DNP Problems!

[tRaNs]

I have 10 days taken dnp ... 200,400 and now 600mg per day.

last night, i couldn't sleep, like others days, and i felt itching in all my body, well,
where I felt itching I scratched it, but in a while, where I scratched it Appear a kind of rash... another thing, I felt my finger like fats, my fingers were swollen, and my palm was yellow-

I took some cetirizina, like benadryl but newer, and in the morning I was fine with the rash. But my palm is right now very very yellow, is it for the dnp? because i took T3 the last month.

what Should I do?

[magic32]

I have 10 days taken dnp ... 200,400 and now 600mg per day.

last night, i couldn't sleep, like others days, and i felt itching in all my body, well,
where I felt itching I scratched it, but in a while, where I scratched it Appear a kind of rash... another thing, I felt my finger like fats, my fingers were swollen, and my palm was yellow-
I took some cetirizina, like benadryl but newer, and in the morning I was fine with the rash. But my palm is right now very very yellow, is it for the dnp?
YES.

because i took T3 the last month.

what Should I do?

DISCONTINUE DNP NOW!

I'm sorry to hear that.
This means you've successfully achieved the level of moderate toxic poisoning. Such a level by intentional consumption is rare and depicts extended usage (as DNP toxicity is cumulative), or high initial doses (such as starting at and maintaining 600 mgs).

There are three distinct levels of poisoning, e. g. mild, moderate, and severe which can be fatal, but also hybrid or in between levels. Your symptoms are clearly moderate including jaundice (yellow coloration of the skin on the hands and feet) and hypersensitivity (of the nerves). The latter resembles itching without due cause that is often brought on by the brushing of clothing or bedding against the skin. This condition is readily exacerbated by scratching, as the nerves go from irritated to inflamed and skin reddens, often resulting in welts from the fingernails. Rubbing doesn't help either.

Should poisoning continue the next phase (moderate to severe) includes vertigo, peripheral neuritis or neuropathy during which these same nerves stop firing and fail to function properly, resulting in pain, loss of sensation, and eventually the inability to control muscles, and variety of other such nasties.

Be sure to read my signature threads when you get a chance and my highlights below.

PROMINENT MODERATE POISONING SYMPTOMS:

Symptoms of exposure to this compound may include profuse sweating,
fever, shortness of breath and yellow coloration of the skin of the hands
and feet [036]. Other symptoms may include a marked increase in metabolism,
nausea, vomiting, collapse, death, cataracts, weight loss, granulocytopenia,
polyneuropathy and exfoliative dermatitis [033]. Skin irritation may also
occur [043]. Exposure to this compound may also cause disruption of oxidative
phosphorylation, increased oxygen consumption, fatigue, intense thirst, sweating,
oppression of the chest, anorexia, weakness, dizziness, vertigo, headache,
sensitivity of the liver to pressure, jaundice and hypersensitivity, neutropenia,
skin rashes and peripheral neuritis [346]. Other symptoms may include
degenerative changes in the heart, liver and kidneys, cyanosis, lividity,
tremors and coma [301]. Contact may also cause irritation of the eyes and
mucous membranes [269]. Secondary glaucoma may also result [099]. Exposure
to this compound may cause restlessness, flushed skin, tachycardia and fatal
hyperthermia [406]. Allergic reactions may also occur [051]. Other symptoms
may include hyperpyrexia, acidosis, dehydration, muscle rigor, pulmonary edema,
a**ominal pain and diarrhea [151]. Anxiety and delirium may also result [430].
Other symptoms may include liver damage, dilation of the pupils, smarting of
the skin and skin burns [371].
http://www-unix.oit.umass.edu/~jmfie...itrophenol.htm

Sadly, once you've breached moderate poisoning the chemical has passed blood saturation and become thoroughly embedded within your tissues as seen on pgs. 3, 9, 12, 15 & 20 of the Toxicology Evaluation (https://www.bgchemie.de/files/95/ToxBew239-E.pdf), which takes far longer to evacuate the body. Thus, you can expect to feel this level of symptoms for the next week or so, then a gradual lessening for another couple of weeks.

