Dutasteride Dosing...

[BigJames]

Can anyone comment on how much and how often one should take dutasteride to prevent hair loss during a 13 week Test Enan cycle (500mg/wk)? I read in another post to start it 1 week prior to the start of the cycle. If it matters - I am 30 years old, 235lbs, training for 10 years. This will be my first cycle - I have all my anti-e's and pct lined up.

Also, I am curious if anyone can comment on whether I even need durasteride with this cycle. I know that test causes DHT and that causes hairloss...but is it dependant on mg/week? or duration of cycle? or is it just a genetic predisposition thing? My father (age 58) has a full head of hair, my father's father (age 90) has all his hair. My mother's father is bald. My uncle on my mom's side is thining at age 55. My uncle on my father's side (age 65) has receding hair.

I do not particularly want to go bald if I can help it. But at the same time, I do not want to take stuff for no reason.


Thanks,

BigJ

[axemurderer187]

bumpity bump bump

[BigJames]

bump...anyone?

[axemurderer187]

someones gotta know something about this...

[BigJames]

someones gotta know something about this...

You would think so...but apparently not. I am not even sure if I will need this stuff, I just want to know how much I will need, if I need it...hahaha

[axemurderer187]

You would think so...but apparently not. I am not even sure if I will need this stuff, I just want to know how much I will need, if I need it...hahaha

DUDE, same here

I don't want to take a chance loosing my rug. If you find anything out let me know through PM and I'll do the same.. The questions in your post are EXACTLY what I need to know... Very good questions BTW.

[Anabolic CEO]

I take it bro.........i have been on it for about 1 year. Take it everyday while on and until gear leaves your system...5-6months. .5mg ED for 5-6 months, if you are prone.....once you are off of your cycle and it is out of your system you can take it EOD.

[BigJames]

DUDE, same here

I don't want to take a chance loosing my rug. If you find anything out let me know through PM and I'll do the same.. The questions in your post are EXACTLY what I need to know... Very good questions BTW.

Thanks bro, I will stay in touch and let you know what I find out...

BigJ

[BigJames]

I take it bro.........i have been on it for about 1 year. Take it everyday while on and until gear leaves your system...5-6months. .5mg ED for 5-6 months, if you are prone.....once you are off of your cycle and it is out of your system you can take it EOD.

Thanks CEO, I appreciate the response. Were you prone to hair loss before you used gear?

Thanks,

BigJ

[Anabolic CEO]

Make sure you take Anti-E while on it also. Dutasteride will convert DHT into Estrogen. i took 10-20mg Nolvadex every day while cycling and 40mg pct.

[Anabolic CEO]

Yeah i was before, during, and after...lol. It runs in the family and i am just trying to keep my follicles......<---they are weak. I love juice and i love my hair.......i just need to choose one though. If you are prone you will eventually lose it while taking juice down the road.

[BigJames]

Make sure you take Anti-E while on it also. Dutasteride will convert DHT into Estrogen. i took 10-20mg Nolvadex every day while cycling and 40mg pct.

I am not 100% on this, but isn't it more accurate to say that DHT is an anti-estrogen and by blocking the production of DHT you are also blocking an anti-e and therefore estrogen goes up? I am not an expert, I just read something on this a few minutes ago on another thread. Anyway, thanks for the input. I am leaning towards the idea that if I am prone to lose my hair, I will lose it so I might as well accept it.

Thanks,

BigJ

[Anabolic CEO]

I am not 100% on this, but isn't it more accurate to say that DHT is an anti-estrogen and by blocking the production of DHT you are also blocking an anti-e and therefore estrogen goes up? I am not an expert, I just read something on this a few minutes ago on another thread. Anyway, thanks for the input. I am leaning towards the idea that if I am prone to lose my hair, I will lose it so I might as well accept it.

Thanks,

BigJ

Yeah your right i just worded it wrong........Thanks bro.

[BigJames]

Yeah your right i just worded it wrong........Thanks bro.

No, thank you for your info. It seems like this is a subject that no one really wants to comment on or maybe not enough people are using this stuff...

Thanks again for posting.

BigJ

[sp9]

Used prosar 1998-2002, Avodart/Dutasteride 2002 to present.

.5mg daily is the standard dose.

Rise in estrogen coinsides with the rise in testosterone. Since much of the test is not converting to dht via the 5ar pathway more test remains. The FDA/Glaxo studies show a nice rise in test. It was not so much that I have ever needed a estrogen reducer/blocker when not on cycle.

I don't know why Lion took Finasteride/Proscar off his sales. I would recommend starting with proscar for these reasons:

1)Proscar has long term health studies (10years)/ Avodart just came out in 2002 so there are not even large scale 5 year studies.

2)Some people are very happy with proscar results for hair loss at 1mg per day. Proscar blocks 70% of 1 type of DHT. If you are happy with the results there is no reason to mess with your natural system further by blocking 92-94% and 2 types of dht with avodart/duta.

3) Avodart is more likely to cause shedding when used. If you use it while just on cycle and you get a massive shedding of hair from it you will scare yourself to death. Shedding is good in terms of a dht blocker because it means the reduction in DHT has caused a new growth cycle, so the existing hair falls out. Problem is, if you are using the drug just while on cycle you are going to not be happy if it increases hair loss while on cycle. Avodart after an initial shedding incident can take 3-6 months before you start to see those new thicker hairs make a cosmetic (in the mirror) difference.

Proscar is not known to cause shedding in so many people, because it is weaker. I would always recommend to those prone to hairloss to get on a dht blocker for good and not just while on cycle.

