Test Flu...

[fanatic]

How long does it usually take for the test flu symptoms to subside (short esthered)? I've never had to deal with this before... just curious about any experiences. Thanks, fellas.

[Dinosaur]

usually it depends ob u body. but generally speaking for a healthy man it any where from 3 to 5 days. don't froget to take ur multivitamin it'll help.

[calgarian]

bump

[nhl1]

I usually lose it in a day or so, and I tend to feel a little achey after just about every injection. Hence why I stay away from short esters.

Dayquil/Nyquil works well for me.

[Mulciber]

just wondering.. what to you think the reason behind the symptoms are.. just your body's reaction to the sudden increase in exogenous hormone levels..combination of sudden increased hormone levels and a foreign substance being injected into the muscle .
or maybe a connection between high BA content and immune response.
or even more likely due to the release of interleukin-1 from the leukocytes that are mobilized in response to the steroid injections..
maybe even just coincidence

[Reed]

I thought it was just your body reacting to a foreign substance injected into the muscle and had nothing to do with the hormones

[inky-e]

Just take a shitload of vitamin C...give it a week.

[Mulciber]

etiocholanolone represents about 20% of the metabolites of testosterone in people. could be that some people that experience this reaction to testosteone have particularly high levels of 17 beta hydroxysteroid dehydrogenase, the enzyme that converts testosterone into etiocholanolone.. maybe thats why some people suffer this and some dont.

Etiocholanolone is believed to produce fever and flu-like aches and pains because it induces the systemic release of Interleukin-1, a powerful proinflammatory cytokine:

Pyrogenicity of etiocholanolone and interleukin-1 in New and Old World Monkeys.

Steinetz BG, Randolph C, Werner R, Mahoney CJ.

New York University Medical Center, Laboratory for Experimental Medicine and Surgery in Primates, Tuxedo 10987, USA. [email protected]

Etiocholanolone (5beta-androstan-3alpha-ol-17-one; designated E) is one of the major products of metabolism of testosterone and androstenedione (androst-4-ene-3,17-dione) in many mammalian species, including humans. E and several other 5beta-reduced steroids have been found to induce fever in humans. The pyrogenic effect of these steroids has been shown to be due to the release of interleukin-1 (IL-1) from the leukocytes that are mobilized in response to the steroid injections. Old World Monkeys such as Rhesus monkeys (Macaca mu/atta), metabolize androgens similarly to humans, and E is a normal metabolite. However, New World Monkeys such as Squirrel monkeys (Saimiri sciureus), lack hepatic 5alpha- and 5beta-steroid reductases and excrete androgens primarily in an unaltered state; E is not produced. Therefore, we postulate that Squirrel monkeys likewise may have lost the ability to respond to 17-ketosteroids such as E. To test this hypothesis, adult male Rhesus and Squirrel monkeys were treated with E, and their rectal temperatures were recorded over a 24-hr period. Rhesus monkeys exhibited a rise of up to 3 degrees F following E injection. Squirrel monkeys, on the other hand, did not exhibit any increase in rectal temperature over the 24-hr period, even when doses up to 250 times the effective human dose were used. However, both species responded to injected IL-1alpha with a robust increase in rectal temperature. The data show that E is pyrogenic in Rhesus, but not Squirrel monkeys. The findings support the notion that injected E may induce release of IL-1 in Rhesus monkeys, but not in Squirrel monkeys.

[mrtosa]

Does anaprox will help with pain and flu?