Dinistenile What is it?

[Mike.B]

Can someone tell me what this is, and does?
Denistenile. (from Spain)
Dihidroepiandrosterona. DCI.
6 brown amps to a box filled with powder
6 bottles 3ml water solution to mix.

[Mike.B]

Sorry, that's 2 bottles of water solution!
AND white powder in the amps, like HGH!

[jbrand]

Originally posted by Mike.B
Can someone tell me what this is, and does?
Denistenile. (from Spain)
Dihidroepiandrosterona. DCI.
6 brown amps to a box filled with powder
6 bottles 3ml water solution to mix.

Sounds like DHEA to me, the chemical that is. Why they are in vials with water is beyond me.

[gymnut4u]

Taken from med text !

Dehydroepiandrosterone (DHEA) is a metabolite on the steroidogenic
pathway between cholesterol and the sex steroids . In the human and
other primates, the adrenal is the most prolific source of DHEA, with
the sulfated derivative, DHEAS, synthesized primarily in hepatic and
adrenal tissues. (For the remainder of this Announcement, the
abbreviation DHEA refers to DHEA and/or DHEA sulfate collectively.)
In primates, DHEA is present in levels considerably higher than the
other steroid metabolites of cholesterol. Many cross-sectional
studies have documented that serum DHEA levels in humans and other
primates is developmentally regulated, i.e., DHEA increases during
pregnancy to a high level prior to birth, drops precipitously at
birth, increases at adrenarche to a maximum around the early 20's,
then declines gradually into old age (while other major adrenal
steroids, glucocorticoids, remain relatively unchanged with age),
reaching about 10-20% of its peak value around age 80.

Clinical and epidemiologic studies on the relationship of DHEA levels
to diseases and other health outcomes have not had consistent
results. Some prospective studies have found an inverse relationship
between DHEA levels and risk for cardiovascular disease risk in men,
while others have found no relationship. A case-control study found
low DHEA levels in Alzheimer's disease patients relative to
age-matched controls, while another did not. Other cross-sectional
studies have reported associations between low DHEA levels and
dyspnea, depressive symptoms, impairments in activities of daily
living in older women (but not men), elevated mortality risk in older
men (but not women), and rheumatoid arthritis, but there have not
been reports of studies to replicate these findings. On the other
hand, a case-control study found higher DHEA levels in cases of
ovarian cancer relative to controls, and two studies found an
association between high DHEA levels and hypertension, while others
found no relationship. Most of these studies had very limited power
to address the potential confounding effects of covariates which
could contribute to spurious associations (or lack of association)
between DHEA levels and the outcomes reported.

Animal studies, generally performed in species in which endogenous
DHEA levels are normally relatively low and may not change
substantially with age, and involving dietary DHEA at very high
levels for most studies, show delayed tumor formation, prevention of
atherosclerosis, weight loss in obese animals and, in general,
retardation of the development of many chronic age-related pathologic
changes.

The conference "Dehydroepiandrosterone (DHEA) and Aging", supported
in part by the NIH and sponsored by the New York Academy of Sciences,
was held in Washington, DC in June, 1995 (Bellino, FL, Daynes, RA,
Hornsby, PJ, Lavrin, DH and Nestler, JE, eds. Annals of the New York
Academy of Sciences, vol 774, New York, 1995). The purpose of the
conference was to define a future research agenda based on a review
of the current status of a variety of ongoing investigations into a)
mechanisms of the apparent steady decline of DHEA with age from the
mid-twenties to old age, b) epidemiologic studies suggesting positive
health benefits for individuals with higher levels of DHEA for their
age group and clinical studies of effects in individuals supplemented
with DHEA in the short-term studies, and c) health effects of
supplementary DHEA in animal studies.