This really isn't that bad, I've seen much worse cases. So you can wait it out or focus on assisting the body in its natural removal of built-up toxins. Should you elect the latter, be sure to start distilled water (a gallon a day, or as much as tolerable) which possesses the reverse osmosis effect of attaching itself to free toxins as it washes through, as well as the benefit of not contributing to poison build up. Regular tap water contains a host of germ fighting poisonous chemicals (chlorine, fluoride, etc.) in minuscule amounts that are best avoided at this time. It would also greatly benefit you to begin an internal cleansing program (should be done every 6 months anyway) which will facilitate blood, organ, and tissue detoxification via a specific combination of herbs and extracts. It sounds complex but really only amounts to one tab am & one pm, increasing both by one daily until three bowl movements occur ED. Here's a good one: http://www.gnc.com/product/index.jsp...entPage=search

Note: Don't elect to save the $6 by purchasing the very similar GNC brand version. I once tried it and, though the elements are similar the composition is different, making it less effective. I run these twice annually.

Don't bother with increasing vits & mins because they'll just add to toxicity. And don't start loading up on antioxidants in caps or most pure juices (grapefruit, cranberry, cherry, etc.) since they primarily fight infectious bacterium and viruses. Toxicity is a different creature altogether.

You'll be fine, and even better for having the experience!

[IntenseAthlete]

^^^^^^^^^magic is the man

[tRaNs]

DISCONTINUE DNP NOW!

I'm sorry to hear that.
This means you've successfully achieved the level of moderate toxic poisoning. Such a level by intentional consumption is rare and depicts extended usage (as DNP toxicity is cumulative), or high initial doses (such as starting at and maintaining 600 mgs).

There are three distinct levels of poisoning, e. g. mild, moderate, and severe which can be fatal, but also hybrid or in between levels. Your symptoms are clearly moderate including jaundice (yellow coloration of the skin on the hands and feet) and hypersensitivity (of the nerves). The latter resembles itching without due cause that is often brought on by the brushing of clothing or bedding against the skin. This condition is readily exacerbated by scratching, as the nerves go from irritated to inflamed and skin reddens, often resulting in welts from the fingernails. Rubbing doesn't help either.

Should poisoning continue the next phase (moderate to severe) includes vertigo, peripheral neuritis or neuropathy during which these same nerves stop firing and fail to function properly, resulting in pain, loss of sensation, and eventually the inability to control muscles, and variety of other such nasties.

Be sure to read my signature threads when you get a chance and my highlights below.

PROMINENT MODERATE POISONING SYMPTOMS:


Sadly, once you've breached moderate poisoning the chemical has passed blood saturation and become thoroughly embedded within your tissues as seen on pgs. 3, 9, 12, 15 & 20 of the Toxicology Evaluation (https://www.bgchemie.de/files/95/ToxBew239-E.pdf), which takes far longer to evacuate the body. Thus, you can expect to feel this level of symptoms for the next week or so, then a gradual lessening for another couple of weeks.

This really isn't that bad, I've seen much worse cases. So you can wait it out or focus on assisting the body in its natural removal of built-up toxins. Should you elect the latter, be sure to start distilled water (a gallon a day, or as much as tolerable) which possesses the reverse osmosis effect of attaching itself to free toxins as it washes through, as well as the benefit of not contributing to poison build up. Regular tap water contains a host of germ fighting poisonous chemicals (chlorine, fluoride, etc.) in minuscule amounts that are best avoided at this time. It would also greatly benefit you to begin an internal cleansing program (should be done every 6 months anyway) which will facilitate blood, organ, and tissue detoxification via a specific combination of herbs and extracts. It sounds complex but really only amounts to one tab am & one pm, increasing both by one daily until three bowl movements occur ED. Here's a good one: http://www.gnc.com/product/index.jsp...entPage=search

Note: Don't elect to save the $6 by purchasing the very similar GNC brand version. I once tried it and, though the elements are similar the composition is different, making it less effective. I run these twice annually.

Don't bother with increasing vits & mins because they'll just add to toxicity. And don't start loading up on antioxidants in caps or most pure juices (grapefruit, cranberry, cherry, etc.) since they primarily fight infectious bacterium and viruses. Toxicity is a different creature altogether.

You'll be fine, and even better for having the experience!

thanks a lot...

I really apreciate that you're wasting your time in my stuff... it has been very helpfull to me... yesterday I was really scared, but, people like you make things easiest and make feel us more comfortable with information.

[MaGiCJNG]

Wow dude well said!!! I have been reading a little about DNP for a friend and i have come to the conclusion its just not worth it.

