a miracle drug. Nay say I.

Again this is opinion to be applied to the study and simply a way of looking at all medicine in general.
Cutting nothing or no one down.

I wouldn't say it's a miracle drug yet but that's what it's trending towards. We've found out a lot about it but prohibition made it hard to study these compounds.

Today there are colleges across the USA with CBD specific drug trials and testing going on, a EU company actually just submitted a formulation for FDA approval which could be s game changer

[Couchlock]

Mmmmm:

It sounds like a cure for many things. Soooo......
If I take a specific dosage to treat a specific ailment, what other ailments or non-ailments will be treated or overdosed. Such is medicine in general. "Fuck"(i have never used that word) with one chemical balance and toss around thirty others. There are zero cure-alls.

The biggest thing I see about any talk of it is that it is a miracle drug. Nay say I.

Again this is opinion to be applied to the study and simply a way of looking at all medicine in general.
Cutting nothing or no one down.

You need to Google "brave mykala"

Tell me that don't make you cry.

And Google violent autism and CBD.

Fwiw, there is a ceiling with CBD. you will be hard pressed to take too much and get any negative effects.

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[Obs]

I would bet your experience was based on your dose being too high

Nope. Just the slightest and thats it I am gone. Tried many many times.

[Obs]

I wouldn't say it's a miracle drug yet but that's what it's trending towards. We've found out a lot about it but prohibition made it hard to study these compounds.

Today there are colleges across the USA with CBD specific drug trials and testing going on, a EU company actually just submitted a formulation for FDA approval which could be s game changer

I see what you are saying but I know a lot of folks who have had it administered for years and the have just as many or more health probs than I do. If it was a cure all it did a terrible job with 99.9% of them.

[Couchlock]

I see what you are saying but I know a lot of folks who have had it administered for years and the have just as many or more health probs than I do. If it was a cure all it did a terrible job with 99.9% of them.

Read about rick Simpson and his Phoenix tears.



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[songdog]

Nope. Just the slightest and thats it I am gone. Tried many many times.

OB you are the result of the experiment MK Ultra

[Sh0tsf1red]

OB you are the result of the experiment MK Ultra

Agreed

[Obs]

OB you are the result of the experiment MK Ultra

Agreed

If I can't be real with my family here and confess all then I run up to random strangers and blurt out embarrassing things...

[Sh0tsf1red]

The velvet fox trots at midnight

[Sh0tsf1red]

Coast to Coast AM did a great show on this topic last week, lots of good information

[Quester]

My contribution (this is from a CE course in Psychiatry, no offense is meant nor the taking any liberties suggested. I am not the author of this content hence, I do not have the ability to vet it for any of the words which we are afraid of leading to some BS. I think it is relevant because it is, perhaps, the only thing in this thread, so far, that is objective, researched, supported by rigorous academic study and therefore, it is valid. Please delete it or tell me to delete it if it is in violation.) :

Understanding Cannabis in Psychiatry: Pharmacology and Synthetic Cannabinoids
https://psychopharmacologyinstitute....abis1-ARPreach

[Obs]

My contribution (this is from a CE course in Psychiatry, no offense is meant nor the taking any liberties suggested. I am not the author of this content hence, I do not have the ability to vet it for any of the words which we are afraid of leading to some BS. I think it is relevant because it is, perhaps, the only thing in this thread, so far, that is objective, researched, supported by rigorous academic study and therefore, it is valid. Please delete it or tell me to delete it if it is in violation.) :

Understanding Cannabis in Psychiatry: Pharmacology and Synthetic Cannabinoids
https://psychopharmacologyinstitute....abis1-ARPreach

Lol! Nah! It's a cure all! Quit comparing exogenous to endogenous!
Wtf man!
You act like exogenous testosterone shuts down our natural production!

I can't help this even though I am walking a fine line because of my tren ....

I know dosers of cannibis of 50 years!
Their health is shit!
I realize I have high bp but wanna compate my gf's health to mine?
Her mothers?
Brothers?
Sisters? (Tweeker dont count)
All her friends?

I am game.

