i took my 1st shot last thur afternoon.i have a pretty good size knot on my glute.its not really sore or anything.its pretty good size also.its right where the shot is to be.i was wondering what would be the best thing to do since its time for my next shot.i did everything right,cleaning the area and everything.i even went to another web site that only talks about shot and double checked to make sure i was doing it right.and this is my 2nd cycle.thanks for the info.