4) Just as using short estered steroids helps you control sides because the drug clears your system faster, same thing with these 2 alternatives. Proscar/Fina will be out of your system in a couple of days, Avodart/Duta has a half life around 14 days so it will take a long time to reverse sides by stopping.

If you are going to use just while on gear then proscar/finasteride is the clear winner.

Avodart/Duta is what you go to when you are not happy with Proscar/FIna results after 12 months of constant use.

All my opinion from my personal use and personal research on these drugs.

By the way, proscar/fina reaches maximum dht supression in about 2 weeks, avodart/duta is about the same.

As far as side effects go there is very little difference in the rate of sides when you compare the two in the available studies. To simplify this, you can think that when compared to placebo about 1 out of 100 people had an issue with proscar/fina and 2 out of 100 people had an issue with avodart/duta.

[powerliftmike]

I am not 100% on this, but isn't it more accurate to say that DHT is an anti-estrogen and by blocking the production of DHT you are also blocking an anti-e and therefore estrogen goes up? I am not an expert, I just read something on this a few minutes ago on another thread. Anyway, thanks for the input. I am leaning towards the idea that if I am prone to lose my hair, I will lose it so I might as well accept it.

Thanks,

BigJ

I am pretty sure direct conversion isnt possible. DHT could convert back into testosterone and then the test could covert to estradiol. That is kind of unlikely to happen tho.

[sp9]

I am pretty sure direct conversion isnt possible. DHT could convert back into testosterone and then the test could covert to estradiol. That is kind of unlikely to happen tho.

Agreed. It is clearly stated in studies that there is a rise in test because it is not converting via the 5ar pathway to DHT. That higher amount of test ends up resulting in more estrogen conversion and it the reason about 2 out of 100 people have a problem with nipple irritation and gyno.

[themetalmich]

Right on. I've just ordered some dutasteride. I've been on proscar for 7years, and it's time to kick it up a notch. Thanks for the good info.

[Kale]

Any comments on using Proscar with Deca ?

[DBflash21]

How do you determine if you are prone or not?

[themetalmich]

Any comments on using Proscar with Deca ?

yeah man. that's a no. no.
I kept hearing that you shouldn't take proscar while taking Deca, but I couldn't find any info as to why. So I continued taking my daily finasteride while taking deca. Well my hair started to fall out like crazy and then I found out why. I found it on a site called www.hairlossreaserch.org. I can no longer find that site.
It's in the section "steroids and hairloss" in that section it explains that Deca needs the 5 alpha reductase enzyme to convert itself into a milder androgen called DHN ( I think that's what it's called) anyway, if you block that conversion, you're in for some hairloss.

[Kale]

Interesting, so thats the only side ? I really dont give a shit about my hair to be honest.

[axemurderer187]

bump

[Dally]

bump.


what about dutasteride and something like EQ or Oral turnibol?

[sp9]

I have used test and eq cycles 3 times with dbol kick starts, no hair loss noticed while on avodart/duta. Last cycle was 15 weeks 600 mg eq weekly.

[Dally]

I have used test and eq cycles 3 times with dbol kick starts, no hair loss noticed while on avodart/duta. Last cycle was 15 weeks 600 mg eq weekly.

on a side note, how did you find the eq?

what were your goals?

[GoldieTheMack]

I am not 100% on this, but isn't it more accurate to say that DHT is an anti-estrogen and by blocking the production of DHT you are also blocking an anti-e and therefore estrogen goes up? I am not an expert, I just read something on this a few minutes ago on another thread. Anyway, thanks for the input. I am leaning towards the idea that if I am prone to lose my hair, I will lose it so I might as well accept it.

Thanks,

BigJ

Looks correct.
Then Nolva blocks new E levels.
Gold

[sp9]

From what I have seen from the drug studies and other secondary comments.

Taking a dht blocker, increases test, becasue it can not convert to dht. This is documented in the studies submitteed to the FDA.

If you're taking an estrogen blocker more test tries to go through the dht pathway. If dht suppression is a constant, like 70% of DHT blocked by proscar than the combination of higher test from the dht blocker and an estrogen conversion blocking drug, means more DHT will be produced, but still blocked at the same %.

I am not a biology, chemistry person, so I am sure there are people that could study the drugs and their interaction and come to alot better and more detailed conclusions then I am guessing at.

[GoldieTheMack]

Because Duta blocks Test conversion to DHT, doesn't mean your body produces more Test in an attempt to convert it. That receptor site (scalp) just lacks conversion. Just as when Nolva is used to block estrogen from developing gyno. The body doesn't attempt to increase output, rather those sites lack uptake. If anything, in both cases less is produced because now you have more free Test (first example) and Estrogen (second example) in the blood, since they were never converted and bound respectively.
Gold

[sp9]

Because Duta blocks Test conversion to DHT, doesn't mean your body produces more Test in an attempt to convert it. That receptor site (scalp) just lacks conversion. Just as when Nolva is used to block estrogen from developing gyno. The body doesn't attempt to increase output, rather those sites lack uptake. If anything, in both cases less is produced because now you have more free Test (first example) and Estrogen (second example) in the blood, since they were never converted and bound respectively.
Gold

I was not saying hte body produces more test. I was saying there was more in your system. I should have been more definitive in the statement.

I would urge everyone to not jut take the word of internet people you do not know. Talk to a local pharmacist about how the drugs interact and read all of the documentation and studies on each drug yourself. For example Dutasteride was shown to have an increasing effect in LH production of 19% even after 1 year in humans:

http://www.fda.gov/cder/foi/nda/2001...gen_pharmr.pdf