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Thread: Interesting Drug Facts...
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01-28-2004, 11:18 AM #1
Interesting Drug Facts...
Interesting Facts on Drug Testing
****DRUG TESTS FACTS****
http://207.198.64.252/zbd.html
First, let's dispel a myth. There is no single drug test that will detect each and every substance consumed by you. Each drug must be tested for independently. The National Institute on Drug Abuse (NIDA) specifies that the minimum test be for the following 5 categories (this is commonly referred to as a 5 panel test by the drug testing industry):
-Amphetamines and methamphetamines (Ectasy will show up here, as well as the diet pill Phentermine)
-Cannabinoids (Marijuana and Hashish)
-Cocaine
-Opiates (this includes Heroin, Opium, Morphine and Codeine)
-Phencyclidine (commonly known as PCP and Angel Dust)
• While this is usually the minimal test, additional testing can include:
-Anabolic steroids (Stanazolol, Nandrolene, etc.)
-Barbituates (includes Amytal, Fioricet, Nembutal, Seconal)
-Benzodiazepines (includes Ativan, Klonapin, Librium, Valium, Xanax)
-Methadone (used to overcome withdrawal symptoms from Opiates)
-Methaqualone (Quaaludes)
-Propoxyphene (includes Darvon and Darvocet)
While not tested for, under NIDA guidelines, here's info on alcohol that might be helpful. It is usually metabolized and undetectable after 18 to 24 hours. If you ever wonder what your blood alcohol might be, after a few drinks, try this link http://home.earthlink.net/~dessyra/form/bac_calc.htm
DETECTION TIMES IN URINE
• Amphetamines and Methamphetamines---------------------------1 to 4 days
• Anabolic steroids (orally)------------------------------------------14 to 28 days
• Anabolic steroids (parenterally)----------------------------------30 to 60 days
• Barbiturates----------------------------------------------------------2 to 3 days
• Benzodiazepines-----------------------------------------------------21 to 30 days
• Cannabinoids, Marijuana
Single use---------------------------------------- 3 to 7 days*
Moderate use (once or twice a week)--------21 to 30 days*
Chronic use (at least once a day)-------------up to 60 days*
(*These times relate to outdoor grown "street" marijuana, which has a typical THC level of 2% to 3%. Indoor grown "cryppie" can have THC levels as high as 7% to 10%, so keep that in mind.)
• Cocaine-------------------------------------1 to 3 days
• Codeine-------------------------------------2 to 4 days
• Methadone---------------------------------4 to 7 days
• Methaqualone------------------------------2 to 4 days
• Opiates-------------------------------------2 to 4 days**
(**Hydrocodone and Oxycodone are synthetic versions of morphine, found in pain medications such as Lorcet, OxyCotin, Perocet, Vicodin, etc. Normal dosage of these is not usually detectable as an opiate, but excessive use can be detected. As uses of these medications become more wide spread, however, specific tests for synthetic morphine are being added to the opiates list.)
• Phencyclidine------------------------------3 to 5 days
FACTORS AFFECTING DETECTION TIMES
• History of use (the greater the frequency of use, the longer the detection period)
• Metabolism (a faster metabolism gets rid of the substance more easily, so exercise)
• Body weight (the more body fat, the longer the detection time)
• Potency of drug (this is obvious)
• Tolerance (prolonged use brings higher tolerance and shorter detection times, as the body metabolizes the substance more quickly)
To view laws for your particular state, click this link http://www.ohsinc.com/laws_state_dr...g_laws_SAID.htm
Drug testing basically falls under two categories, "screening" and "presumptive". Screening, as the name implies, is used to screen out drug users, either thru pre-employment testing or random testing. It is intended to be a deterrent to drug use. The most common screen test is urine analysis, although a hair test is sometimes used.
Presumptive testing is used when you actions raise suspicions of drug use. These suspicions can range from slurred speech to being involved in an accident. A blood test is usually administered, in these cases, but sometimes saliva testing will be used.
By whatever method a drug is taken, it winds up in your bloodstream, where it gets converted to metabolites. The traces of most drug metabolites become undetectable, in urine or blood tests, within a few days, but marijuana presents special problems. While it is the most popular drug and thus the most commonly tested for drug, it is also the drug that hangs around the longest in our bodies.
It contains a psychoactive compound, known as THC, which becomes attached to fat cells in our bodies. These fat cells slowly release the THC back into the blood stream, where it is then excreted via urine. It is still being released days after the last use of marijuana. The length of time, it is detectable in urine, depends on the potency and how often it is used. This is why a casual user can have undetectable levels after just a few days, while a heavy user may have to wait up to 30 to 60 days.
Additional factors affecting detection times are weight and metabolism. The bigger you are, the more fat cells you have, making you a bigger warehouse for THC. The higher your metabolism, the faster you burn these fat cells, ridding yourself of the drug metabolites. Being skinny and hyper is a definite advantage.
Other drugs that hang around for a long time are sedative benzodiazepines, such as Valium, Xanax and Librium. This is okay. Just be able to produce a current prescription before the test.
