well nolva is a sem which is in itself a weak estrogen and not suitable for actually causeing the body to make more test this post should help you out I wrote it for another board
First well look at Tribulus this particular Suppliment is questionable although many take this root of a plant native to asia in terms of hopeing for test production The scientific evidence to back it up just isnt there.
I can say from personal experience that it does personally raise my libido but there is no way to really prove that it does this way by terms of raising LH hormone thus increasing testosterone production.Studies show that Tribulus acts as such a precursor to DHEA and the only real thing that can be determined is that it makes castrated rats really horny
But if you are going to use it in hopes of test production use it at a 5 Gram or higher dose to notice any significant effects.
Tongat Ali is a shrub tree that grows in maylasia which is mainly used as a male aphrodisiac which I will totally agree works for that purpose but is this because of a direct rise in Test levels again there is not enough scientific data to back this claim up
Take in 1-2 G doses
ZMA is next
Next we’ll take a look at ZMA, a combination of Zinc Monomethionine Aspartate (30mg), Magnesium Aspartate (450 mg) and Vitamin B-6 (10.5 mg). The theory behind ZMA is simple: zinc and magnesium are important in the production of steroids and B-6 is important in energy production, two things crucial to athletes. If you become deficient in any of the ingredients in ZMA you see a subsequent decrease in androgen production and performance in general--and there is evidence that a number of diets may be deficient in all three.
In vitro research clearly illustrates how supplementation with magnesium can decrease the amount of testosterone bound to human serum albumin, thus, increasing free testosterone.
Another interesting effect of both zinc and magnesium is their influence on cortisol secretion. A study conducted with oral dosages of zinc ranging from 25 mg to 50 mg showed an inhibitory affect on cortisol secretion over 240 minutes . This evidence suggests that ZMA supplementation could cause performance increases and an increase in testosterone via the decrease of the catabolic hormone cortisol.
From all of the research available today ZMA can offer a raise in testosterone to sunjects with deficient levels. But the likelihood of raising testosterone production above physiological maximums seems unlikely.So supplimenting with ZMA should be used IMO as more of a prevention method to ensure peak testosterone levels are maintained.
Then we are left with Androstenetrione.
Androstenetrione marketed by Ergopharm under 6-oxo works as a suicide inhibitor to aromatase. Aromatase is the enzyme responsible for converting Testosterone into Estrogen. Now the theory here is clear, reduce enough estrogen in the hypothalumus and the body will try and counteract this by producing more androgens which are the precursors to estrogen. This is the bodys only way at producing a high level of estrogen is to produce more testosterone in order to aromatase into estrogen.
But considering the new anti E is out on the market that puts 6oxo to shame would be ATD it is very close in structure to the precription anti E exemestane and works very very well.
Now there is a new gem on the market that is currently on its beta testing phase it is called AcTivaTe and is being marketed by Designer Suppliments although this product does not directly increase Testosterone production it does increase actual useable test in the body by binding to SHBG to acheive more free test and therfore create an environment for enhanced muscle growth.
There are 4 proteins that testosterone can be bound to...they include:
albumin
SHBG
transcortin
transferrin
OR the testosterone can be a free/unbound hormone.
Both free/unbound and albumin bound testosterone are biologically active, which is comprised of 33 to 54% of the total circulating testosterone. The SHBG is not availiable for physiological use, which is comprised of 44 to 65% of circulating testosterone.
Transcortin is a corticosteroid binding globulin and when bound to testosterone is a measure of estrogenicity.
Transferrin increase is associated with estrogen excess.
As you age, there is a decrease in synthesis of androgens by the Leydig cells in the testes and the zona reticularis of the adrenal cortex, with a increase in SHBG production by the liver.
What we primarly want to do is lower SHBG levels or prevent them from binding to testosterone and increase the free/unbound testosterone and the albumin bound testosterone.
Here is a graph showing how the product works
taken from Myostatin on anabolicminds
So Trib really has no scientific data to back up the claims of increased test production
ZMA should be used more as a prevention method to ensure that optimal levels of test are maintained.
And Androstenetrione shows the most promise for actually increasing ones test levels beyond normal parameters.
So the key palyers here are activaTe by Designer supps and either a traditional AI ie arimidex/femara/aromasin
or the legal OTC versions ie 6oxo or even better Rebound XT(ATD)
The use of an AI will allow for higher than normal consentrations of testosterone production and the use of ActivaTe will make it so you can actually use more of the the increased testosterone for muscle building purposes!!!