
Originally Posted by
IBdmfkr
I've always taken nolva when I had symptoms, letro didn't do much for me as far as gyno was concerned, but it did pull waterweight off quickly. Everyone is different, you may also try arimidex, it works wonders.
Letro will help prevent gyno and shed waterweight, but in my experience nolva has taken care of the problem when I felt/saw symtoms. I'd run the nolva until your gyno clears and then discontinue use of nolva and continue letro at .25-.5mg/day(taking too much can kill your sexdrive, You don't want that).
Here's a direct quote from Hooker's Letro(femara) profile. You'll have to decide which protocol works best for you, everyone is different, let this be your learning experience.
"How good is this compared with Aromasin and Arimidex, it’s too other main rivals? Well, In non-cellular systems, letrozole is 2-5 times more potent than anastrozole and exemestane in its inhibition of the aromatase enzyme and activity, and in cellular systems it is 10-20x more potent! It also lasts quite a long time in your body,but takes awhile to get going… Letrozole has a whopping 2-4 day (!) ½ life, and you need to take Letrozole for 60 days to get a steady blood plasma level (8).
Those are impressive numbers, but here’s one of the most interesting things about Letrozole:
It may reduce/eliminate/reverse existing gynocomastia!
In a study conducted on mice (*no, I know it’s not perfect), gyno-like-changes in the mammary gland were totally destroyed ! Here’s a direct quote from that study:
“Our results also indicate aromatase overexpression-induced changes in mammary glands can be abrogated [destroyed] with very low concentrations of the aromatase inhibitor, letrozole.”(7)
In addition, I’ve used Letro to get rid of my own gyno, as has a friend of mine, and we both used it at a dose of 2.5mgs/day, tapering down to .25mgs/day, and then finally off….the gyno never returned in both our cases.
I’d say that this stuff is pretty great, considering its availability and cost (when you consider the fact that .25mgs/day is more than enough protection from estrogen-related sides on most cycles), not to mention it’s overall utility for a variety of functions (destroying gyno, preventing estrogenic sides, and for PCT)."