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  1. #1
    Amorphic's Avatar
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    Androgen Insensitivity Syndrome

    Androgen Insensitivity Syndrome

    I was reading about this today and a few questions popped into my mind.

    for starters, i'll explain what AIS is if you dont know:

    Androgen insensitivity syndrome (AIS, or "Androgen resistance syndrome") is a set of disorders of sexual differentiation that results from mutations of the gene encoding the androgen receptor.[1] It has also been called androgen resistance in the medical literature. The nature of the resulting problem varies according to the structure and sensitivity of the abnormal receptor. Most of the forms of AIS involve variable degrees of undervirilization and/or infertility in XY persons of either gender.

    there is partial and full AIS, partial males have normal development but may be infertile.

    my question is this:

    if you had AIS to some degree, either full or partial, and you ran a cycle of anablolic steroids , would you not respond at all and experience no gains, libido etc?

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  3. #3
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    I believe that some people (me included) are less sensible to AAS substances and have to shot a shit load of gears in order to get the desired results and effects from them.
    Though I don't know if this is talking about AIS.

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    AIS is serious and Iam sure you dont have this condition even in mild form.

    AIS patients is female with XY genotype and blind vagina mild form is characterised by some form of genital malformation and hypogonadism state (low libido, thin body hair, no facial hair, no deepr voice etc.) and with high test blood level.

    So you can put to this person 10,000mg test/week and see no efect from androgens but you will se some form of estrogen effect (test converted to estro).

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    Quote Originally Posted by XNathan View Post
    AIS is serious and Iam sure you dont have this condition even in mild form.

    AIS patients is female with XY genotype and blind vagina mild form is characterised by some form of genital malformation and hypogonadism state (low libido, thin body hair, no facial hair, no deepr voice etc.) and with high test blood level.

    So you can put to this person 10,000mg test/week and see no efect from androgens but you will se some form of estrogen effect (test converted to estro).
    yeah i wasnt insinuating i have it, i was just reading about it and thought it would be an interesting question

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    XNathan's Avatar
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    Quote Originally Posted by ChuckLee View Post
    I believe that some people (me included) are less sensible to AAS substances and have to shot a shit load of gears in order to get the desired results and effects from them.
    Though I don't know if this is talking about AIS.
    This is pure fact that you are far behind your genetic limit. You cant grow with AAS to infinity. You are still dependent on you genes. Sad but true.

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    Quote Originally Posted by Amorphic View Post
    yeah i wasnt insinuating i have it, i was just reading about it and thought it would be an interesting question
    Maybe it was towards me

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    We can speculate about AR polymorphism and diferent sensitivity. But this is far behind our knowledges and posibilities.

    Everthink what we say will be pure theory and guess.

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    Quote Originally Posted by ChuckLee View Post
    Maybe it was towards me
    Nothink bad, but you will be men without any sign of AIS. Just you are to far behind genetic limits and you need shit load of gear for more progress.

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    Quote Originally Posted by XNathan View Post
    Nothink bad, but you will be men without any sign of AIS. Just you are to far behind genetic limits and you need shit load of gear for more progress.
    True, mate

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  14. #14
    Amorphic's Avatar
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    anyone?

  15. #15
    lex57's Avatar
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    Quote Originally Posted by DSM4Life View Post
    whats a bmup?

  16. #16
    Sas29 is offline New Member
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    Quote Originally Posted by XNathan View Post
    AIS is serious and Iam sure you dont have this condition even in mild form.
    .
    I have this condition in mild form. Done many cycles and never gained a pound of muscle. Strength and libido went through the roof though.

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