Every drug on the face of the earth has a side effect!
Cbd is not the exception.
Cbd was politicized and propaganda was built around it to support its legalization.
"Little Timmy got the rickets, little cbd an he all beddah!"

Its a game like any other.

Fuck with any balance of any chemical in the human genome and you throw off twenty others.

Warning may cause heatburn, insomnia, narcolepsy,
Fainting diarrhea (a singular symptom, you shit your pants and pass out) constipation, rapid heart rate, IHB, tacos on the porch or nothing at all.

Every drug commecially available...

But no this...
This is it.

Good post quester.

[Couchlock]

can't compare people who smoke grass to get high to people using the therapy

The doses of and needed will never be achieved by smoking rec. Pot.

There's barely .4% cbd in common stuff.

And this article is talking about synthetic cbd.

Not plant derived.

Also this article is talking about "spice" and "K2" legal herbal incense.

They are not cbd or cannabinoids



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[Obs]

Discussion is getting interesting.

[Sh0tsf1red]

My contribution (this is from a CE course in Psychiatry, no offense is meant nor the taking any liberties suggested. I am not the author of this content hence, I do not have the ability to vet it for any of the words which we are afraid of leading to some BS. I think it is relevant because it is, perhaps, the only thing in this thread, so far, that is objective, researched, supported by rigorous academic study and therefore, it is valid. Please delete it or tell me to delete it if it is in violation.) :

Understanding Cannabis in Psychiatry: Pharmacology and Synthetic Cannabinoids
https://psychopharmacologyinstitute....abis1-ARPreach

Academic studies don't prove validity friend, look at the global warming debate. Academic papers on both sides of the coin.

There is a ton of information out there, objective and university funded research. There is an USA-FDA study going on now.

Keep in mind, for the past 50 years it's been high,y restricted who even could access it to study it. Now, with some US states legalizing, more people are able to start doing actually research. We are at the tip of the iceberg so to speak.

[tarmyg]

Academic studies don't prove validity friend, look at the global warming debate. Academic papers on both sides of the coin.

There is a ton of information out there, objective and university funded research. There is an USA-FDA study going on now.

Keep in mind, for the past 50 years it's been high,y restricted who even could access it to study it. Now, with some US states legalizing, more people are able to start doing actually research. We are at the tip of the iceberg so to speak.

Unless I am miunderstanding Quester (which is plausible) this is the current accepted working theory (In the same way gravity is the current working theory). I am confused why you would negate Academic studies and in the next sentence refeer to some. I am probably just misunderstanding and for that I apologies.

[Quester]

Academic studies don't prove validity friend, look at the global warming debate. Academic papers on both sides of the coin.

There is a ton of information out there, objective and university funded research. There is an USA-FDA study going on now.

Keep in mind, for the past 50 years it's been high,y restricted who even could access it to study it. Now, with some US states legalizing, more people are able to start doing actually research. We are at the tip of the iceberg so to speak.

Every single bit of technology, science, idea, and belief is supported by academic rigor. It is the only way our society has of showing validity. The vast majority of information available on this forum is supported by academic cancer.
The difference between pharmacological to treat cholesterol, epilepsy, parkinsons and CBD's, fish oil, glutamine/chondritin is that the pharmacologicals have been rigorously studied by experts who have spent decades in the field, used empirical and reproducible methods (experimentation, statistical analysis, historical and longitudinal studies, meta analysis) to produce and submit a paper on their findings that is vigorously reviewed (with prejudice) by other people who have spent decades learning about the same thing and whose reputations are on the line. DR OZ can say that CBD's are great but it will not affect his ratings if he is proven wrong.
Furthermore, I am not agianst CBDs but I have read not one submission to this thread that offers any substance other than the one that I just posted. If your topic has legitimacy, show it. Show us the proof. Where is the information coming from? Ask Kel about TRT and he can point to a study. Ask a CBD perosn and he does what, responds with a defensive posture?

[Quester]

Don't say "there is a study," if you can show the study. The accepted practice is just as it has been on this forum in the past: "the study posted in link below states..."
By all means, teach me, my mind is clear and my ears are open. Use this opportunity. I am your student, accept the responsibility by showing accountability.
The message isn't directed at Shots specifically, it is directed at the thread itself.
I am a SOCIAL LIBERTARIAN and support CBDs and the stuff it is derived from. Teach me so that I can meaningfully support your cause.