[JasonR]

thanks a lot...

I really apreciate that you're wasting your time in my stuff... it has been very helpfull to me... yesterday I was really scared, but, people like you make things easiest and make feel us more comfortable with information.

we are used to it magic IS the man.

[Jay-Ace]

DISCONTINUE DNP NOW!

I'm sorry to hear that.
This means you've successfully achieved the level of moderate toxic poisoning. Such a level by intentional consumption is rare and depicts extended usage (as DNP toxicity is cumulative), or high initial doses (such as starting at and maintaining 600 mgs).

There are three distinct levels of poisoning, e. g. mild, moderate, and severe which can be fatal, but also hybrid or in between levels. Your symptoms are clearly moderate including jaundice (yellow coloration of the skin on the hands and feet) and hypersensitivity (of the nerves). The latter resembles itching without due cause that is often brought on by the brushing of clothing or bedding against the skin. This condition is readily exacerbated by scratching, as the nerves go from irritated to inflamed and skin reddens, often resulting in welts from the fingernails. Rubbing doesn't help either.

Should poisoning continue the next phase (moderate to severe) includes vertigo, peripheral neuritis or neuropathy during which these same nerves stop firing and fail to function properly, resulting in pain, loss of sensation, and eventually the inability to control muscles, and variety of other such nasties.

Be sure to read my signature threads when you get a chance and my highlights below.

PROMINENT MODERATE POISONING SYMPTOMS:


Sadly, once you've breached moderate poisoning the chemical has passed blood saturation and become thoroughly embedded within your tissues as seen on pgs. 3, 9, 12, 15 & 20 of the Toxicology Evaluation (https://www.bgchemie.de/files/95/ToxBew239-E.pdf), which takes far longer to evacuate the body. Thus, you can expect to feel this level of symptoms for the next week or so, then a gradual lessening for another couple of weeks.

This really isn't that bad, I've seen much worse cases. So you can wait it out or focus on assisting the body in its natural removal of built-up toxins. Should you elect the latter, be sure to start distilled water (a gallon a day, or as much as tolerable) which possesses the reverse osmosis effect of attaching itself to free toxins as it washes through, as well as the benefit of not contributing to poison build up. Regular tap water contains a host of germ fighting poisonous chemicals (chlorine, fluoride, etc.) in minuscule amounts that are best avoided at this time. It would also greatly benefit you to begin an internal cleansing program (should be done every 6 months anyway) which will facilitate blood, organ, and tissue detoxification via a specific combination of herbs and extracts. It sounds complex but really only amounts to one tab am & one pm, increasing both by one daily until three bowl movements occur ED. Here's a good one: http://www.gnc.com/product/index.jsp...entPage=search

Note: Don't elect to save the $6 by purchasing the very similar GNC brand version. I once tried it and, though the elements are similar the composition is different, making it less effective. I run these twice annually.

Don't bother with increasing vits & mins because they'll just add to toxicity. And don't start loading up on antioxidants in caps or most pure juices (grapefruit, cranberry, cherry, etc.) since they primarily fight infectious bacterium and viruses. Toxicity is a different creature altogether.

You'll be fine, and even better for having the experience!

Very speculative however still sound advice, with the exception that you most likely do not have jaundice so do not look into this any further.

You more likely have discoloured skin from DNP's ability to dye just about anything it encounters!!


I would keep up teh anti-oxidant intake as the primary function for these compounds is to "mop up" nasty ions in the ... Like Magic said I wouldn't "load up" on them but certainly keep up your intake that you've been on up to now.

[RBIZZY]

damn magic..... where do you get all this? you are the man!

[magic32]

Very speculative however still sound advice, with the exception that you most likely do not have jaundice so do not look into this any further.

You more likely have discoloured skin from DNP 's ability to dye just about anything it encounters!!

I would keep up teh anti-oxidant intake as the primary function for these compounds is to "mop up" nasty ions in the ... Like Magic said I wouldn't "load up" on them but certainly keep up your intake that you've been on up to now.

There's NOTHING speculative about it. I have researched DNP poisoning in some detail, I'm not sitting around making this stuff up, nor was he merely confused as you assert when he said his entire body and palms were itching with yellowing of the latter. He meant yellowing from the inside out, not stained from touching DNP as per your conclusion.