Hair testing presents a more difficult problem and a common question is how drugs even get into your hair. Well those drug metabolites, running around in your blood, are getting absorbed by the hair follicles in your scalp. As your hair grows out of those follicles the hair strands are also picking up those traces of drug metabolites. This is true for any and all absorbed drugs.
Your hair retains a history of drug use for a long time. A strand of hair grows an average of 1/4" per month, so just a 4" length can show drug use as far back as 8 months. Shampoos bleach and dyes are not effective in masking the drugs, but will only reduce the metabolite level embedded in the hair, never eliminating it.
African-Americans are at a particular disadvantage with hair testing. Because of the melanin in their hair, which really soaks up the drug metabolites, they can be up to 50 times more likely to test positive.
Hair absorption of second hand smoke is not likely unless you're in a very confined area, like a car, and there is an extreme concentration of smoke. Simply being in a room, club, bar, etc., where there is smoke, is not a problem, so don't use that as an excuse.
As previously mentioned, the most common test is urine analysis. It involves the use of a chemical compounds called immunoassays. These are special antibodies that are attracted to the specific drug or drugs, for which a person is being tested.
If drugs are present, in the urine, these antibodies bind to the drug molecule and this binding is detectable with the appropriate laboratory test equipment.
The EMIT (Enzyme Multiplied Immunoassay Test) is the prevailing test procedure. This is primarily because it is the least expensive method, costing $60 to $100. It is also the least reliable test. The immunoassays used, often have trouble distinguishing between the drugs for which they are searching and other substances in the urine sample. They can bind with numerous over-the-counter and prescription medications, giving a "false positive" result.
Other immunoassay tests are the RIA (Radioimmunoassay) and FPITA (Fluorescent Polarization Immunoassay). The RIA procedure is widely used by the U.S. military. While these tests are more costly, sensitive and selective, they are far from being infallible. The inherent problem, with any immunoassay test, is the inability to absolutely distinguish between specific drugs, whether it be illicit drugs, prescription medication or over-the-counter medication.
If you should test positive by immunoassay testing, demand confirmation by a more sophisticated method. Immunoassay test are so unreliable, the results are not even admissible in a court of law. They are wrong as much as 25% of the time. The laboratories won't admit this and your employer or pending employer are just going to believe whatever pitch the laboratory gives them. Don't be afraid to challenge the test results!
To top all of this off, you are probably being tested by a laboratory that put in the lowest bid and does not have to meet any particular guidelines. This is what you're up against. Only federal employees and those engaged in public transportation are required to be tested by National Institute of Drug Abuse certificated laboratories.
More expensive and refined testing procedures are GC (Gas Chromatography), GLC (Gas Liquid Chromatography) and GC/MS (Gas Chromatography/Mass Spectrometry). GC/MS is by far the most precise testing method and the results meet forensic specifications and can be used in court. If you are positive, GC/MS will get you! This test can also be used on all body fluids.
Blood testing, most often used when there is an accident, will show the real level of drug intoxication, whereas other testing methods only show the presence of drugs. This is important to remember because being tested positive, by other than a blood or saliva test, does not mean you were under the influence of drugs at the time of the test.
Just as a note, all test results can be flawed by such things as incorrectly calibrated test equipment, contaminated samples, incorrect interpretation of results, clerical errors and just about any other way a person can make a mistake.
By the way, most of the advertised cleansers are simply high priced diuretics or some type of herbal tea. Drinking alot of cranberry juice will work just as well
If it's test day, don't eat any poppy seed bagels for breakfast. Recently digested poppy seeds can make you look like you just came from an opium den.
Even if you're clean, you're fighting an uphill battle. Many prescription and over-the-counter medications can cause "false positive" results. Some of the categories include:
-headache and pain medications that contain ibuprofen
-allergy medications
-cold remedies
-PMS medications
-sleep aids
-sinus medications
-appetite suppressants
-nasal and throat sprays
-nasal inhalers
-pain medication
-antibiotics--(amoxicillin is notorious for giving a "false positive" for cocaine use.. also just having diabetes or a kidney or liver infection or disease can show a "false positive"..)
-kidney infection medications
-antidepressants
So it's obviously necessary to list any and all medications, taken within the last 30 days. If you have been taking anything that requires a doctor's prescription, be sure you'll able to provide proof, such as the bottle, etc. Don't forget that those sedative benzodiazepines, such as Valium, Xanax and Librium, hang around for up to 30 days.
One strategy, people consider before a drug test, is to substitute or alter the urine sample. Be aware that if you are caught, there can be serious consequences. In some states it is a criminal offense.
If your job application is rejected. You may never know the test results, as you will probably be given some other excuse. If you are told that the test was "positive" you can ask for a confirming test. They may or may comply; this can depend on how badly they want your services. Don't think that you are buying time and can give another sample. Most likely, your original sample has been stored and will be tested again. Try to find out if this is the case.
Now suppose your present employer, through random testing, gets you, what happens? They are legally required to give you a confirming test only if you request it.
