Tolerance to Letro?

[reddragon4954]

Can you build up a tolerance w/ letro if you used it for a prolonged period?

If you were to develop a resistance could you simply up the dose to counteract this?

[kfrost06]

I haven't heard of people building a tolerance to it and I would hope that you would not be on it long enough to find out if there is a tolerance to it. Letro is very potent, the strongest AI out there. Be careful with it because the sides are bad. However, you can experience an estrogen rebound when coming off it and thats why it's very important to titrate down rather then to stop abruptly. GL

[Cocklyaev]

I personally did build a sort of tolerance to it, so i know what you may be going through. I would get off it, take nolva for a little bit, and try another AI. Letro worked great for me in short doses, but when i stayed on 2.5 every day for a while to reverse gyno i just turned into a zombie.