There's no need to feel competitive about this, just help out where you can as we all do. But if you can't help, other than criticizing ACTUAL assistance, just sit back and take a...

Best to you.

[Jay-Ace]

There's NOTHING speculative about it. I have researched DNP poisoning in some detail, I'm not sitting around making this stuff up, nor was he merely confused as you assert when he said his entire body and palms were itching with yellowing of the latter. He meant yellowing from the inside out, not stained from touching DNP as per your conclusion.

There's no need to feel competitive about this, just help out where you can as we all do. But if you can't help, other than criticizing ACTUAL assistance, just sit back and take a...

Best to you.

Nothing competitive at all magic... Just correcting the comment!!

DNP poisoning is not known to increase Bilirubin (a blood by-product) levels which is the cause of Jaundice... What I was meaning is that he most likely is not suffering from Jaundice but rather the yellowing is from the DNP dying his tissues, and yes from the inside out.

I'm with you on the quest for knowledge magic so don't take it as counter-productive, I myself have researched this quirky compound for many many hours and would just like to make sure people have the whole picture.

Peace Out, Jay

[equipped]

Trans,

Did you follow the vitamin/supplement guidance posted on this board?? There are alot of vitamins you can/could of taken to help you not get sick! DNP is not a chemical to mess around with, as you have seen. Also was this your first time using it??

[magic32]

Nothing competitive at all magic... Just correcting the comment!!

DNP poisoning is not known to increase Bilirubin (a blood by-product) levels which is the cause of Jaundice... What I was meaning is that he most likely is not suffering from Jaundice but rather the yellowing is from the DNP dying his tissues, and yes from the inside out.
INTERESTING!
I'VE NEVER HEARD OF INTERNAL DYING, PLEASE EXPAND AND SUPPORT. ALL ACCOUNTS I'VE SEEN ARE STAINING FROM TACTILE EXPOSURE.

Peace Out, Jay

Glad to hear there’s no ill will.
I find you to be quite knowledgeable and your posts often accurate. Consequently, I’m not arguing the veracity of your statements in this instance, but rather their application. For example, you correctly cited jaundice as the result of increased bilirubin levels for which there are numerous possible blood and liver disorder causes.

Similarly, I wasn’t refuting DNP’s ability to impose tactile staining/discoloration, but rather citing how grossly misaligned such a cause would be with the severity of Trans' poisoning symptoms. And that's where our accord diverges on this matter, because even though many studies indicate that DNP has an inhibitory effect on bilirubin, they thus suggest due to the definitively conclusive jaundice/internal yellowing effect that there are secondary reactions at play during greater levels of exposure, most likely the onset of toxic hepatitis a jaundice initiator (http://www.mayoclinic.com/health/tox...811/DSECTION=2; http://www.mayoclinic.com/health/tox...811/DSECTION=3) as evidenced by many established authoritative sources on chemical poisoning. This brings us full circle to your quest for knowledge, and here are a few citations from the aforementioned authorities that should be of interest to you, and anyone else open to paradigm shifts congruent with new information:

Note: Toxic effects often appear at blood concentrations greater than 30 mg/l while concentrations greater than 60 mg/l are associated with severe toxicity.

National Toxicology Program (NTP)
Department of Health and Human Services (DHHS)
http://ntp.niehs.nih.gov/index.cfm?objectid=E88480B4- B D B 5 -82F8-F0E02E97762F7110
(remove above link spaces)

