Dutastride is a fairly new compound which has proved very effective in treating genetic male pattern hair loss on the vertex (top of the head) and the mid-scalp area.
Dutastride was developed for treating symptomatic benign prostatic hyperplasia (BPH) in men. Dutastride is chemically similar to Finasteride, the active compound in Propecia, but has proven more effective in clinical trials. Like Propecia, Dutastride has proved to be effective in treating male pattern hair loss as well as BPH.
Researchers have discovered that men who suffer from either male pattern hair loss or benign prostatic hyperplasia (BPH), have increased levels of the hormone dehydrotestosterone (DHT).
DHT is produced from testosterone by an enzyme called 5-alpha-reductase. Biochemical analysis reveals higher levels of 5-alpha-reductase in the bloodstream of men with BPH, and in the scalps of men with hair loss; and less of this enzyme in men with no BPH or no hair loss.
Dutastride inhibits 5-alpha-reductase, blocking the formation of DHT. This interrupts a key trigger element in development of male pattern hair loss and in development of BPH.
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