Abcess?????

[dhriscerr]

Hey I shot left Tricep on monday and its still swollen a bit, doesn't hurt and no fever but its a tiny bit red and still swollen some, It was my first injection there and I know my first injection in my leg swelled a bit. Think I should be worried about it??? If i touch it is a bit warm but that might be because I wont leave it alone, how long should I let it go before looking at going to a doc??? Also I do have 4 Amoxicillin/Augmentin pills in my medicine cabnit and 40+ Dicloxacillan 500mg tabs, both are antibiotics. Should I take them??? Im starting to freak myself out here.

Dicloxacillan
Dicloxacillin (INN) is a narrow spectrum beta-lactam antibiotic. It is used to treat infections caused by susceptible Gram-positive bacteria. Notably, it is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. It is very similar to flucloxacillin and these two agents are considered interchangeable. Dicloxacillin is available under a variety of trade names including Diclocil (BMS).Like other β-lactam antibiotics, dicloxacillin acts by inhibiting the synthesis of bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall of Gram-positive bacteria.
Medicinal chemistry
Dicloxacillin is insensitive to beta-lactamase (also known as penicillinase) enzymes secreted by many penicillin-resistant bacteria. The presence of the isoxazolyl group on the side chain of the penicillin nucleus facilitates the β-lactamase resistance, since they are relatively intolerant of side-chain steric hindrance. Thus it is able to bind to penicillin binding proteins (PBPs) and inhibit peptidoglycan crosslinking, but is not bound by or inactivated by β-lactamases.
Clinical use
Dicloxacillin is more acid-stable than many other penicillins and can be given orally, in addition to parenteral routes. However, like methicillin, it is less potent than benzylpenicillin against non-β-lactamase-producing Gram-positive bacteria.
Dicloxacillin has similar pharmacokinetics, antibacterial activity and indications to flucloxacillin and the two agents are considered interchangeable. It is believed to have lower incidence of severe hepatic adverse effects than flucloxacillin, but a higher incidence of renal adverse effects. (Rossi, 2006)
Indications
Dicloxacillin is indicated for the treatment of infections caused by susceptible bacteria. Specific approved indications include: (Rossi, 2006)
Staphylococcal skin infections and cellulitis – including impetigo, otitis externa, folliculitis, boils, carbuncles, and mastitis
Pneumonia (adjunct) Osteomyelitis, septic arthritis
Septicaemia
Empirical treatment for endocarditis
Surgical prophylaxis
Precautions/contraindications
Dicloxacillin is contraindicated in those with a previous history of allergy to penicillins, cephalosporins or carbapenems. It should also not be used in the eye, or those with a history of cholestatic hepatitis associated with the use of dicloxacillin or dicloxacillin. (Rossi, 2006)
It should be used with caution in the elderly, patients with renal impairment, where a reduced dose is required; and those with hepatic impairment, due to the risk of cholestatic hepatitis. (Rossi, 2006)
Adverse effects
Common adverse drug reactions (ADRs) associated with the use of dicloxacillin include: diarrhoea, nausea, rash, urticaria, pain and inflammation at injection site, superinfection (including candidiasis), allergy, and transient increases in liver enzymes and bilirubin. (Rossi, 2006)
Rarely, cholestatic jaundice (also referred to as cholestatic hepatitis) has been associated with dicloxacillin therapy. The reaction may occur up to several weeks after treatment has stopped, and takes weeks to resolve. The estimated incidence is 1 in 15,000 exposures, and is more frequent in people >55 years, females, and those with treatment longer than 2 weeks. (Joint Formulary Committee, 2005; Rossi, 2006)
Resistance
Despite dicloxacillin being insensitive to beta-lactamses, some organisms have developed resistance to it and other narrow-spectrum β-lactam antibiotics including methicillin. Such organisms include methicillin-resistant Staphylococcus aureus (MRSA).

[dhriscerr]

?Anyone?

[cj1capp]

as you have the antibiotics on hand i would wait.
you dont have any solid sings or symptoms of an infection watch it closely and keep us updated.

[dhriscerr]

as you have the antibiotics on hand i would wait.
you dont have any solid sings or symptoms of an infection watch it closely and keep us updated.

You think dicloxicillan is a good antibiotic for an abcess, if infact that is what I have? how long should I wait and what should I wait for???

[dhriscerr]

Come on guys????

[ALPHAMALE77]

Dhriscerr, Thaught I Had The Same Problem A Few Weeks Ago...shot In Glute....swole Up Like A Bumble Bee Sting.....itchy And Red...no Pain Or Fever....lightly Hot.....imo Id Wip It With Alchol Pad Evey Hour Or So.....and Massage It Not Until It Get Sore But To Try To Get The Oil To Disipate...know...atleast That My 2 Cents Worth....give It 2 Weeks And TheN Not Better Go To Doc

[dhriscerr]

I think Im going to start taking dicloxacillan, just incase, im only going to take 2 pills aday instead of 4 and see where that gets me, I think it might be alittle less swollen this morning, but not much. Its not that bad and it doesn't seem to be a swollen lump exactly in the injection site, more like the whole tricep is swollen, that kinda leads me to think its just because its a virgin muscle, also no fever still and I can't even see the injection site anymore.

[cj1capp]

i you think you are fine but if you decide to take the antibiotic take a full dose and run it for the full length of time usually between 7 to 10 days other wise you just open your self to making any bacteria resistant to treatment.

[AnabolicBoy1981]

are you shooting prop?

[skipp]

IMO try and get ahold of some omnicef. But realistically it's prob not an abcess, but I understand being over cautious.

[dhriscerr]

It got really red tonight and warm when I was watching my wife's dad's football team do there strength day, And I was kind of freaking out, but it kinda felt like when your fever breaks if you have one, all of a sudden it wasnt warm and the swelling went down, now its back to normal size i think, or if its not its close, I took 3 antibiotic pills should I finish now that I started or becuase its only been one day should I stop???

[dhriscerr]

Im shooting Enathate, tonight was my 12th shot, right quad. only had 2 swellings, very first shot in right quad and 1st shot in tricep

[skipp]

Continue the antibiotics for a few more days at the same dose, because if there was anything, the last thing you want is it coming back to bite you in the arse.

[TheSentinal]

It got really red tonight and warm when I was watching my wife's dad's football team do there strength day, And I was kind of freaking out, but it kinda felt like when your fever breaks if you have one, all of a sudden it wasnt warm and the swelling went down, now its back to normal size i think, or if its not its close, I took 3 antibiotic pills should I finish now that I started or becuase its only been one day should I stop???

I would stop the antibiotics if your arm is ok. Antibiotics interfere with protien synthesis and will not help you build muscle.

[K.Biz]

I would stop the antibiotics if your arm is ok. Antibiotics interfere with protien synthesis and will not help you build muscle.

it sounds like the anti-biotics is what is helping his arm. no need to build muscle if you have an abcess. i would continue to run the anti-biotics for another 7 days. then come off.