[Quester]

*Correction: I support the legality, not the use.

[Couchlock]

Unless I am miunderstanding Quester (which is plausible) this is the current accepted working theory (In the same way gravity is the current working theory). I am confused why you would negate Academic studies and in the next sentence refeer to some. I am probably just misunderstanding and for that I apologies.

The study is about synthetic cannabinoids. Which are not even cannabinoids, but substances that have an affinity for cb1 and cb2 receptors I.E. "synthetic weed" that was outlawed in a few states because of people dying,
.


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[Quester]

Right, but it is related and it is science not conjecture, or opinion. The message from the study: CBDs can be created synthetically and made potent, in high doses they have toxic effects. It isn't saying that at low doses, they are toxic but it is not saying that at low doses they are not toxic. It is simply saying that at high doses, they are toxic. If something is toxic at any dose, it likely has similar properties at lower doses. I.E. there is a spectrum, and it is normally a direct relationship, however, some chemicals do follow an inverse relationship. At low doses they do the opposite of what they do at high doses. Is CBDs one of those? IDK, NO STUDIES HAVE BEEN SHOWN...

[Couchlock]

Right, but it is related and it is science not conjecture, or opinion. The message from the study: CBDs can be created synthetically and made potent, in high doses they have toxic effects. It isn't saying that at low doses, they are toxic but it is not saying that at low doses they are not toxic. It is simply saying that at high doses, they are toxic. If something is toxic at any dose, it likely has similar properties at lower doses. I.E. there is a spectrum, and it is normally a direct relationship, however, some chemicals do follow an inverse relationship. At low doses they do the opposite of what they do at high doses. Is CBDs one of those? IDK, NO STUDIES HAVE BEEN SHOWN...

Not the same


There's a reason why stuff like sativex and marinol provide next to no relief or therapeutic benefits compared to naturally derived compounds.

This is almost baiting the conversation to the banned derivative.

Please limit duscusdion to CBD ONLY

That study focused on the banned aspect as well

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[Quester]

Your adherence to the agreement is commendable. No attempt was made to violate that, you've done a good job maintaining the agreement. My post was about the psycho (my area)-pharmacological effects of the ingestion of high potency CBD's. If it is in violation of the agreement, have it removed or ask me to do it. Out of respect, I'll do so as soon as I see the request. My motivation to post it was to motivate the rest of you to honor the implicit part of the agreement. Just as we do in the rest of the forum, post sources, post support, reference your comments, Please. There may be legitimate uses for CBDs, prove it so it will matter when you state it.

[Sh0tsf1red]

Your adherence to the agreement is commendable. No attempt was made to violate that, you've done a good job maintaining the agreement. My post was about the psycho (my area)-pharmacological effects of the ingestion of high potency CBD's. If it is in violation of the agreement, have it removed or ask me to do it. Out of respect, I'll do so as soon as I see the request. My motivation to post it was to motivate the rest of you to honor the implicit part of the agreement. Just as we do in the rest of the forum, post sources, post support, reference your comments, Please. There may be legitimate uses for CBDs, prove it so it will matter when you state it.

Couch is good with links do I imagine he will post them soon, I don't know how to post links off the device I use for this forum but you can search and find reputable studies.

There are a few drugs working their way throw federal approval process, you can find that fda info packets which have all their clinical data, trials, etc.

A European drug company has a CBD drug that just made some big progress that was in the news cycle lately, major drug company too

[Couchlock]

Your adherence to the agreement is commendable. No attempt was made to violate that, you've done a good job maintaining the agreement. My post was about the psycho (my area)-pharmacological effects of the ingestion of high potency CBD's. If it is in violation of the agreement, have it removed or ask me to do it. Out of respect, I'll do so as soon as I see the request. My motivation to post it was to motivate the rest of you to honor the implicit part of the agreement. Just as we do in the rest of the forum, post sources, post support, reference your comments, Please. There may be legitimate uses for CBDs, prove it so it will matter when you state it.