Human Toxicity Excerpts

• TOXIC SYMPTOMS /OF 2-AMINO-4,6-DINITROPHENOL ARE/ SIMILAR TO 2,4-DINITROPHENOL ...PRODUCES MARKED INCR IN METABOLISM & TEMPERATURE, PROFUSE SWEATING, COLLAPSE, DEATH. MAY CAUSE DERMATITIS, CATARACTS, WT LOSS, GRANULOCYTOPENIA, POLYNEUROPATHY, EXFOLIATIVE DERMATITIS. /2,4-DINITROPHENOL/ [The Merck Index. 9th ed. Rahway, New Jersey: Merck & Co., Inc., 1976., p. 964]**PEER REVIEWED**
• SYMPTOMATOLOGY: 1. MARKED FATIGUE, TREMENDOUS THIRST, PROFUSE SWEATING, FLUSHING OF FACE. 2. NAUSEA, VOMITING, A**OMINAL PAIN, & OCCASIONALLY DIARRHEA. 3. RESTLESSNESS, ANXIETY, EXCITEMENT, OCCASIONALLY LEADING TO CONVULSIONS. /DINITROPHENOL/ [Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. III-135]**PEER REVIEWED**
• SYMPTOMATOLOGY: 4. RISE IN BODY TEMP...ROUGHLY PROPORTIONAL TO TOXIC DOSE, MAY CULMINATE IN SEVERE HYPERPYREXIA... 5. TACHYCARDIA, HYPERPNEA, DYSPNEA, CYANOSIS, &...MUSCLE CRAMPS. 6. LOSS OF CONSCIOUSNESS, CESSATION OF BREATHING, & DEATH. /DINITROPHENOL/ [Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. III-135]**PEER REVIEWED**
• SYMPTOMATOLOGY: 7. LATE COMPLICATIONS: A. DECR URINE OUTPUT WITH ALBUMINURIA, CASTS, PIGMENTS, SOMETIMES BLOOD CELLS, DUE TO TOXIC NEPHRITIS. B. JAUNDICE & TENDERNESS IN LIVER REGION DUE TO TOXIC HEPATITIS. /DINITROPHENOL/ [Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. III-135]**PEER REVIEWED**
• SYMPTOMATOLOGY: 8. OCCASIONAL HYPERSENSITIVITY REACTIONS AFTER REPEATED EXPOSURES (OR IN CHRONIC POISONING) INCLUDE AGRANULOCYTIC ANGINA, SKIN RASHES, PERIPHERAL NEURITIS, & LATE CATARACT FORMATION. /DINITROPHENOL/ [Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. III-135]**PEER REVIEWED**

National Pesticide Information Center (NPIC)
http://npic.orst.edu/RMPP/rmpp_ch11.pdf

Signs and Symptoms of Poisoning (DNP pgs. 105-106)

Most patients present within a few hours of exposure with generalized non-specific signs and symptoms including profuse sweating, thirst, fever, headache, confusion, malaise, and restlessness. The skin may appear warm and flushed as hyperthermia develops, along with tachycardia, and tachypena, all of which indicate a serious degree of poisoning. Apprehension, anxiety, manic behavior, seizures, and coma reflect cerebral injury; seizures and coma signify an immediately life-threatening intoxication. Labored breathing and cyanosis are consequences of the stimulated metabolism and tissue anoxia. Renal failure may occur early in cases of severe exposure. Liver damage is first manifested by jaundice, and cell death can occur within 48 hours and is dose-dependent. Death may occur within 24 to 48 hours after exposure in cases of severe poisoning. In cases of survival of severe poisoning, complete resolution of symptoms may be slow due to the toxicant’s long half-life.

The International Programme on Chemical Safety (IPCE)
An affiliate of the World Health Organization (WHO)
http://www.who.int/ipcs/publications...en/index3.html

Signs and symptoms (Chemicals are listed alphabetically)
*If swallowed
Within a few hours:
-yellow skin, especially on the palms of the hands [as described by Trans, but not fingers which would logically also be implicated in external staining], and yellow hair, but the whites of the eyes do not turn yellow (dinitro-o- cresol and dinoseb only),
sweating and thirst,
-nausea and vomiting,
-high fever,
-dehydration,
-tiredness,

[Jay-Ace]

Magic...

Indeed the 3rd citation does state yellow staining whilst shying away from mentioning Jaundice... As in this and the cited quote the concentration would not be great enough to cause toxic hepatitis and thus Jaundice. It might be worth noting that true Jaundice manifests from the head down in most cases and is usually immediately noticeable on sclera (eye whites) before elsewhere.

From memory I cannot recall a case of of hepatic failure at a dosage which would be knowingly ingested however I appreciate your effort in posting the relevant information... It is most informative and I shall take the time to digest it when I have sufficient time, I am actually moving onto the liver in my studies in just 2 months so no doubt it will come up too

As for the yellow staining at extremities... From memory I recall this was attributed to accumulation in areas that have relatively low capillary pressure such as hands and feet. Unfortunately I'm about 3 system restores later from all my research so don't have any support for this so shall leave it as hear say

Cheers for the drink magic and merry xmas,

Jay

[Jeff1]

hope your feeling better