Oral's/Anavar better absorbed on empty stomach,or with fats?

[dedic8ed1]

Just want some opinions on the best absorbtion ability when taking orals.I've read that taking orals with fats has a better rate of absorbtion but how do you guys feel on this subject.

[longhorn814]

take them with grapefruit juice..it supposedly helps with absorption

[dedic8ed1]

take them with grapefruit juice..it supposedly helps with absorption

Will do thanks buddy.

[respek]

where did you get the grapefruit juice helping absorption info?

[bigswole32]

I heard the same thing. has something to do with the acid.

[bigswole32]

where did you get the grapefruit juice helping absorption info?

http://www.australianprescriber.com/magazine/29/2/40/2/

[dedic8ed1]

Any more info in this would be good,keep'em coming guys.

[ecto9]

take them with grapefruit juice..it supposedly helps with absorption

What he said ^^. Learned that from CaptainDominate. Used in in my var cycle and was able to lower my dose and got great results They make a product with the active ingredient in the juice, think it's called DHB or something.

I've found medicatins taken on an empty stomach are absorbed quicker and are more potent. (Lots of exp with varying meds!). As long as it doesn't cause you any stomach upset you'll be fine.

Check it:

http://todaystotalhealth.net/misc_nu...es_DHB_300.htm

[bigswole32]

Co-ingestion of grapefruit juice and certain drugs (Table 3) significantly increases their bioavailability because the constituents of the juice inhibit pre-systemic drug metabolism or transport. This increase in bioavailability can lead to excessive beneficial or adverse effects.2 The effects of grapefruit juice are complex and have been widely studied.3,4

A single glass of grapefruit juice is enough to increase the bioavailability of some drugs. If the juice is drunk over several days the effects are long-lasting3,4, so simply separating the dose of medicine and the ingestion of grapefruit juice does not prevent the interaction. For this reason grapefruit juice ingestion should be avoided completely with certain drugs, for example cyclosporin.

Could grapefruit juice be routinely used to enhance the bioavailability of some medicines? The answer would appear to be no because the effect of grapefruit juice on drug absorption is highly variable. It depends on the constituents of the juice, how it is prepared and varies with brands and batches.

Grapefruit juice is not 'pharmaceutical grade' or consistently of the same 'quality', so co-administration with a drug would lead to a variable response.

[respek]

So what is the final verdict people? Orals on an empty stomach, with food, or with grapefruit juice?

[james21]

empty with grapefruit juice or blood orange .... its something with the pigment, it isnt exactly the absorbtion it increases but the actual serum levels

[james21]

and extends the half-life

[TheJuicer]

I used my Var with my breakfast and it worked big time!! Def. my favorite oral!

[dedic8ed1]

Co-ingestion of grapefruit juice and certain drugs (Table 3) significantly increases their bioavailability because the constituents of the juice inhibit pre-systemic drug metabolism or transport. This increase in bioavailability can lead to excessive beneficial or adverse effects.2 The effects of grapefruit juice are complex and have been widely studied.3,4

A single glass of grapefruit juice is enough to increase the bioavailability of some drugs. If the juice is drunk over several days the effects are long-lasting3,4, so simply separating the dose of medicine and the ingestion of grapefruit juice does not prevent the interaction. For this reason grapefruit juice ingestion should be avoided completely with certain drugs, for example cyclosporin.

Could grapefruit juice be routinely used to enhance the bioavailability of some medicines? The answer would appear to be no because the effect of grapefruit juice on drug absorption is highly variable. It depends on the constituents of the juice, how it is prepared and varies with brands and batches.

Grapefruit juice is not 'pharmaceutical grade' or consistently of the same 'quality', so co-administration with a drug would lead to a variable response.

This no doubt has caused me a little anaylis paralisis.So what's a safe bet?