I hear ya. I'd like to discuss all cannabinoids. But can't.

At times its hard to just focus on one singular cannabinoid, being they work synergistically together.

[Quester]

That sounds great...can you two show some studies I can read about that?

[Couchlock]

That sounds great...can you two show some studies I can read about that?

What exactly do you want to read about it regarding?

[Couchlock]

That sounds great...can you two show some studies I can read about that?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189631/

https://www.ncbi.nlm.nih.gov/m/pubmed/22716160/

https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq

[Quester]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189631/

https://www.ncbi.nlm.nih.gov/m/pubmed/22716160/

https://www.cancer.gov/about-cancer/...p/cannabis-pdq

Couch I read these with the intention of offering some type of positive support because I appreciate that you went to the effort. Unfortunately the studies do not allow me to do that.
From the first article:
"Conclusions
At this time, there does seem to be a growing body of basic pharmacologic data suggesting there may be a role for CBD, especially in the treatment of refractory epilepsy. However, given the lack of well-controlled trials, we must also ask if we are getting ahead of ourselves. Clearly, this is an emotionally and politically charged issue. If this were any other uninvestigated pharmaceutical compound, would we feel as compelled to make the agent widely available before statistically valid class 1 evidence was available for review? Until data from well-designed clinical trials are available and reliable, and standardized CBD products that are produced using GMP are available, caution must be exercised in any consideration of using CBD for the treatment of epilepsy. In the meantime, based upon promising preliminary data, further clinical research should be wholeheartedly pursued."
To sum up:------
That article was about the use of CBDs for epilepsy. That article surveyed all other articles and studies available and concluded that not enough evidence existed to support the use of CBDs for epilepsy nor the study of it for that purpose in lieu of other therapeutic means for treating epilepsy.-----
The second article is more positive, although only the abstract is available: (from the abstratct)
"Although the mechanisms of the antipsychotic properties are still not fully understood, we propose a hypothesis that could have a heuristic value to inspire new studies. These results support the idea that CBD may be a future therapeutic option in psychosis, in general and in schizophrenia, in particular."-----
To sum up:-------
The article suggests that CBDs are worthy of being considered as a subject to begin studying for the purposes of investigating CBDs for their antipsychotic (think Charles Manson) and anti-schizophrenic (think Ted Bundy) properties.
The third website (not an article or study but it is from a credible source).-----
"Cannabinoids may have benefits in the treatment of cancer-related side effects."------
To sum up:-------
The website spends more than 500 characters talking about the negatives and then says that CBDs may have benefits in its effects as an agent of palatave care.-----
----
My take, CB1 and CB2 modulate pain through their effect on our endocanibinoid receptors. This raises quality of live for those who suffer from chronic pain associated with debilitating diseases. There must be something from the source of the first two studies to support that.-------
Now, does that have an application to bodybuilding? Bodybuilders are not in the same category of people with epilepsy, display psychotic behavior, display schizophrenic behavior, and suffer from Cancer. One main reason, they have agency, the ability to change themselves, they own their future.-------
In the context of one who suffers the Severe pain that accompanies a debilitating disease which one knows will kill them, significantly impairs their daily living to the point of inhibiting their ability to enjoy the basic aspects of life: growth, family, community, worship, friendship, work, accomplishment, love, reproduction, lust...walking your dog... Those factors require a holistic approach to repair that includes fighting depression, severe pain, intense loneliness, hopelessness, spiritual distress. CBD's, and anything else, should definitely be condsidered.-----
Currently, I am doing clinicals at a nursing home. There are patients there who have severe (stage 4) pressure ulcers, they will likely die from these and the primary reasons for which they arrived. They should have whatever they want...anything.
Are there any studies about the application of CBDs to enhance life for regular people, and better, to enhance the life of bodybuilders, or perform a function (like recuperation) in bodybuilding?-----

[Oliver47]

I have been using Medical marijuana for just over two weeks now. Impact on anxiety is certainly significant. Much less frantic feeling. Way more focus and concentration. Mood dramatically improved.