What kind of effects does rec drugs like ecstacy or ketamine do while on a cycle? My friend just started his first cycle and I told him htat hes gonna have to knock that crap off. Unfortunately he doesnt listen to me and gets f**ked up every weekend and then continues to tell me he doesnt eat ANYTHING the next day cause his appetite is too suppressed. I'm just mad cause I tell him what to do and not to do and try to give him sound advice and he does the opposite of what I tell him.