anybody know about.......

[thecoachman]

got a new "LIST" today and these were on it:

Nitrotrain (search yeilded only 4 dead threads, no info)
Bprenorphene
Temgesic
Talwin

I think that last ones are pain killer. If you have info on them I would really appreciate it. I have severe pain in my knees after a good leg day from Arthritis. Being a waiter doesn't help that problem either.

thanks again guys/gals

'coach

[gymnut4u]

Buprenorphine treatment
of refractory depression
by
Bodkin JA, Zornberg GL, Lukas SE, Cole JO
McLean Hospital, Consolidated Department of Psychiatry,
Harvard Medical School, Belmont, MA 02178, USA.
J Clin Psychopharmacol 1995 Feb; 15(1):49-57

ABSTRACT
Opiates were used to treat major depression until the mid-1950s. The advent of opioids with mixed agonist-antagonist or partial agonist activity, with reduced dependence and abuse liabilities, has made possible the reevaluation of opioids for this indication. This is of potential importance for the population of depressed patients who are unresponsive to or intolerant of conventional antidepressant agents. Ten subjects with treatment-refractory, unipolar, nonpsychotic, major depression were treated with the opioid partial agonist buprenorphine in an open-label study. Three subjects were unable to tolerate more than two doses because of side effects including malaise, nausea, and dysphoria. The remaining seven completed 4 to 6 weeks of treatment and as a group showed clinically striking improvement in both subjective and objective measures of depression. Much of this improvement was observed by the end of 1 week of treatment and persisted throughout the trial. Four subjects achieved complete remission of symptoms by the end of the trial (Hamilton Rating Scale for Depression scores < or = 6), two were moderately improved, and one deteriorated. These findings suggest a possible role for buprenorphine in treating refractory depression

[gymnut4u]

Temgesic (buprenorphine hydrochloride) is an opiate acting as a central nervous sytem depressant analgesic. It comes in white tablets of 200 mcgs and 400 mcgs as well as ampoules for injection

[gymnut4u]

TALWIN® Tablets
Sanofi
Pentazocine HCl
Analgesic

Action And Clinical Pharmacology: Pentazocine is a member of the benzazocine series of synthetic benzomorphans. It produces both analgesic (agonist) and narcotic antagonist effects. The analgesic effect of 50 mg pentazocine administered orally is approximately equivalent to 60 mg codeine. Pentazocine also produces a sedative effect.

The onset of analgesia following oral administration of pentazocine can occur within 15 to 30 minutes and the duration of effect is usually 3 hours or longer. The onset and duration of analgesia are, in part, related to the dose and severity of pretreatment pain. Peak serum levels of pentazocine occur between 1 and 3 hours after oral administration. Approximately 60% of an oral dose is eliminated in the urine within 24 hours. There is considerable variability between individuals in terms of the rate of pentazocine metobolism which may also account for the variability in analgesic response.

Indications And Clinical Uses: For the relief of chronic or acute pain of moderate to severe degree.

[the original jason]

temgesic works very similar to heroin and most people on the big H use temgesic to from my memory it is took by being held under the tongue and gives similar relaxing effect to heroin

peace

[hammerhead]

Talwin is Pentacozine, a methadone-derived analgesic. It is roughly equivalent in effectiveness to codeine.

[thecoachman]

you guys are the best!!!!!

Were did some of you guys get that med. info?
Is there a book or site?

thanks again....

this site proves to be VERY VALUABLE, again!

best board there ever: is, was, ever will be.....

thanks

'coach