Employers are becoming less aggressive about termination of those who test "positive" unless your safety, the safety of your follow workers or the safety of the public is at risk. Some companies may offer a suspension, rehab or some other compromise. The more valued you are, as an employee, the more they will work with you.
The bottom line is that there are no absolute guarantees that you will pass a drug test. Follow the procedures, we have laid out, and you will definitely improve your odds. This is especially true if you consider yourself borderline.
If you want to fight the system, then there is always legal recourse. Some of the below links will direct you to that area. Of special interest may be the ACLU and NORML sites.
We think we have laid out the truth, without any hype, and sincerely hope that you will benefit by this. Just e-mail us if you have any thoughts or questions. We'll do our best to help.
Our e-mail address is [email protected]
SITES FOR FURTHER EXPLORATION http://www.erowid.org/psychoactives/psychoactives.shtml
http://www.norml.org/
http://www.hightimes.com/
http://www.geocities.com/SoHo/Square/4085/findex.htm
http://www.mapinc.org/index.htm
http://www2.druginfo.org/orgs/dsi/
http://www.drcnet.org/
http://www.aclu.org/index.html
http://www.drugtestpolicy.com/wwwboard1/index.htm
http://www.totse.com/en/drugs/index.html
http://herb.com/wwwboard/wwwboard.html
http://www.studentadvantage.com/
Hope this helps....
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01-28-2004, 11:27 AM #2
Once again...great information MRKD!
peace,
ttgb
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01-28-2004, 11:44 AM #3Swellin Guest
Nice post.
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01-28-2004, 12:17 PM #4
That was extremely informative...........I read that thing through and through.
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01-28-2004, 12:21 PM #5
IM printing it just for future refrence 8)
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01-28-2004, 12:46 PM #6
Just looking out for the Awesome Member's and Staff here, You all Rock...
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01-28-2004, 12:57 PM #7
Should be made a sticky
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01-28-2004, 01:01 PM #8Originally Posted by mass junkie
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01-28-2004, 03:17 PM #9
Actually the more frequent drug users get the drugs out of their system more quickly than the once-in-a-while users.
As far as the gas chromotography, maybe they have very, very good equipment, but its usually pretty unreliable, but there's obviously many other methods to still catch you, follicle test probably being the best.
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01-28-2004, 06:48 PM #10
Yea a Sticky, I agree... Just Looking out...
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01-28-2004, 07:26 PM #11
That's some solid ass info bro... Good stuff...
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01-29-2004, 08:27 AM #12
when people use GC-MS, sometimes they use something called Dual GC-MS. Not only can it be used for drug testing (the recent olympic doping scandal was found out by this method by a lab in cali), but medical diagnostics also use it. simply put, it reduces the chance that interferences will occur by running the sample through two different GC columns, each with a different polarity so that the samples will be separated differently. its actually quite accurate as these things go.
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01-29-2004, 11:57 AM #13
sticky! very good info
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01-29-2004, 01:06 PM #14
great info...but as i recall, certain AS (or their metabolites) can be detected in blood for much longer...just to keep that in mind
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01-29-2004, 01:41 PM #15
(*These times relate to outdoor grown "street" marijuana, which has a typical THC level of 2% to 3%. Indoor grown "cryppie" can have THC levels as high as 7% to 10%, so keep that in mind.)
Home grown ak-47 has a THC level of 20%
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01-31-2004, 11:27 PM #16Originally Posted by saboudian
indeed.... here is some additional info on that...
Detection of anabolic steroids in head hair.
Deng XS, Kurosu A, Pounder DJ.
Department of Forensic Medicine, University of Dundee, Royal Infirmary, Scotland.
We developed a gas chromatography/mass spectrometry method for detection and quantitation of anabolic steroids in head hair. Following alkaline digestion and solid-phase extraction, the MO-TMS derivatives gave a specific fragmentation pattern with EI ionization. For stanozolol , the TMS-HFBA derivative showed several diagnostic ions. For androstanolone, mestanolone (methylandrostanolone), and oxymetholone two chromatographic peaks for cis and trans isomers of derivatives were seen. Recoveries were 35 to 45% for androstanolone, oxymetholone, chlorotestosterone-acetate, dehydromethyltestosterone, dehydrotestosterone, fluoxymesterone, mestanolone, methyltestosterone , and nandrolone ; 52% for mesterolone, trenbolone ; 65% for bolasterone; 24% for methenolone and 17% for stanozolol. Limits of detection were 0.002 to 0.05 ng/mg and of quantitation were 0.02 to 0.1 ng/mg. Seven white male steroid abusers provided head hair samples (10 to 63 mg) and urine. In the hair samples, methyltestosterone was detected in two (confirmed in urine); nandrolone in two (also confirmed in urine); dehydromethyltestosterone in four (but not found in urine); and clenbuterol in one (but not in urine). Oxymethalone was found in urine in one, but not in the hair. One abuser had high levels of testosterone : 0.15 ng/mg hair, and 1190 ng/mL urine. We conclude that head hair analysis has considerable potential for the detection and monitoring of steroid abuse .
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