Ultrastructural analysis of ruptured tendon from anabolic steroid users.

[cj1capp]

I HAVE SUFFERED FROM THIS PERSONALY I AM LOOKING TO UNDERSTAND WHAT HAPPEND.HAS ANY READ OR HAVE A THEORY RELATED TO TENDON RUPTURE AND THE USE OF ANABOLIC STEROIDS. MORE TO THE POINT HAS ANY ONE RECOVERED AND RETURNED TO USE GEAR AND HEAVY WEIGHTS AFTER A TENDON RUPTURE. THANKS, AND HERE IS A LITLE THING I FOUND.

Tendon rupture has been linked with anabolic steroid abuse on the basis of a small number of published case reports. Although experimental data from animal models suggest steroids alter the biomechanical properties of tendon, ultrastructural evidence to support this theory is lacking. Indeed, microscopic analysis of human tendon from steroid users has not previously been reported. In this study, specimens of ruptured human tendon from four patients were biopsied during surgical repair. Two of the subjects were anabolic steroid users, and two subjects were used as nonsteroid-user controls. Ruptured tendon from both groups was examined using electron microscopy. No differences in collagen fibril ultrastructure were seen. We conclude that anabolic steroids did not induce ultrastructural collagen changes that might predispose to tendon rupture in humans.

[cj1capp]

Bump

[Property of Steroid.com]

On the issue of the body's structural integrity and steroids, here's my effort:

http://www.anthony-roberts.com/deca_...ol_joints.html

[cj1capp]

Thanks Anthony

[cj1capp]

AFTER READING YOUR ARTICLE WHAT ADVICE DO YOU HAVE TO COMBAT COLLEGEN DETERIOTION
" this reduction in Estrogen/Progesterone, caused by DHT, reduces your body's production of anti-inflammatory and painkilling cytokines. And this is what causes Winstrol, Masteron, etc to cause joint pain. And as noted at the beginning of this article, when one undergoes reductions in estrogen and progesterone, bone mineral density and collagen will suffer deleterious effects." BY AR

[magic32]

I HAVE SUFFERED FROM THIS PERSONALY I AM LOOKING TO UNDERSTAND WHAT HAPPEND.HAS ANY READ OR HAVE A THEORY RELATED TO TENDON RUPTURE AND THE USE OF ANABOLIC STEROIDS. MORE TO THE POINT...RECOVERED...HEAVY WEIGHTS AFTER A TENDON RUPTURE. THANKS, AND HERE IS A LITLE THING I FOUND.

Tendon rupture has been linked with anabolic steroid abuse on the basis of a small number of published case reports. Although experimental data from animal models suggest steroids alter the biomechanical properties of tendon, ultrastructural evidence to support this theory is lacking. Indeed, microscopic analysis of human tendon from steroid users has not previously been reported. In this study, specimens of ruptured human tendon from four patients were biopsied during surgical repair. Two of the subjects were anabolic steroid users, and two subjects were used as nonsteroid-user controls. Ruptured tendon from both groups was examined using electron microscopy. No differences in collagen fibril ultrastructure were seen. We conclude that anabolic steroids did not induce ultrastructural collagen changes that might predispose to tendon rupture in humans.

PLEASE ANSWER THIS: What did you tear, and can you recall the point (during your lift) at which injury occurred?

You seem to be in search of knowledge so bear with me as I provide some background to my response:

Tension 101:
As the load on the muscle increases, it finally reaches a point where the external force on the muscle is greater than the force that the muscle can generate. Thus even though the muscle may be fully activated (we describe this in terms of the number of recruited fibers), it is forced to lengthen due to the high external load (the reason people who don't do enough partials get elongated biceps). This is referred to as an eccentric contraction (please remember that contraction in this context does not necessarily imply shortening). There are two main features to note regarding eccentric contractions. First, the absolute tensions achieved are very high relative to the muscle's maximum tetanic tension generating capacity (you can set down a much heavier object than you can lift). Second, the absolute tension is relatively independent of lengthening velocity. This suggests that skeletal muscles are very resistant to lengthening. The basic mechanics of eccentric contractions are still a source of debate.

Now, I’d like to start by saying that I completely agree with study you cited. Everything I’ve learned and/or read has been consistent with this finding. For example:

“In humans, the combined increase in muscle strength with a potentially weakened tendon increases the rate of tendon rupture for patients who use anabolic steroids. However, many patients who have never used any form of anabolic agents also sustain tendon ruptures when training.”
- Robert G. Marx, Orthopedic Director of the Sports Medicine Institute for Young Athletes and the Director of the Center for Clinical Outcome Research at the Hospital for Special Surgery in New York City, and Assistant Professor of orthopedic surgery at Weill Medical College of Cornell University
http://www.ifbb.com/reports/tendons.html

It has been proven that the most common mechanism of bb’er injury is a forceful eccentric contraction. There are many types of muscle contraction. A concentric contraction is when a muscle contracts and it shortens in length, such as a dumbbell curl. The eccentric portion of the contraction occurs during the negative portion of the repetition. In cases where the eccentric contraction is rapid or uncontrolled, the tendon is at risk for rupture. In this situation, the muscle-tendon unit as a whole is lengthening rapidly, but the muscle itself remains in a contracted state. This places the tendon under a large stress and in certain cases, regardless of aas, it can tear. The lifter will feel sudden pain and will generally be unable to continue the workout. Swelling occurs rapidly and there is often significant bruising in the area. There are many tendons in the body that can rupture as described above. The mechanism of injury for each is different but the result is the same in terms of weakness. The most common tendons to rupture in the upper limb include the biceps, triceps, pectoralis major and the rotator cuff. In the lower extremity, the common tendons that rupture are the patellar tendon, the quadriceps tendon and the achilles.

You can read about bb’er rehab time for this type of injury, as well as expectations for strength and form (shape of the muscle) here: http://www.ifbb.com/reports/tendons.html

M.

[cj1capp]

i tore my rotator cuff almost 20 months ago , my surgeon said it was the most massive tear he has ever seen.
i attempted a lift, bench press of 465 i got the weight off the rack and then heard a massive pop! i had two spotters and with there help returned the weight to the rack. now im back in the gym just started back really about two weeks ago, but i am so weak and scared im searching for info and personal experience.

[magic32]

Really sorry to hear that man.
Glad you made it back though, and best to you.

M.

[cj1capp]

thanks magic